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SONAR Targetspace for PENTAMIDINE ISETHIONATEZ-score WebGraph NB WebGraph
Targetspace hs 139 182
Targetspace hs pval0.136054421768710.041580041580042
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:31
Sym Orf Description Function No All Z_score hyperg
SEC13 YLR208W Component of both the Nup84 nuclear pore sub-complex and of the COPII complex (S... nuclear pore complex subunit|protein involved in release of transport vesicles from the ER 9 98   0
ATF2 YGR177C Alcohol acetyltransferase, may play a role in steroid detoxification; forms vola... alcohol acetyltransferase 8 29   0.0001
GPI17 YDR434W Transmembrane protein subunit of the glycosylphosphatidylinositol transamidase c... GPI transamidase component, human PIG-S homologue 8 24   0.0072
  YHR045W     8 22   0
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding and autopha... vesicle coat component 8 59   0
SSP120 YLR250W Protein of unknown function; green fluorescent protein (GFP)-fusion protein loca...   8 11   0
ERP5 YHR110W Protein with similarity to Emp24p and Erv25p, member of the p24 family involved ... p24 protein involved in membrane trafficking 8 45   0
BIG1 YHR101C Integral membrane protein of the endoplasmic reticulum, required for normal cont...   8 63   0.0001
SEC12 YNR026C Guanine nucleotide exchange factor (GEF); glycosylated integral membrane protein... guanine nucleotide exchange factor for Sar1p 8 51   0
YSY6 YBR162W-A Protein whose expression suppresses a secretory pathway mutation in E. coli; has...   8 29   0
ARB1 YER036C ATPase of the ATP-binding cassette (ABC) family involved in 40S and 60S ribosome... Shuttling protein, ATP binding cassette protein 7 75   0
ERV29 YGR284C Protein localized to COPII-coated vesicles, involved in vesicle formation and in... ER-Golgi transport vesicle protein 7 114   0.0001
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis, ind... phosphofructokinase alpha subunit 7 128   0
SEC62 YPL094C Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec... ER protein translocation apparatus membrane component 7 95   0
  YNL224C     7 55   0.02
  YLR064W     7 34   0
ERG1 YGR175C Squalene epoxidase, catalyzes the epoxidation of squalene to 2,3-oxidosqualene; ... squalene monooxygenase 7 36   0.0003
SCJ1 YMR214W One of several homologs of bacterial chaperone DnaJ, located in the ER lumen whe... DnaJ homolog 7 119   0
EPT1 YHR123W sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase; not essential ... sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase 6 69   0
DIE2 YGR227W Dolichyl-phosphoglucose-dependent glucosyltransferase of the ER, functions in th... glucosyltransferase 6 98   0.0007
SES1 YDR023W Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoac... serine-tRNA ligase 6 61   0
PTC2 YER089C Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress ... protein phosphatase type 2C 6 133   0
OST1 YJL002C Alpha subunit of the oligosaccharyltransferase complex of the ER lumen, which ca... 64 kDa, alpha subunit of oligosaccharyltransferase complex; homologous to mammalian ribophorin I 6 92   0
PTP1 YDL230W Phosphotyrosine-specific protein phosphatase that dephosphorylates a broad range... phosphotyrosine-specific protein phosphatase 6 66   0
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of the ER membrane, catalyzes th... dolichol phosphate mannose synthase 6 65   0
ALG12 YNR030W Alpha-1,6-mannosyltransferase localized to the ER; responsible for the addition ... mannosyltransferase 6 100   0.0006
DSL1 YNL258C Endoplasmic reticulum (ER)-localized peripheral membrane protein required for Go...   6 34   0.0635
HEM1 YDR232W 5-aminolevulinate synthase, catalyzes the first step in the heme biosynthetic pa... 5-aminolevulinate synthase 5 13   0
ROX1 YPR065W Heme-dependent repressor of hypoxic genes; contains an HMG domain that is respon... HMG-domain site-specific DNA binding protein. 5 59   0
RPT4 YOR259C One of six ATPases of the 19S regulatory particle of the 26S proteasome involved... 26S proteasome cap subunit component|ATPase 5 135   0
  YPL257W-A     5 15   0

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