Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for PRUNETINZ-score WebGraph NB WebGraph
Targetspace hs 109 194
Targetspace hs pval0.30129870129870.20432692307692
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
SLA2 YNL243W Transmembrane actin-binding protein involved in membrane cytoskeleton assembly a... transmembrane protein 2 64   0.0304
MVP1 YMR004W Protein required for sorting proteins to the vacuole; overproduction of Mvp1p su...   2 16   0
GTR1 YML121W Cytoplasmic GTP binding protein and negative regulator of the Ran/Tc4 GTPase cyc... small GTPase (putative) 2 57   0.1539
SPC2 YML055W Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyz... signal peptidase complex subunit|similar to mammalian protein SPC25 2 45   0
SEL1 YML013W UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48...   2 86   0.2689
ATG8 YBL078C Protein required for autophagy; modified by the serial action of Atg4p, Atg7p, a... similar to LC3, a microtubule-associated protein from rat 2 20   0
UBX4 YMR067C UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48...   2 37   0.004
  YMR073C     2 23   0.0015
COG6 YNL041C Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   2 57   0
GOT1 YMR292W Evolutionarily conserved non-essential protein present in early Golgi cisternae ... membrane protein 2 34   0
SKY1 YMR216C SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabo...   2 97   0
HLJ1 YMR161W Co-chaperone for Hsp40p, anchored in the ER membrane; with its homolog Hdj1p pro...   2 102   0.0005
ERG2 YMR202W C-8 sterol isomerase, catalyzes the isomerization of the delta-8 double bond to ... C-8 sterol isomerase 2 109   0
APL2 YKL135C Beta-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; b... beta-adaptin|clathrin associated protein complex large subunit 2 19   0
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide ... Hsp70 family 2 80   0.0112
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 2 145 -6.0058 NAN
ERV14 YGL054C Protein localized to COPII-coated vesicles, involved in vesicle formation and in... 14 kDa protein found on ER-derived vesicles 2 76   0
RER1 YCL001W Protein involved in retention of membrane proteins, including Sec12p, in the ER;...   2 73   0.0004
ALG3 YBL082C Dolichol-P-Man dependent alpha(1-3) mannosyltransferase, involved in the synthes... Dol-P-Man dependent alpha(1-3) mannosyltransferase (putative) 2 42   0.0174
NPL4 YBR170C Endoplasmic reticulum and nuclear membrane protein, forms a complex with Cdc48p ...   2 26   0.0051
TIR3 YIL011W Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins... cell wall mannoprotein 2 3   0
SEC6 YIL068C Essential 88kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec1... exocyst complex component 2 43   0.0761
OPI3 YJR073C Phospholipid methyltransferase (methylene-fatty-acyl-phospholipid synthase), cat... unsaturated phospholipid N-methyltransferase 2 126   0
STE24 YJR117W Highly conserved zinc metalloprotease that functions in two steps of a-factor ma... zinc metallo-protease 2 55   0.2163
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   2 30   0.0653
HXT8 YJL214W Protein of unknown function with similarity to hexose transporter family members... hexose permease 2 13   0
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5... hydrophilic protein that is peripherally associated with the late Golgi and forms a stable complex with Vps52p and Vps54p 2 75   0.1924
ZAP1 YJL056C Zinc-regulated transcription factor, binds to zinc-responsive promoter elements ...   2 30   0
USA1 YML029W Protein that interacts in the two-hybrid system with the U1 snRNP-specific prote... pre-mRNA splicing factor (putative) 2 39   0
ALG6 YOR002W Glucosyltransferase, involved in transfer of oligosaccharides from dolichyl pyro... glucosyltransferase 2 78   0.0006
ALG12 YNR030W Alpha-1,6-mannosyltransferase localized to the ER; responsible for the addition ... mannosyltransferase 2 49   0.2114
ERV41 YML067C Protein localized to COPII-coated vesicles, forms a complex with Erv46p; involve...   1 13   0
FIS1 YIL065C Mitochondrial outer membrane protein involved in membrane fission, required for ...   1 7   0.0293
CCS1 YMR038C Copper chaperone for superoxide dismutase Sod1p, involved in oxidative stress pr... copper chaperone 1 129   0
GTR2 YGR163W Cytoplasmic GTP binding protein, negative regulator of the Ran/Tc4 GTPase cycle ... similar to Gtr1|small GTPase (putative) 1 16   0.0533
SEC14 YMR079W Phosphatidylinositol/phosphatidylcholine transfer protein involved in coordinate... phosphatidylcholine transfer protein|phosphatidylinositol transfer protein 1 139   0
SAC1 YKL212W Lipid phosphoinositide phosphatase of the ER and Golgi, involved in protein traf... phosphoinositide phosphatase 1 64   0
SYS1 YJL004C Integral membrane protein of the Golgi required for targeting of the Arf-like GT...   1 41   0
PEX28 YHR150W Peroxisomal integral membrane protein, involved in regulation of peroxisome size... peroxin 1 5   0.3207
MDV1 YJL112W Peripheral protein of the cytosolic face of the mitochondrial outer membrane, re...   1 4   0

Service provided by the Mike Tyers Laboratory