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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:38
Sym Orf Description Function No All Z_score hyperg
ARF1 YDL192W ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of... ADP-ribosylation factor 5 126   0
PRE9 YGR135W 20S proteasome beta-type subunit; the only nonessential 20S subunit proteasome component Y13 4 78   0
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleot...   4 66 -0.1832 0
CMP2 YML057W Calcineurin A; one isoform (the other is CNA1) of the catalytic subunit of calci... calcineurin subunit A 4 11   0.0474
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golg... ADP-ribosylation factor GTPase-activating protein (ARF GAP) 3 95   0
GOS1 YHL031C v-SNARE protein involved in Golgi transport, homolog of the mammalian protein GO...   3 56   0
MOT2 YER068W Component of the CCR4-NOT transcription regulatory complex, which represses tran... zinc finger protein (putative) 3 72   0.2197
GET3 YDL100C ATPase, subunit of the GET complex; required for the retrieval of HDEL proteins ...   3 110   0.0001
RPA34 YJL148W RNA polymerase I subunit A34.5   3 41   0
CDC45 YLR103C DNA replication initiation factor; recruited to MCM pre-RC complexes at replicat... chromosomal DNA replication initiation protein 3 108   0.1509
LST8 YNL006W Protein required for the transport of amino acid permease Gap1p from the Golgi t...   2 12   0.0204
  YPL144W     2 15   0.2836
SLX4 YLR135W Subunit of a complex, with Slx1p, that hydrolyzes 5- branches from duplex DNA in...   2 39   0.2861
RPL20B YOR312C Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl2... ribosomal protein L20B (L18B) 2 10   0.0646
QRI8 YMR022W Ubiquitin conjugating enzyme, involved in the ER-associated protein degradation ... ubiquitin-conjugating enzyme 2 69   0.0044
SPC2 YML055W Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyz... signal peptidase complex subunit|similar to mammalian protein SPC25 2 45   0
IGO1 YNL157W Hypothetical protein   2 4   0
SEC21 YNL287W Gamma subunit of coatomer, a heptameric protein complex that together with Arf1p... PEST sequence-containing protein|non-clathrin coat protein 2 26   0.1332
DED1 YOR204W ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase, required for translation ...   2 18   0
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily, required for nonsense mediate... helicase (putative) 2 38   0.0175
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex; deletion phenot...   2 59   0.2236
FET4 YMR319C Low-affinity Fe(II) transporter of the plasma membrane low affinity Fe2+ transport protein 2 7   0.1886
NOT5 YPR072W Subunit of the CCR4-NOT complex, which is a global transcriptional regulator wit... NOT complex member, a global negative regulator of transcription 2 27   0.0046
PMT1 YDL095W Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphat... dolichyl phosphate-D-mannose:protein O-D-mannosyltransferase 2 55   0.1912
MSB1 YOR188W Protein involved in positive regulation of both 1,3-beta-glucan synthesis and th...   2 11   0.1078
IGO2 YHR132W-A Hypothetical protein   2 7   0
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapam... peptidyl-prolyl cis-trans isomerase (PPIase) 2 22   0.0649
WSC3 YOL105C Partially redundant sensor-transducer of the stress-activated PKC1-MPK1 signalin... contains novel cysteine motif|integral membrane protein (putative)|similar to SLG1 (WSC1), WSC2 and WSC4 2 13   0.0013
UTR2 YEL040W Putative glycosidase, glycosylphosphatidylinositol (GPI)-anchored protein locali...   2 8   0.0026
  YGL196W     2 3   0.0013
DOC1 YGL240W Processivity factor required for the ubiquitination activity of the anaphase pro...   2 36 -2.9182 0.1764
CRH1 YGR189C Putative glycosidase of the cell wall, may have a role in cell wall architecture cell wall protein 2 4   0.0002
GNP1 YDR508C High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and As... high affinity glutamine permease 2 33   0.0489
CPR1 YDR155C Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis... cyclophilin|peptidyl-prolyl cis-trans isomerase (PPIase) 2 16   0.0047
UBC4 YBR082C Ubiquitin-conjugating enzyme that mediates degradation of short-lived and abnorm... ubiquitin conjugating enzyme e2 2 45   0.2838
GRS1 YBR121C Cytoplasmic and mitochondrial glycyl-tRNA synthase that ligates glycine to the c... glycine-tRNA ligase 2 6   0.125
FEN1 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis; acts on fatty acids ...   2 21   0.1355
LRG1 YDL240W Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signalin... similar to LIM-domain proteins and to rho/rac GTPase-activating family of proteins 2 19   0.0013

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