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SONAR Targetspace for PENTAMIDINE ISETHIONATEZ-score WebGraph NB WebGraph
Targetspace hs 139 182
Targetspace hs pval0.136054421768710.041580041580042
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:39
Sym Orf Description Function No All Z_score hyperg
GCN5 YGR252W Histone acetyltransferase, acetylates lysine 14 on histone H3; catalytic subunit... histone acetyltransferase 12 119 -3.0996 0.0104
PTC2 YER089C Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress ... protein phosphatase type 2C 8 15   0
IRE1 YHR079C Serine-threonine kinase and endoribonuclease; transmembrane protein that initiat... endoribonuclease|serine-threonine kinase|transmembrane protein 8 95 -6.0346 0.111
KAR2 YJL034W ATPase involved in protein import into the ER, also acts as a chaperone to media... HSP70 family|mammalian BiP (GRP78 or HSPA5) homolog 8 58   0
ARB1 YER036C ATPase of the ATP-binding cassette (ABC) family involved in 40S and 60S ribosome... Shuttling protein, ATP binding cassette protein 7 74   0
SES1 YDR023W Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoac... serine-tRNA ligase 6 56   0
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golg... similar to Gcs1p and Sps18p|zinc finger protein 6 48   0.0344
ADA2 YDR448W Transcription coactivator, component of the ADA and SAGA transcriptional adaptor... transcription factor 6 108   0.0003
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex, a histone... Ada/Gcn5 protein complex member|transcription factor 6 49   0.0004
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex, involved in maintaining ... histone acetyltransferase SAGA complex member|transcription factor 6 52   0
VHS2 YIL135C Cytoplasmic protein of unknown function; identified as a high-copy suppressor of...   5 19   0
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS), forms a complex with methionyl-tRNA synthetase...   5 83   0
  YDR134C     5 16   0.0796
YAP6 YDR259C Putative basic leucine zipper (bZIP) transcription factor; overexpression increa...   5 22   0
  YBR108W     5 38   0
FRT2 YAL028W Tail-anchored endoplasmic reticulum membrane protein, interacts with homolog Frt...   5 35   0
PTC1 YDL006W Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by ...   5 31   0.0051
BDF2 YDL070W Protein involved in transcription initiation at TATA-containing promoters; assoc... BDF1 homolog|bromodomain protein 5 35   0
  YDL186W     5 5   0
SAS10 YDL153C Component of the small (ribosomal) subunit (SSU) processosome required for pre-1... U3 snoRNP protein 5 51   0
KKQ8 YKL168C Putative serine/threonine protein kinase with unknown cellular role   5 35   0
PRM10 YJL108C Pheromone-regulated protein, predicted to have 5 transmembrane segments   5 6   0
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p; required for recycling Golgi ... cysteine rich putative zinc finger essential for function|hydrophilic protein 5 25   0
  YNL284C-A     5 19   0
  YNR047W     5 25   0
RET1 YOR207C Second-largest subunit of RNA polymerase III, which is responsible for the trans...   5 52   0.1708
MTW1 YAL034W-A Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p...   5 50   0
  YPL257W-A     5 15   0
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p, located on cyto... GDP/GTP exchange factor 5 69   0
MLF3 YNL074C Serine-rich protein of unknown function; overproduction suppresses the growth in...   5 16   0
  YML045W-A     5 16   0
SSK1 YLR006C Cytoplasmic response regulator, part of a two-component signal transducer that m... two-component signal transducer that with Sln1p regulates osmosensing MAP kinase cascade(suppressor of sensor kinase) 5 18   0
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase, catalyzes the dephosph... phosphatidate phosphohydrolase 5 42   0
  YMR184W     5 19   0
  YMR295C     5 9   0
RNT1 YMR239C RNAase III; cleaves a stem-loop structure at the 3- end of U2 snRNA to ensure fo... ribonuclease III 5 30   0
  YML037C     5 29   0
ARX1 YDR101C Protein associated with the ribosomal export complex   5 102 -6.1837 0.0001
  YLR257W     4 18   0

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