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SONAR Targetspace for MECLOFENAMATE SODIUMZ-score WebGraph NB WebGraph
Targetspace hs 126 0
Targetspace hs pval0.0728051391862951
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:33
Sym Orf Description Function No All Z_score hyperg
TLG2 YOL018C Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fus... tSNARE that affects a late Golgi compartment 13 128   0
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in v... GTPase activating protein (GAP) 11 67 -7.5220 0
SYS1 YJL004C Integral membrane protein of the Golgi required for targeting of the Arf-like GT...   10 41   0
VPS17 YOR132W Subunit of the membrane-associated retromer complex essential for endosome-to-Go...   9 21   0.0023
ARL3 YPL051W GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to...   9 42 -10.7788 0
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic; regulates potassiu... ADP-ribosylation factor-like protein 1 9 141   0
MVP1 YMR004W Protein required for sorting proteins to the vacuole; overproduction of Mvp1p su...   8 16   0
SKY1 YMR216C SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabo...   8 97   0.0013
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 8 56   0.0034
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   8 12   0.0002
PKR1 YMR123W Protein of unknown function; overproduction confers resistance to Pichia farinos...   8 32   0
MAK3 YPR051W Catalytic subunit of N-terminal acetyltransferase of the NatC type; required for... N-acetyltransferase 8 20   0
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   8 30   0.0842
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5... function unknown 7 110   0.1327
COG6 YNL041C Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   7 57   NAN
NHX1 YDR456W Endosomal Na+/H+ exchanger, required for intracellular sequestration of Na+; req... Na+/H+ exchanger 7 61   0
INP53 YOR109W Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein w... inositol polyphosphate 5-phosphatase 6 77   0.0027
VPS29 YHR012W Endosomal protein that is a subunit of the membrane-associated retromer complex ...   6 52   0.0222
PEP8 YJL053W Vacuolar protein sorting protein that forms part of the multimeric membrane-asso... vacuolar protein similar to mouse gene H<beta>58 6 27   0
VPS74 YDR372C Non-essential protein of unknown function involved in vacuolar protein sorting; ...   6 47   0.1321
VPS30 YPL120W Protein that forms a membrane-associated complex with Apg14p that is essential f...   6 25   0.145
TFP1 YDL185W Vacuolar ATPase V1 domain subunit A containing the catalytic nucleotide binding ... protein with three regions (ABC) that are spliced to yield the extein AC and the intein B; AC is a 69K vacuolar (H+)-ATPase, and B is a 50K site-specfic endonuclease named VDE (PI-SceI) that is homologous to HO. Cleavage is meiosis-specific and induces ge|site-specific endonuclease VDE (PI-SceI)|vacuolar ATPase V1 domain subunit A (69 kDa) 6 65 -1.9652 0.0687
ERV14 YGL054C Protein localized to COPII-coated vesicles, involved in vesicle formation and in... 14 kDa protein found on ER-derived vesicles 6 76   0
CDC50 YCR094W Endosomal protein that regulates cell polarity; similar to Ynr048wp and Lem3p   6 41   0
RER1 YCL001W Protein involved in retention of membrane proteins, including Sec12p, in the ER;...   6 73   0.0322
TUB2 YFL037W Beta-tubulin; associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin di... beta-tubulin 6 50   0.0123
CBK1 YNL161W Serine/threonine protein kinase that regulates cell morphogenesis pathways; invo... serine/threonine protein kinase 6 41   0.0001
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isome... cyclophilin 40|peptidyl-prolyl cis-trans isomerase (PPIase) 5 33   0.1741
GOS1 YHL031C v-SNARE protein involved in Golgi transport, homolog of the mammalian protein GO...   5 56   0
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   5 23   0
COG8 YML071C Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   5 56   0
PIK1 YNL267W Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosp... phosphatidylinositol 4-kinase 5 108   0.0004
SWA2 YDR320C Auxilin-like protein involved in vesicular transport; clathrin-binding protein r... auxilin-like protein 5 24   0

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