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SONAR Targetspace for PREGNENOLONEZ-score WebGraph NB WebGraph
Targetspace hs 126 225
Targetspace hs pval0.0659574468085110.32539682539683
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:39
Sym Orf Description Function No All Z_score hyperg
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleot...   10 10 -12.5846 0
YIP3 YNL044W Protein localized to COPII vesicles, proposed to be involved in ER to Golgi tran...   9 43   NAN
GDI1 YER136W GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by r... GDP dissociation inhibitor 8 25   0
GYP6 YJL044C GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved... GTPase activating protein (GAP) for Ypt6 8 13   0
MDR1 YGR100W Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p, Ypt31... GTPase activating protein (GAP) for Ypt6 8 13   0
YEF3 YLR249W Translational elongation factor, stimulates the binding of aminoacyl-tRNA (AA-tR... Translation elongation factor 3 (EF-3) 6 94   0
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network; forms heterod...   6 14 -5.9575 0
SGF73 YGL066W Probable 73 kDa subunit of SAGA histone acetyltransferase complex Probable 73KkDa Subunit of SAGA histone acetyltransferase complex 5 57   0.0221
COG6 YNL041C Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   5 31   0
VPS54 YDR027C Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5...   4 22   0
NGG1 YDR176W Transcriptional regulator involved in glucose repression of Gal4p-regulated gene... genetic and mutant analyses suggest that Ngg1p (Ada3p) is part of two transcriptional adaptor/HAT (histone acetyltransferase complexes, the 0.8 MD ADA complex and the 1.8 MD SAGA complex|transcription factor 4 65   0.0011
CDC73 YLR418C Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rt...   4 61 -5.2513 0
YIP4 YGL198W Protein that interacts with Rab GTPases; computational analysis of large-scale p...   4 26   0
RIX7 YLL034C Putative ATPase of the AAA family, required for export of pre-ribosomal large su...   4 60   0
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex, involved in proper assem... histone acetyltransferase SAGA complex member|transcription factor 4 70   0.1585
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II tran...   4 84   0.0004
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes, involved in transcription initiati... TATA-binding protein-associated-factor 4 102   0
ACO1 YLR304C Aconitase, required for the tricarboxylic acid (TCA) cycle and also independentl... aconitase 4 28   0
UBP8 YMR223W Ubiquitin-specific protease that is a component of the SAGA (Spt-Ada-Gcn5-Acetyl...   4 49 -1.4922 0.174
TAF10 YDR167W Subunit (145 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II tra... TFIID subunit 4 82   0.0001
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p, involved in nuclear transport GTPase activating protein (GAP) for Gsp1p 4 27   0
MRS6 YOR370C Rab escort protein, forms a complex with the Ras-like small GTPase Ypt1p that is... rab geranylgeranyltransferase regulatory subunit 4 22   0.0002
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5... hydrophilic protein that is peripherally associated with the late Golgi and forms a stable complex with Vps52p and Vps54p 4 18   0.0151
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   4 45   0
YIP1 YGR172C Integral membrane protein required for the biogenesis of ER-derived COPII transp...   4 28   0.0164
YOP1 YPR028W Membrane protein that interacts with Yip1p to mediate membrane traffic; overexpr...   4 17   0
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II tran... TFIID subunit 3 74   0.1893
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II t... TFIID subunit 3 97   0.1553
SGF29 YCL010C SaGa associated Factor 29kDa; Probable 29kKDa Subunit of SAGA histone acetyltran... Probable 29kKDa Subunit of SAGA histone acetyltransferase complex 3 38   0.016
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes; interacts with aci... ATM/Mec1/TOR1/TOR2-related|NuA4 complex component 3 93   0
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex, regulates transcript...   3 39   0.0769
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex, which is an evoluti... pyruvate dehydrogenase beta subunit (E1 beta) 3 31   0.0623
LSM2 YBL026W Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either L... snRNA-associated protein, Sm class 3 101   0
ZUO1 YGR285C Cytosolic ribosome-associated chaperone that acts, together with Ssz1p and the S... zuotin, Z-DNA binding protein (putative) 3 50   0.0001
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5...   3 12   0.0028
HSP104 YLL026W Heat shock protein that cooperates with Ydj1p (Hsp40) and Ssa1p (Hsp70) to refol... heat shock protein 104 3 58 -5.0369 0
YIF1 YNL263C Integral membrane protein required for the fusion of ER-derived COPII transport ...   3 39   0
MSB4 YOL112W GTPase-activating protein of the Ras superfamily that acts primarily on Sec4p, l...   3 11   0
MSB3 YNL293W GTPase-activating protein for Sec4p and several other Rab GTPases, regulates exo... GTPase activating protein (GAP) for Ypt6 3 27   0

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