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SONAR Targetspace for PROGESTERONEZ-score WebGraph NB WebGraph
Targetspace hs 368 222
Targetspace hs pval0.0308641975308640.13863636363636
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:31
Sym Orf Description Function No All Z_score hyperg
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in v... GTPase activating protein (GAP) 21 67 -2.5008 0
DCR2 YLR361C Putative phosphoesterase that functions as a dosage-dependent positive regulator...   20 19   0.0382
SYS1 YJL004C Integral membrane protein of the Golgi required for targeting of the Arf-like GT...   18 41   0
PKR1 YMR123W Protein of unknown function; overproduction confers resistance to Pichia farinos...   18 32   0
VPS17 YOR132W Subunit of the membrane-associated retromer complex essential for endosome-to-Go...   17 21   0
ARL3 YPL051W GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to...   17 42 -4.5744 0
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic; regulates potassiu... ADP-ribosylation factor-like protein 1 17 141   0
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 16 56   0.1051
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   16 30   0
SWF1 YDR126W Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on a...   16 48   0.0039
SKY1 YMR216C SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabo...   16 97   0.0889
Mon2 YNL297C Peripheral membrane protein with a role in endocytosis and vacuole integrity, in...   15 54   NAN
MAK3 YPR051W Catalytic subunit of N-terminal acetyltransferase of the NatC type; required for... N-acetyltransferase 15 20   0
COG6 YNL041C Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   14 57   NAN
TLG2 YOL018C Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fus... tSNARE that affects a late Golgi compartment 14 128   0
MVP1 YMR004W Protein required for sorting proteins to the vacuole; overproduction of Mvp1p su...   14 16   0.0001
VPS29 YHR012W Endosomal protein that is a subunit of the membrane-associated retromer complex ...   14 52   0
TFP1 YDL185W Vacuolar ATPase V1 domain subunit A containing the catalytic nucleotide binding ... protein with three regions (ABC) that are spliced to yield the extein AC and the intein B; AC is a 69K vacuolar (H+)-ATPase, and B is a 50K site-specfic endonuclease named VDE (PI-SceI) that is homologous to HO. Cleavage is meiosis-specific and induces ge|site-specific endonuclease VDE (PI-SceI)|vacuolar ATPase V1 domain subunit A (69 kDa) 14 65 -3.2433 0.047
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   14 12   0
VPS30 YPL120W Protein that forms a membrane-associated complex with Apg14p that is essential f...   13 25   0.0004
CDC50 YCR094W Endosomal protein that regulates cell polarity; similar to Ynr048wp and Lem3p   13 41   NAN
NHX1 YDR456W Endosomal Na+/H+ exchanger, required for intracellular sequestration of Na+; req... Na+/H+ exchanger 13 61   0
RUD3 YOR216C Golgi matrix protein involved in the structural organization of the cis-Golgi; i...   13 100   NAN
VPS21 YOR089C GTPase required for transport during endocytosis and for correct sorting of vacu... small GTP-binding protein 13 42   NAN
IMH1 YLR309C Protein involved in vesicular transport, mediates transport between an endosomal...   13 4   0.0609
CBF1 YJR060W Helix-loop-helix protein that binds the motif CACRTG, which is present at severa... basic helix-loop-helix protein 12 34   0
SNF4 YGL115W Protein kinase activator found in a complex containing Snf1p and members of the ... associates with Snf1p 12 31   0.0001
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in tr... v-SNARE 12 14   0.0216
RER1 YCL001W Protein involved in retention of membrane proteins, including Sec12p, in the ER;...   12 73   0.1292
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex that functions in carboxy...   12 31   0
STV1 YMR054W Subunit of vacuolar-ATPase V0 domain, one of two isoforms (Stv1p and Vph1p); Stv... 110 kDa subunit; not in vacuole membrane|vacuolar H-ATPase 12 10   0

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