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SONAR Targetspace for BERBERINE CHLORIDEZ-score WebGraph NB WebGraph
Targetspace hs 1051 535
Targetspace hs pval00.34666666666667
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:35
Sym Orf Description Function No All Z_score hyperg
RVS167 YDR388W Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) involved in reg... cytoskeletal protein (putative) 17 108 -35.3523 0
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   14 54   0
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, requ... scaffold protein 14 41 -12.6028 NAN
HOC1 YJR075W Alpha-1,6-mannosyltransferase involved in cell wall mannan biosynthesis; subunit... mannosyltransferase (putative) 13 64 -20.2351 0.0604
KRE11 YGR166W Protein involved in biosynthesis of cell wall beta-glucans; subunit of the TRAPP...   13 62   0
PKC1 YBL105C Protein serine/threonine kinase essential for cell wall remodeling during growth...   13 102   0.1158
RVS161 YCR009C Amphiphysin-like lipid raft protein; subunit of a complex (Rvs161p-Rvs167p) that...   13 140   0
YUR1 YJL139C Mannosyltransferase of the KTR1 family, involved in protein N-glycosylation; loc... mannosyltransferase 12 29   0.0001
CWH41 YGL027C Processing alpha glucosidase I, ER type II integral membrane N-glycoprotein invo... glucosidase I 12 62   0.1312
ROT1 YMR200W Protein that may be involved in cell wall function; mutations in rot1 cause cell... membrane protein (putative) 12 27   0
DIE2 YGR227W Dolichyl-phosphoglucose-dependent glucosyltransferase of the ER, functions in th... glucosyltransferase 12 48   0
CDC28 YBR160W Catalytic subunit of the main cell cycle cyclin-dependent kinase (CDK); alternat... cyclin-dependent protein kinase 12 110   0.0197
  YKL037W     11 12   0.0004
SEC66 YBR171W Non-essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with... glycoprotein complexed with Sec62p and Sec63p in the Sec63 complex, an integral endoplasmic reticulum membrane protein complex required for translocation of presecretory proteins 11 109 -0.6341 NAN
IKI3 YLR384C Subunit of RNA polymerase II elongator histone acetyltransferase complex, involv...   11 80 -1.2384 NAN
MID2 YLR332W O-glycosylated plasma membrane protein that acts as a sensor for cell wall integ...   11 46   0.004
SIW14 YNL032W Tyrosine phosphatase that plays a role in actin filament organization and endocy... tyrosine phosphatase 11 16   0
MNN2 YBR015C Alpha-1,2-mannosyltransferase, responsible for addition of the first alpha-1,2-l... golgi alpha-1,2-mannosyltransferase (putative) 11 41   0.0005
KAR9 YPL269W Karyogamy protein required for correct positioning of the mitotic spindle and fo...   11 82   0.0001
  YKL161C     10 5   0.1116
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation...   10 10   0.1342
RPI1 YIL119C Putative transcriptional regulator; overexpression suppresses the heat shock sen... ras inhibitor 10 9   0.0011
FPS1 YLL043W Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) fa... glycerol channel protein 10 28   0.0012
CLB4 YLR210W B-type cyclin involved in cell cycle progression; activates Cdc28p to promote th... B-type cyclin 10 28   0.1439
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly; serves as a K1 killer t...   10 119 -13.9976 0
BCK1 YJL095W Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinas... MEKK 9 89 -6.0816 0
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation...   9 31 -29.6983 0.1429
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alt... 1,3-beta-D-glucan synthase 9 126 -6.4928 0
CHS3 YBR023C Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to c... chitin synthase 3 9 93 -0.8408 0
HRD1 YOL013C Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradati...   9 61   0.0001
PTC2 YER089C Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress ... protein phosphatase type 2C 9 28   0
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase, associates with transcriptionally active...   8 60   0.006
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase; identified as a high-copy number suppre... type 2C protein phosphatase 8 4   0.1437
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding and autopha... vesicle coat component 8 14   0
ELP4 YPL101W Elongator protein, part of the HAP subcomplex of Elongator, which is a six-subun... RNA polymerase II Elongator protein subunit 8 80   0.0001

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