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SONAR Targetspace for THIORIDAZINE HYDROCHLORIDEZ-score WebGraph NB WebGraph
Targetspace hs 402 0
Targetspace hs pval0.0481171548117151
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:36
Sym Orf Description Function No All Z_score hyperg
PPH21 YDL134C Catalytic subunit of protein phosphatase 2A, functionally redundant with Pph22p;...   9 129 -33.4499 0
ARF2 YDL137W ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of... ADP-ribosylation factor 2 7 79   0.1633
MIH1 YMR036C Protein tyrosine phosphatase involved in cell cycle control; regulates the phosp... protein phosphatase 7 61   0.0094
BOI2 YER114C Protein implicated in polar growth, functionally redundant with Boi1p; interacts...   7 81   0
PET122 YER153C Specific translational activator for the COX3 mRNA that acts together with Pet54... translational activator of cytochrome C oxidase subunit III 6 121   0.0286
CIN4 YMR138W GTP-binding protein involved in beta-tubulin (Tub2p) folding; isolated as mutant... GTP-binding protein 6 90   0
ATG8 YBL078C Protein required for autophagy; modified by the serial action of Atg4p, Atg7p, a... similar to LC3, a microtubule-associated protein from rat 6 127   0
NNF2 YGR089W Protein that exhibits physical and genetic interactions with Rpb8p, which is a s...   5 90   0
KAR9 YPL269W Karyogamy protein required for correct positioning of the mitotic spindle and fo...   5 136   0
PRE1 YER012W 20S proteasome beta-type subunit; localizes to the nucleus throughout the cell c... 22.6 kDa proteasome subunit 5 144   0
SCL1 YGL011C Alpha subunit of the 20S core complex of the 26S proteasome involved in the degr... proteasome subunit YC7alpha/Y8 (protease yscE subunit 7) 5 81   0
MNN9 YPL050C Subunit of Golgi mannosyltransferase complex also containing Anp1p, Mnn10p, Mnn1... required for complex glycosylation 5 27   0
LEM3 YNL323W Membrane protein of the plasma membrane and ER, involved in translocation of pho... membrane glycoprotein 5 113   0.0004
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope, connects the nuclear p... colied-coil protein (putative), similar to myosin and TPR 5 109   0
ADE3 YGR204W Cytoplasmic trifunctional enzyme C1-tetrahydrofolate synthase, involved in singl... C1-tetrahydrofolate synthase 5 30   0
RPL22A YLR061W Protein component of the large (60S) ribosomal subunit, has similarity to Rpl22B... ribosomal protein L22A (L1c) (rp4) (YL31) 5 102   0
RPL1B YGL135W N-terminally acetylated protein component of the large (60S) ribosomal subunit, ... ribosomal protein L1B 5 132   0
PRE2 YPR103W 20S proteasome beta-type subunit, responsible for the chymotryptic activity of t... proteasome subunit 4 86   0.0041
DSL1 YNL258C Endoplasmic reticulum (ER)-localized peripheral membrane protein required for Go...   4 34   0.1912
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase involved in fatty acid biosynt...   4 124   0
IPT1 YDR072C Inositolphosphotransferase 1, involved in synthesis of mannose-(inositol-P)2-cer... inositolphosphotransferase 1 4 66   0.0004
DNM1 YLL001W Dynamin-related GTPase required for mitochondrial fission and the maintenance of... similar to dynamin GTPase 4 97 -1.4465 0.0493
APL2 YKL135C Beta-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; b... beta-adaptin|clathrin associated protein complex large subunit 4 80   0
RPT1 YKL145W One of six ATPases of the 19S regulatory particle of the 26S proteasome involved... 26S protease subunit component (putative)|ATPase 4 139   0
EAP1 YKL204W eIF4E-associated protein, binds eIF4E and inhibits cap-dependent translation, al...   4 52   0.0347
AME1 YBR211C Essential kinetochore protein associated with microtubules and spindle pole bodi... microtubule stability regulator 4 92   0
KEX1 YGL203C Protease involved in the processing of killer toxin and alpha factor precursor; ... protease|similar to carboxypeptidase B 4 113   0.0347
GEA2 YEL022W Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved... ARF GTP/GDP exchange factor 4 38   0.1894
  YGR125W     4 108   0.0353
GTT1 YIR038C ER associated glutathione S-transferase capable of homodimerization; expression ... glutathione transferase 4 90   0
YBP2 YGL060W Protein with a role in resistance to oxidative stress; has similarity to Ybp1p, ...   4 58   0.034
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer, involved in ER-to-Golgi protei... yeast coatomer subunit 4 51   0
CYS3 YAL012W Cystathionine gamma-lyase, catalyzes one of the two reactions involved in the tr... cystathionine gamma-lyase 4 100   0
FLC2 YAL053W Putative protein of unknown function; green fluorescent protein (GFP)-fusion pro...   4 55   0.0055
FMP45 YDL222C Integral membrane protein localized to mitochondria (untagged protein) and eisos... integral membrane protein 4 77   0.0022
SPI1 YER150W GPI-anchored, serine/threonine rich cell wall protein of unknown function; basal...   4 24   0

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