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SONAR Targetspace for BERBERINE CHLORIDEZ-score WebGraph NB WebGraph
Targetspace hs 1051 535
Targetspace hs pval00.34666666666667
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:37
Sym Orf Description Function No All Z_score hyperg
UBP14 YBR058C Ubiquitin-specific protease that specifically disassembles unanchored ubiquitin ... ubiquitin-specific protease 23 148   0.0144
MID2 YLR332W O-glycosylated plasma membrane protein that acts as a sensor for cell wall integ...   12 147   0.0079
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding and autopha... vesicle coat component 12 59   0
MIH1 YMR036C Protein tyrosine phosphatase involved in cell cycle control; regulates the phosp... protein phosphatase 12 61   0
HPT1 YDR399W Dimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation ... hypoxanthine guanine phosphoribosyltransferase 11 119   0
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation...   10 31   0.1342
ERV29 YGR284C Protein localized to COPII-coated vesicles, involved in vesicle formation and in... ER-Golgi transport vesicle protein 10 114   0
SEC13 YLR208W Component of both the Nup84 nuclear pore sub-complex and of the COPII complex (S... nuclear pore complex subunit|protein involved in release of transport vesicles from the ER 9 98   0
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 9 95   0
ALP1 YNL270C Basic amino acid transporter, involved in uptake of cationic amino acids basic amino acid permease 9 35   0
PTC2 YER089C Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress ... protein phosphatase type 2C 9 133   0
GPI17 YDR434W Transmembrane protein subunit of the glycosylphosphatidylinositol transamidase c... GPI transamidase component, human PIG-S homologue 8 24   0.0072
YSY6 YBR162W-A Protein whose expression suppresses a secretory pathway mutation in E. coli; has...   8 29   0
  YHR045W     8 22   0
SDP1 YIL113W Stress-inducible dual-specificity MAP kinase phosphatase, negatively regulates S...   8 13   0
ERP5 YHR110W Protein with similarity to Emp24p and Erv25p, member of the p24 family involved ... p24 protein involved in membrane trafficking 8 45   0
LST4 YKL176C Protein possibly involved in a post-Golgi secretory pathway; required for the tr...   8 128   0.0003
SSP120 YLR250W Protein of unknown function; green fluorescent protein (GFP)-fusion protein loca...   8 11   0
MSC2 YDR205W Member of the cation diffusion facilitator family, localizes to the endoplasmic ...   8 24   0
EPT1 YHR123W sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase; not essential ... sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase 8 69   0
EAP1 YKL204W eIF4E-associated protein, binds eIF4E and inhibits cap-dependent translation, al...   7 52   0.0003
PDR12 YPL058C Plasma membrane weak-acid-inducible ATP-binding cassette (ABC) transporter, requ... multidrug resistance transporter 7 70   0
PRE3 YJL001W 20S proteasome beta-type subunit, responsible for cleavage after acidic residues... 20S proteasome subunit 7 60   0
ERG1 YGR175C Squalene epoxidase, catalyzes the epoxidation of squalene to 2,3-oxidosqualene; ... squalene monooxygenase 7 36   0.0003
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for... MAP kinase 7 36   0
SPC2 YML055W Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyz... signal peptidase complex subunit|similar to mammalian protein SPC25 7 99   0.0061
  YLR064W     7 34   0
DIE2 YGR227W Dolichyl-phosphoglucose-dependent glucosyltransferase of the ER, functions in th... glucosyltransferase 6 98   0.0007
BIG1 YHR101C Integral membrane protein of the endoplasmic reticulum, required for normal cont...   6 63   0.0045
ERI1 YPL096C-A Endoplasmic reticulum membrane protein that binds to and inhibits GTP-bound Ras2...   6 48   0
SLN1 YIL147C Histidine kinase osmosensor that regulates a MAP kinase cascade; transmembrane p... histidine kinase osmosensor that regulates an osmosensing MAP kinase cascade|similar to bacterial two-component regulators 6 34   0
UFE1 YOR075W t-SNARE required for ER membrane fusion and vesicular traffic, integral membrane... t-SNARE (ER) 6 32   0
GAL7 YBR018C Galactose-1-phosphate uridyl transferase, synthesizes glucose-1-phosphate and UD... galactose-1-phosphate uridyl transferase 6 28   0
SES1 YDR023W Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoac... serine-tRNA ligase 6 61   0
SEC31 YDL195W Essential phosphoprotein component (p150) of the COPII coat of secretory pathway... COPII coat of secretory pathway vesicles component (p150) 6 51   0
PTC3 YBL056W Type 2C protein phosphatase; dephosphorylates Hog1p (see also Ptc2p) to limit ma... protein phosphatase type 2C 6 41   0
HRP1 YOL123W Subunit of cleavage factor I, a five-subunit complex required for the cleavage a... cleavage and polyadenylation factor CF I component involved in pre-mRNA 3--end processing 6 49   0.0003

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