Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for PREGNENOLONEZ-score WebGraph NB WebGraph
Targetspace hs 126 225
Targetspace hs pval0.0659574468085110.32539682539683
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:39
Sym Orf Description Function No All Z_score hyperg
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in v... GTPase activating protein (GAP) 10 67 -2.4392 0
VPS17 YOR132W Subunit of the membrane-associated retromer complex essential for endosome-to-Go...   10 21   0.0006
IMH1 YLR309C Protein involved in vesicular transport, mediates transport between an endosomal...   10 4   0.0157
ARL3 YPL051W GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to...   9 42 -4.5895 0
PKR1 YMR123W Protein of unknown function; overproduction confers resistance to Pichia farinos...   9 32   0
  ETG9627     8 5   0
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   8 12   0.0002
  YPR084W     8 4   0.0128
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane, converts p... phosphatidylserine decarboxylase 7 45   0.1624
  YMR010W     7 4   NAN
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex that functions in carboxy...   7 31   0.0067
  YOR112W     7 6   0.0714
PPG1 YNR032W Putative serine/threonine protein phosphatase, required for glycogen accumulatio...   7 6   0.1629
MAK3 YPR051W Catalytic subunit of N-terminal acetyltransferase of the NatC type; required for... N-acetyltransferase 7 20   0
MRL1 YPR079W Membrane protein with similarity to mammalian mannose-6-phosphate receptors, pos...   7 3   0.1577
DSS4 YPR017C Nucleotide release factor functioning in the post-Golgi secretory pathway, requi... GDP dissociation factor for Sec4p 7 14   0.1579
OXR1 YPL196W Protein of unknown function required for normal levels of resistance to oxidativ...   7 2   0.1502
EMP70 YLR083C Protein whose 24kDa cleavage product is found in endosome-enriched membrane frac...   7 7   0.011
  YPL105C     7 2   0
GMH1 YKR030W Golgi membrane protein of unknown function, interacts with Gea1p and Gea2p; requ...   7 5   0.1522
ENT4 YLL038C Protein of unknown function, contains an N-terminal epsin-like domain   7 4   0.0046
VPS30 YPL120W Protein that forms a membrane-associated complex with Apg14p that is essential f...   7 25   0.0942
SFT2 YBL102W Non-essential tetra-spanning membrane protein found mostly in the late Golgi, ca...   7 8   NAN
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   7 30   0.1286
RUD3 YOR216C Golgi matrix protein involved in the structural organization of the cis-Golgi; i...   7 100   0
GOS1 YHL031C v-SNARE protein involved in Golgi transport, homolog of the mammalian protein GO...   7 56   0
SEC28 YIL076W Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein tr... epsilon-COP coatomer subunit 7 19   0
  YDR107C     7 5   0.1632
ENT5 YDR153C Protein containing an N-terminal epsin-like domain involved in clathrin recruitm...   7 8   0.1234
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in tr... v-SNARE 7 14   0.1648
TVP15 YDR100W Integral membrane protein localized to late Golgi vesicles along with the v-SNAR... integral membrane protein 7 3   NAN
TEF4 YKL081W Translation elongation factor EF-1 gamma translation elongation factor EF-1gamma 7 15   0.0449
RIM15 YFL033C Glucose-repressible protein kinase involved in signal transduction during cell p... trehalose-associated protein kinase related to S. pombe cek1+ 7 20   0.1613
RAV2 YDR202C Subunit of RAVE (Rav1p, Rav2p, Skp1p), a complex that associates with the V1 dom...   7 7   0.1636
  YEL043W     7 4   0
MAK31 YCR020C-A Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; required...   7 5   0
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 7 56   0.0014
SNF4 YGL115W Protein kinase activator found in a complex containing Snf1p and members of the ... associates with Snf1p 6 31   0
APL5 YPL195W Delta adaptin-like subunit of the clathrin associated protein complex (AP-3); fu... clathrin assembly complex AP-3 adaptin component delta-like subunit 6 9   0

Service provided by the Mike Tyers Laboratory