Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
VPS17 YOR132W Subunit of the membrane-associated retromer complex essential for endosome-to-Go...   6 21   0.0534
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   6 12   0.0049
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 6 56   0.0005
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in v... GTPase activating protein (GAP) 6 67 -1.1361 0
GET3 YDL100C ATPase, subunit of the GET complex; required for the retrieval of HDEL proteins ...   5 110   0.001
PKR1 YMR123W Protein of unknown function; overproduction confers resistance to Pichia farinos...   5 32   0
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleot...   5 66 -3.7532 0
MAK3 YPR051W Catalytic subunit of N-terminal acetyltransferase of the NatC type; required for... N-acetyltransferase 4 20   0.0043
ARL3 YPL051W GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to...   4 42 -2.6700 0
TFP1 YDL185W Vacuolar ATPase V1 domain subunit A containing the catalytic nucleotide binding ... protein with three regions (ABC) that are spliced to yield the extein AC and the intein B; AC is a 69K vacuolar (H+)-ATPase, and B is a 50K site-specfic endonuclease named VDE (PI-SceI) that is homologous to HO. Cleavage is meiosis-specific and induces ge|site-specific endonuclease VDE (PI-SceI)|vacuolar ATPase V1 domain subunit A (69 kDa) 4 65   0.0185
EGD1 YPL037C Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in pr... pol II transcribed genes regulator 4 8   0.0012
SLY1 YDR189W Hydrophilic protein involved in vesicle trafficking between the ER and Golgi; SM... t-SNARE-interacting protein that functions in ER-to-Golgi traffic 4 38   0.2027
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   4 23   0
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway, along with Nam7p an...   3 20   0.034
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT), catalyzes the first step in t... phosphatidyl-ethanolamine N-methyltransferase 3 33   0.0571
RPL2A YFR031C-A Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and ... ribosomal protein L2A (L5A) (rp8) (YL6) 3 9   0
VMA7 YGR020C Subunit F of the eight-subunit V1 peripheral membrane domain of vacuolar H+-ATPa... vacuolar ATPase V1 domain subunit F (14 kDa) 3 14   0.0737
SCS2 YER120W Integral ER membrane protein that regulates phospholipid metabolism via an inter...   3 38   0
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline... clathrin assembly complex beta adaptin component (putative) 3 10   0
SNF4 YGL115W Protein kinase activator found in a complex containing Snf1p and members of the ... associates with Snf1p 3 31   0
ZRT1 YGL255W High-affinity zinc transporter of the plasma membrane, responsible for the major...   3 7   0.232
SEC28 YIL076W Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein tr... epsilon-COP coatomer subunit 3 19   0
VMA10 YHR039C-A Vacuolar H+ ATPase subunit G of the catalytic (V1) sector, involved in vacuolar ... vacuolar ATPase V1 domain subunit G (13 kDa) 3 5   0
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   3 30   0.1228
GEF1 YJR040W Chloride channel localized to late- or post-Golgi vesicles, involved in iron met... transport protein involved in intracellular iron metabolism (putative) 3 10   0
TEF4 YKL081W Translation elongation factor EF-1 gamma translation elongation factor EF-1gamma 3 15   0.223
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in tr... v-SNARE 3 14   0.0538
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isome... cyclophilin 40|peptidyl-prolyl cis-trans isomerase (PPIase) 3 33   0.0895
VPS35 YJL154C Endosomal protein that is a subunit of the membrane-associated retromer complex ... retromer complex component 3 38 -0.3152 0.239
VMA22 YHR060W Integral membrane protein that is required for vacuolar H+-ATPase (V-ATPase) fun...   3 17   0.0874
  YIL039W     3 65   0
SBH1 YER087C-B Beta subunit of the Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p); involv... Sbh2p homolog 3 11   0
  YJL123C     3 30   0.0633
SYS1 YJL004C Integral membrane protein of the Golgi required for targeting of the Arf-like GT...   3 41   0
TLG1 YDR468C Essential t-SNARE that forms a complex with Tlg2p and Vti1p and mediates fusion ... tSNARE that affects a late Golgi compartment 3 6   0.0049
MAK10 YEL053C Non-catalytic subunit of N-terminal acetyltransferase of the NatC type, required...   3 17   0.0376
RER1 YCL001W Protein involved in retention of membrane proteins, including Sec12p, in the ER;...   3 73   0.0019
SRO9 YCL037C Cytoplasmic RNA-binding protein that associates with translating ribosomes; invo...   3 30   0.0065
MAK31 YCR020C-A Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; required...   3 5   0
USO1 YDL058W Essential protein involved in intracellular protein transport, coiled-coil prote... integrin analogue gene 3 21   0.0221

Service provided by the Mike Tyers Laboratory