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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   6 12   0.0049
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 4 56   0
MAF1 YDR005C Negative regulator of RNA polymerase III; component of several signaling pathway...   4 50   0.0157
DCR2 YLR361C Putative phosphoesterase that functions as a dosage-dependent positive regulator...   4 19   0
SEC18 YBR080C ATPase required for the release of Sec17p during the -priming- step in homotypic... ATPase|NSF|protein involved in protein transport between ER and Golgi 4 33   0.121
MVP1 YMR004W Protein required for sorting proteins to the vacuole; overproduction of Mvp1p su...   3 16   0
  YMR010W     3 4   0
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane, converts p... phosphatidylserine decarboxylase 3 45   0.0619
  YEL043W     3 4   0
  YDR266C     3 6   0
SEC20 YDR498C Membrane glycoprotein v-SNARE involved in retrograde transport from the Golgi to... v-SNARE 3 9   0.1012
SBH1 YER087C-B Beta subunit of the Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p); involv... Sbh2p homolog 3 11   0
SED5 YLR026C cis-Golgi t-SNARE syntaxin required for vesicular transport between the ER and t... syntaxin family 3 20   0.0017
EMP70 YLR083C Protein whose 24kDa cleavage product is found in endosome-enriched membrane frac...   3 7   0.2319
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   3 30   0.1228
SEC27 YGL137W Essential beta--coat protein of the COPI coatomer, involved in ER-to-Golgi and G... yeast coatomer beta--subunit 3 14   0
TEF4 YKL081W Translation elongation factor EF-1 gamma translation elongation factor EF-1gamma 3 15   0.223
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in tr... v-SNARE 3 14   0.0538
INO4 YOL108C Transcription factor required for derepression of inositol-choline-regulated gen... basic helix-loop-helix (bHLH) protein 3 10   0
ENT4 YLL038C Protein of unknown function, contains an N-terminal epsin-like domain   3 4   0.208
GMH1 YKR030W Golgi membrane protein of unknown function, interacts with Gea1p and Gea2p; requ...   3 5   0.0261
  YOR112W     3 6   0.1947
MRL1 YPR079W Membrane protein with similarity to mammalian mannose-6-phosphate receptors, pos...   3 3   0.0757
SEC23 YPR181C GTPase-activating protein; component of the Sec23p-Sec24p heterodimeric complex ... GTPase activating protein (GAP) 3 30   0.0077
RER1 YCL001W Protein involved in retention of membrane proteins, including Sec12p, in the ER;...   3 73   0.0019
ENT5 YDR153C Protein containing an N-terminal epsin-like domain involved in clathrin recruitm...   3 8   0.1301
  ETG9627     3 5   0
ATG20 YDL113C Protein required for transport of aminopeptidase I (Lap4p) through the cytoplasm... PX domain-containing protein that binds Apg17 and Cvt13, and is required for import of precursor Ape1. 3 6   0
GAP1 YKR039W General amino acid permease; localization to the plasma membrane is regulated by... general amino acid permease 3 41   0
YIP1 YGR172C Integral membrane protein required for the biogenesis of ER-derived COPII transp...   3 22   0.0657
SFT2 YBL102W Non-essential tetra-spanning membrane protein found mostly in the late Golgi, ca...   3 8   0
TVP15 YDR100W Integral membrane protein localized to late Golgi vesicles along with the v-SNAR... integral membrane protein 3 3   0
MAK31 YCR020C-A Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; required...   3 5   0
USO1 YDL058W Essential protein involved in intracellular protein transport, coiled-coil prote... integrin analogue gene 3 21   0.0221
  YDR107C     3 5   0.0447
RET3 YPL010W Zeta subunit of the coatomer complex (COPI), which coats Golgi-derived transport... vesicle coat component 3 2   0.0055
  YPL105C     3 2   0
OXR1 YPL196W Protein of unknown function required for normal levels of resistance to oxidativ...   3 2   0.0904
NTO1 YPR031W Component of the histone acetyltransferase complex HAT complex component 3 10   0.0001
DSS4 YPR017C Nucleotide release factor functioning in the post-Golgi secretory pathway, requi... GDP dissociation factor for Sec4p 3 14   0.0751

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