Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for PREGNENOLONEZ-score WebGraph NB WebGraph
Targetspace hs 126 225
Targetspace hs pval0.0659574468085110.32539682539683
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:28
Sym Orf Description Function No All Z_score hyperg
YIP3 YNL044W Protein localized to COPII vesicles, proposed to be involved in ER to Golgi tran...   16 96   NAN
MRL1 YPR079W Membrane protein with similarity to mammalian mannose-6-phosphate receptors, pos...   14 55   0.0025
APS3 YJL024C Small subunit of the clathrin-associated adaptor complex AP-3, which is involved...   13 97   0
ENT5 YDR153C Protein containing an N-terminal epsin-like domain involved in clathrin recruitm...   13 112   0.0014
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   13 94   NAN
SYG1 YIL047C Plasma membrane protein of unknown function; truncation and overexpression suppr... plasma membrane protein 12 46   0
ESC8 YOL017W Protein involved in telomeric and mating-type locus silencing, interacts with Si...   12 51   NAN
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapam... peptidyl-prolyl cis-trans isomerase (PPIase) 12 131   0
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway, along with Nam7p an...   12 134   0.0403
  YEL043W     12 70   0
SAP190 YKR028W Protein that forms a complex with the Sit4p protein phosphatase and is required ... type 2A-related protein phosphatase 12 104   0
EDC1 YGL222C RNA-binding protein, activates mRNA decapping directly by binding to the mRNA su...   11 28   0
IMH1 YLR309C Protein involved in vesicular transport, mediates transport between an endosomal...   11 24   0.0271
RAV2 YDR202C Subunit of RAVE (Rav1p, Rav2p, Skp1p), a complex that associates with the V1 dom...   11 103   0.0438
TVP15 YDR100W Integral membrane protein localized to late Golgi vesicles along with the v-SNAR... integral membrane protein 11 85   NAN
DBR1 YKL149C RNA lariat debranching enzyme, involved in intron turnover; required for efficie... RNA lariat debranching enzyme 10 56   0
VPS30 YPL120W Protein that forms a membrane-associated complex with Apg14p that is essential f...   10 109   0.011
GYP6 YJL044C GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved... GTPase activating protein (GAP) for Ypt6 10 107   0
MVP1 YMR004W Protein required for sorting proteins to the vacuole; overproduction of Mvp1p su...   10 89   0
MUD1 YBR119W U1 snRNP A protein, homolog of human U1-A; involved in nuclear mRNA splicing U1 snRNP A protein 10 109   0
QCR6 YFR033C Subunit 6 of the ubiquinol cytochrome-c reductase complex, which is a component ... ubiquinol cytochrome C oxidoreductase subunit 6 (17 kDa) 10 60   0
VAM10 YOR068C Protein involved in vacuole morphogenesis; acts at an early step of homotypic va... Required for normal tethering of vacuoles prior to fusion. 10 144   0.0009
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline... clathrin assembly complex beta adaptin component (putative) 10 98   0
FAR11 YNL127W Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway ...   10 104   0.0043
GEF1 YJR040W Chloride channel localized to late- or post-Golgi vesicles, involved in iron met... transport protein involved in intracellular iron metabolism (putative) 9 83   0
NAM2 YLR382C Mitochondrial leucyl-tRNA synthetase, also has a direct role in splicing of seve... LeuRS|leucine-tRNA ligase 9 26   0
YEF3 YLR249W Translational elongation factor, stimulates the binding of aminoacyl-tRNA (AA-tR... Translation elongation factor 3 (EF-3) 9 107   0
EGD1 YPL037C Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in pr... pol II transcribed genes regulator 9 80   0

Service provided by the Mike Tyers Laboratory