Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for CANTHARIDINZ-score WebGraph NB WebGraph
Targetspace hs 0 150
Targetspace hs pval10.045929018789144
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:35
Sym Orf Description Function No All Z_score hyperg
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   40 54   NAN
PKC1 YBL105C Protein serine/threonine kinase essential for cell wall remodeling during growth...   38 102   0
RVS161 YCR009C Amphiphysin-like lipid raft protein; subunit of a complex (Rvs161p-Rvs167p) that...   34 140   0
CHS3 YBR023C Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to c... chitin synthase 3 34 93   NAN
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, requ... scaffold protein 34 41 -2.3759 NAN
CCW12 YLR110C Cell wall protein, mutants are defective in mating and agglutination, expression... cell wall mannoprotein 33 115   0
CWH41 YGL027C Processing alpha glucosidase I, ER type II integral membrane N-glycoprotein invo... glucosidase I 32 62   0
PCL2 YDL127W G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to... G1 cyclin 32 19   0
PCL1 YNL289W Pho85 cyclin of the Pcl1,2-like subfamily, involved in entry into the mitotic ce... G1 cyclin|associates with PHO85 32 25   0
CDC28 YBR160W Catalytic subunit of the main cell cycle cyclin-dependent kinase (CDK); alternat... cyclin-dependent protein kinase 31 110   0
MYO2 YOR326W One of two type V myosins, involved in polarized distribution of mitochondria; r... class V myosin 31 104   0
MID2 YLR332W O-glycosylated plasma membrane protein that acts as a sensor for cell wall integ...   31 46   0.005
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 30 140   0
YUR1 YJL139C Mannosyltransferase of the KTR1 family, involved in protein N-glycosylation; loc... mannosyltransferase 30 29   0
  YKL037W     30 12   0
KAR1 YNL188W Essential protein involved in karyogamy during mating and in spindle pole body d...   30 16   0
  YKL161C     30 5   0
CHS5 YLR330W Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p...   29 107 -3.7644 NAN
ROT2 YBR229C Glucosidase II catalytic subunit required for normal cell wall synthesis; mutati... glucosidase II 28 92 -4.1097 0.0001
TOR2 YKL203C PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha...   28 32   0
KRE11 YGR166W Protein involved in biosynthesis of cell wall beta-glucans; subunit of the TRAPP...   26 62   NAN
CDC53 YDL132W Cullin, structural protein of SCF complexes (which also contain Skp1p, Cdc34p, a...   24 24   0
RVS167 YDR388W Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) involved in reg... cytoskeletal protein (putative) 23 108 -8.3712 0
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   22 71 -5.3250 0.0003
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely... rho GTPase 22 8   0
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p), a membrane-associated co...   22 24   0
SKT5 YBL061C Activator of Chs3p (chitin synthase III), recruits Chs3p to the bud neck via int...   22 67   0.033
CDC15 YAR019C Protein kinase of the Mitotic Exit Network that is localized to the spindle pole... protein kinase domain 22 66   0
TPM1 YNL079C Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments... tropomyosin I 22 46   0.0058
CDC34 YDR054C Ubiquitin-conjugating enzyme or E2; together with Skp1p, Rbx1p, Cdc53p, and an F... ubiquitin-conjugating enzyme 22 58   0
CHS7 YHR142W Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p...   22 45   NAN
SIW14 YNL032W Tyrosine phosphatase that plays a role in actin filament organization and endocy... tyrosine phosphatase 22 16   0
MNN2 YBR015C Alpha-1,2-mannosyltransferase, responsible for addition of the first alpha-1,2-l... golgi alpha-1,2-mannosyltransferase (putative) 21 41   0
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that functions to modulate Rhop1 activi...   21 26   0.0021
MOB1 YIL106W Component of the mitotic exit network; associates with and is required for the a...   21 22   0

Service provided by the Mike Tyers Laboratory