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SONAR Targetspace for BUTAMBENZ-score WebGraph NB WebGraph
Targetspace hs 250 109
Targetspace hs pval0.0394190871369290.70408163265306
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:36
Sym Orf Description Function No All Z_score hyperg
MYO2 YOR326W One of two type V myosins, involved in polarized distribution of mitochondria; r... class V myosin 17 104   0
RVS167 YDR388W Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) involved in reg... cytoskeletal protein (putative) 15 108 -4.9491 0
TPM1 YNL079C Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments... tropomyosin I 15 46   0
CCW12 YLR110C Cell wall protein, mutants are defective in mating and agglutination, expression... cell wall mannoprotein 15 115   0
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 15 145 -8.2399 NAN
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alt... 1,3-beta-D-glucan synthase 14 126 -11.8965 0
SMY1 YKL079W Protein that interacts with Myo2p, proposed to be involved in exocytosis; N-term... kinesin heavy chain homolog 14 29   0.0001
CHS5 YLR330W Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p...   14 107 -2.5502 0
MYO1 YHR023W Type II myosin heavy chain, required for wild-type cytokinesis and cell separati... class II myosin 12 64   0
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, requ... scaffold protein 11 41 -4.3347 NAN
  YKL161C     10 5   0.1116
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to p... G1 cyclin 10 110 -1.8664 0
RPI1 YIL119C Putative transcriptional regulator; overexpression suppresses the heat shock sen... ras inhibitor 10 9   0.0011
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   10 54   0
UBP3 YER151C Ubiquitin-specific protease that interacts with Bre5p to co-regulate anterograde... ubiquitin-specific protease 10 99   0.0002
CNB1 YKL190W Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulate... calcineurin regulatory B subunit|type 2B protein phosphatase 10 81 -1.0701 0
ARC40 YBR234C Essential subunit of the ARP2/3 complex, which is required for the motility and ...   10 44   NAN
FPS1 YLL043W Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) fa... glycerol channel protein 10 28   0.0012
KAR1 YNL188W Essential protein involved in karyogamy during mating and in spindle pole body d...   10 16   0.0029
  YKL037W     10 12   0.0015
MID2 YLR332W O-glycosylated plasma membrane protein that acts as a sensor for cell wall integ...   10 46   0.0018
RIM21 YNL294C Protein proposed to be involved in the response to alkaline pH; has similarity t... Unknown function 10 37   0
GSC2 YGR032W Catalytic subunit of 1,3-beta-glucan synthase, has similarity to an alternate ca... 1,3-beta-D-glucan synthase 9 9   0
CNA1 YLR433C Calcineurin A; one isoform (the other is CMP2) of the catalytic subunit of calci... calcineurin subunit A 9 12   0.0009
PCL1 YNL289W Pho85 cyclin of the Pcl1,2-like subfamily, involved in entry into the mitotic ce... G1 cyclin|associates with PHO85 9 25   0.1444
CHS6 YJL099W Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p...   9 54   NAN
ARP2 YDL029W Essential component of the Arp2/3 complex, which is a highly conserved actin nuc... actin related protein 9 99   NAN
ROT1 YMR200W Protein that may be involved in cell wall function; mutations in rot1 cause cell... membrane protein (putative) 8 27   0
VPS8 YAL002W Membrane-associated hydrophilic protein that interacts with the small GTPase, Vp... membrane-associated hydrophilic protein which contains a C-terminal cysteine-rich region that conforms to the H2 variant of the RING finger Zn2+ binding motif 8 38   0.1471
ERG11 YHR007C Lanosterol 14-alpha-demethylase, catalyzes the C-14 demethylation of lanosterol ... cytochrome P450 lanosterol 14a-demethylase 8 79   0.1044
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation...   8 31 -0.9555 0.1558
PCL2 YDL127W G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to... G1 cyclin 8 19   0.0044
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 8 140 -4.6570 0
SWF1 YDR126W Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on a...   8 48   0
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   8 71 -4.9906 0.1083
RIM101 YHL027W Transcriptional repressor involved in the response to pH; required for alkaline ...   8 65   0.0842

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