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SONAR Targetspace for BERBERINE CHLORIDEZ-score WebGraph NB WebGraph
Targetspace hs 1051 535
Targetspace hs pval00.34666666666667
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:38
Sym Orf Description Function No All Z_score hyperg
PAF1 YBR279W RNA polymerase II-associated protein, defines a large complex that is biochemica...   12 51 -0.7499 0
RLM1 YPL089C MADS-box transcription factor, component of the protein kinase C-mediated MAP ki...   11 15   0.0524
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 11 39   0
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 11 25 -11.4640 NAN
MSG5 YNL053W Dual-specificity protein phosphatase required for maintenance of a low level of ... protein tyrosine phosphatase 10 16   0
BCK1 YJL095W Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinas... MEKK 10 143 -6.0816 0
MKK2 YPL140C Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... protein kinase 10 33   0
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   10 26 -8.7958 0.14
MKK1 YOR231W Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... MAP kinase kinase (MEK) 10 38 -5.1276 0.1393
PHO23 YNL097C Probable component of the Rpd3 histone deacetylase complex, involved in transcri...   9 36   0.1222
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for... MAP kinase 9 21   0
IRE1 YHR079C Serine-threonine kinase and endoribonuclease; transmembrane protein that initiat... endoribonuclease|serine-threonine kinase|transmembrane protein 9 95 -18.0446 0.0716
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which cataly... isocitrate dehydrogenase 1 alpha-4-beta-4 subunit 8 17   0
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golg... similar to Gcs1p and Sps18p|zinc finger protein 8 48   0.0871
PTC2 YER089C Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress ... protein phosphatase type 2C 8 15   0
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 8 24 0.1432 0
LYS12 YIL094C Homo-isocitrate dehydrogenase, an NAD-linked mitochondrial enzyme required for t... homo-isocitrate dehydrogenase 8 51   0
ADA2 YDR448W Transcription coactivator, component of the ADA and SAGA transcriptional adaptor... transcription factor 7 108   0
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   7 34   0
KIN2 YLR096W Serine/threonine protein kinase involved in regulation of exocytosis; localizes ...   7 109   0
STE20 YHL007C Signal transducing kinase of the PAK (p21-activated kinase) family, involved in ...   7 117   0
  YPL150W     6 52   0
RXT2 YBR095C Protein possibly involved in cell fusion and invasive growth   6 33   0.0114
CTR9 YOL145C Component of the Paf1p complex, which is a large complex that binds to and modul...   6 49   0.1388
USE1 YGL098W Essential SNARE protein localized to the ER, involved in retrograde traffic from...   6 19   0
CTI6 YPL181W Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p c...   6 47   0.0097
SIN3 YOL004W DNA binding subunit of Sin3p-Rpd3p histone deacetylase complex, involved in tran... DNA binding protein|involved in transcriptional regulation 6 75   0
EGD2 YHR193C Alpha subunit of the heteromeric nascent polypeptide-associated complex (NAC) in... GAL4 enhancer protein|nascent-polypeptide-associated complex human alpha NAC subunit homolog 6 33   0
SES1 YDR023W Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoac... serine-tRNA ligase 6 56   0
RTF1 YGL244W Subunit of the RNA polymerase II-associated Paf1 complex; directly or indirectly... nuclear protein 6 36   0.1343
PTC1 YDL006W Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by ...   6 31   0.0123
  YBR108W     6 38   0
DSK2 YMR276W Nuclear-enriched ubiquitin-like polyubiquitin-binding protein, required for spin... ubiquitin-like protein 6 37   0
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS), forms a complex with methionyl-tRNA synthetase...   6 83   0
ARB1 YER036C ATPase of the ATP-binding cassette (ABC) family involved in 40S and 60S ribosome... Shuttling protein, ATP binding cassette protein 6 74   0
KIC1 YHR102W Protein kinase of the PAK/Ste20 kinase family, required for cell integrity possi...   6 22   0
UME1 YPL139C Negative regulator of meiosis, required for repression of a subset of meiotic ge... transcriptional modulator 6 39   0.005
SDS3 YIL084C Component of the Rpd3p/Sin3p deacetylase complex required for its structural int...   6 33   0.0277

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