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SONAR Targetspace for PYRVINIUM PAMOATEZ-score WebGraph NB WebGraph
Targetspace hs 353 541
Targetspace hs pval0.0459290187891440
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:37
Sym Orf Description Function No All Z_score hyperg
EGD1 YPL037C Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in pr... pol II transcribed genes regulator 4 80   0.0012
IOC4 YMR044W Member of a complex (Isw1b) with Isw1p and Ioc2p that exhibits nucleosome-stimul...   4 126   0.0055
TUF1 YOR187W Mitochondrial translation elongation factor Tu; comprises both GTPase and guanin... translation elongation factor Tu, mitochondrial 4 61   0
FIR1 YER032W Protein involved in 3- mRNA processing, interacts with Ref2p; potential Cdc28p s... participant in 3- mRNA processing (putative) 4 61   0.0025
SPT6 YGR116W Essential protein that interacts with histones and is involved in nucleosome dis... interacts with histones, primarily histone H3, possesses nucleosome assembly activity|transcriptional regulator 4 66   0.1189
NOT5 YPR072W Subunit of the CCR4-NOT complex, which is a global transcriptional regulator wit... NOT complex member, a global negative regulator of transcription 4 62   0.035
PLB3 YOL011W Phospholipase B (lysophospholipase) involved in phospholipid metabolism; hydroly... phospholipase B (lysophospholipase) 4 52   0
RPA135 YPR010C RNA polymerase I subunit A135 RNA polymerase I subunit 4 96   0.0016
RPA190 YOR341W RNA polymerase I subunit; largest subunit of RNA polymerase I RNA polymerase I subunit 4 94   0
CDC39 YCR093W Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA l... transcriptional regulator 4 78   0.0169
  YCR061W     3 62   0
VPH2 YKL119C Integral membrane protein required for vacuolar H+-ATPase (V-ATPase) function, a... 25.2 kDa protein involved in assembly of vacuolar H(+) ATPase 3 103   0
FOB1 YDR110W Nucleolar protein required for DNA replication fork blocking and recombinational... DNA replication fork blocking protein 3 65   0.2078
VID24 YBR105C Peripheral membrane protein located at Vid (vacuole import and degradation) vesi... peripheral vesicle membrane protein 3 110   0
GLK1 YCL040W Glucokinase, catalyzes the phosphorylation of glucose at C6 in the first irrever... glucokinase 3 24   0.1387
DLD2 YDL178W D-lactate dehydrogenase, located in the mitochondrial matrix   3 12   0
ARO2 YGL148W Bifunctional chorismate synthase and flavin reductase, catalyzes the conversion ... chorismate synthase 3 148   0.0002
SPC98 YNL126W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts... gamma-tubulin complex component 3 24   0.0047
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3... histone acetyltransferase complex component 3 49   0.0092
  YMR247C     3 21   0.1737
EDS1 YBR033W Non-essential protein of unknown function   3 65   0
REF2 YDR195W RNA-binding protein involved in the cleavage step of mRNA 3--end formation prior... RNA-binding protein 3 65 7.3221 0.0016
HAL1 YPR005C Cytoplasmic protein involved in halotolerance; decreases intracellular Na+ (via ... polar 32 kDa cytoplasmic protein 3 9   0.0115
  YPR084W     3 27   0.0001
DEF1 YKL054C RNAPII degradation factor, forms a complex with Rad26p in chromatin, enables ubi... Rad26-interacting protein 3 62   0
CDC36 YDL165W Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA l... transcriptional regulator 3 89   0.0888
CYB5 YNL111C Cytochrome b5, involved in the sterol and lipid biosynthesis pathways; required ... cytochrome b5 3 60   0.0619
TRP2 YER090W Anthranilate synthase, catalyzes the initial step of tryptophan biosynthesis, fo... anthranilate synthase component I 3 76   0
VPS45 YGL095C Protein of the Sec1p/Munc-18 family, essential for vacuolar protein sorting; req...   3 70   0.184
COX7 YMR256C Subunit VII of cytochrome c oxidase, which is the terminal member of the mitocho... cytochrome c oxidase subunit VII 3 125   0
DHH1 YDL160C Cytoplasmic DExD/H-box helicase, stimulates mRNA decapping, coordinates distinct...   3 106   0.0946
VPS20 YMR077C Myristoylated subunit of ESCRTIII, the endosomal sorting complex required for tr...   3 64   0.0004
LEU1 YGL009C Isopropylmalate isomerase, catalyzes the second step in the leucine biosynthesis... isopropylmalate isomerase 3 32   0
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit   2 35   0
  YOL092W     2 42   0
ATP18 YML081C-A Subunit of the mitochondrial F1F0 ATP synthase, which is a large enzyme complex ... ATP synthase associated protein 2 124   0
RGT1 YKL038W Glucose-responsive transcription factor that regulates expression of several glu... transcriptional activator|transcriptional repressor 2 45   0

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