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SONAR Targetspace for IBUPROFENZ-score WebGraph NB WebGraph
Targetspace hs 135 0
Targetspace hs pval0.357723577235771
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
FUS3 YBL016W Mitogen-activated protein kinase involved in mating pheromone response; activate... CDC28/cdc2 related protein kinase 10 32   0
SEC12 YNR026C Guanine nucleotide exchange factor (GEF); glycosylated integral membrane protein... guanine nucleotide exchange factor for Sar1p 8 27   0
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding and autopha... vesicle coat component 8 14   0
SEC13 YLR208W Component of both the Nup84 nuclear pore sub-complex and of the COPII complex (S... nuclear pore complex subunit|protein involved in release of transport vesicles from the ER 8 25   0
SEC23 YPR181C GTPase-activating protein; component of the Sec23p-Sec24p heterodimeric complex ... GTPase activating protein (GAP) 8 30   0
STE11 YLR362W Signal transducing MEK kinase involved in pheromone response and pseudohyphal/in...   7 70   0
GIC2 YDR309C Protein of unknown function involved in initiation of budding and cellular polar...   6 36   0.0008
BCK2 YER167W Protein rich in serine and threonine residues involved in protein kinase C signa...   6 47 -0.6295 0
SGD1 YLR336C Essential nuclear protein with a possible role in the osmoregulatory glycerol re...   6 4   0
MSB2 YGR014W Mucin family member at the head of the Cdc42p- and MAP kinase-dependent filament... integral membrane protein (putative) 6 20   0
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways... MAP kinase 6 26   0
GTR2 YGR163W Cytoplasmic GTP binding protein, negative regulator of the Ran/Tc4 GTPase cycle ... similar to Gtr1|small GTPase (putative) 6 16   0
SEC6 YIL068C Essential 88kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec1... exocyst complex component 6 43   0.1635
QRI8 YMR022W Ubiquitin conjugating enzyme, involved in the ER-associated protein degradation ... ubiquitin-conjugating enzyme 5 69   0.0651
STE4 YOR212W G protein beta subunit, forms a dimer with Ste18p to activate the mating signali... G protein beta subunit|coupled to mating factor receptor 5 42   0
SDA1 YGR245C Highly conserved nuclear protein required for actin cytoskeleton organization an...   5 2   0
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide ... Hsp70 family 5 80   0.1056
SLM4 YBR077C Component of the EGO complex, which is involved in the regulation of microautoph...   5 10   0
RGA2 YDR379W GTPase-activating protein for the polarity-establishment protein Cdc42p; implica... Rho-GTPase Activating Protein 5 8   0
HEM1 YDR232W 5-aminolevulinate synthase, catalyzes the first step in the heme biosynthetic pa... 5-aminolevulinate synthase 5 10   0
HRT1 YOL133W RING finger containing subunit of Skp1-Cullin-F-box ubiquitin protein ligases (S... Skp1-Cullin-F-box ubiquitin protein ligase (SCF) subunit 4 13   0
SEC17 YBL050W Peripheral membrane protein required for vesicular transport between ER and Golg...   4 11   0
FAR1 YJL157C Cyclin-dependent kinase inhibitor that mediates cell cycle arrest in response to... Cdc28p kinase inhibitor 4 24   0
MLF3 YNL074C Serine-rich protein of unknown function; overproduction suppresses the growth in...   4 9   0
CDC33 YOL139C Cytoplasmic mRNA cap binding protein; the eIF4E-cap complex is responsible for m... mRNA cap binding protein eIF-4E 4 19   0.0105
FAR3 YMR052W Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway ...   4 7   0
ERD2 YBL040C Integral membrane protein that binds to the HDEL motif in proteins destined for ... HDEL receptor 4 8   0.0067
SEC31 YDL195W Essential phosphoprotein component (p150) of the COPII coat of secretory pathway... COPII coat of secretory pathway vesicles component (p150) 4 9   0
UFE1 YOR075W t-SNARE required for ER membrane fusion and vesicular traffic, integral membrane... t-SNARE (ER) 4 18   0.0007
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p), a complex that regulates g...   4 16   0.0493
VHS2 YIL135C Cytoplasmic protein of unknown function; identified as a high-copy suppressor of...   4 15   0
GCN4 YEL009C Transcriptional activator of amino acid biosynthetic genes in response to amino ... transcriptional activator of amino acid biosynthetic genes 4 40   0
DER1 YBR201W Endoplasmic reticulum membrane protein, required for ER-associated protein degra...   4 20   0.1431
  YBR138C     4 1   0
  YKL206C     4 3   0
BOP3 YNL042W Protein of unknown function, potential Cdc28p substrate; overproduction suppress...   4 2   0
GPA1 YHR005C GTP-binding alpha subunit of the heterotrimeric G protein that couples to pherom... G protein alpha subunit|coupled to mating factor receptor 4 24   0
BNA4 YBL098W Kynurenine 3-mono oxygenase, required for biosynthesis of nicotinic acid from tr... Kynurenine 3-mono oxygenase 4 8   0
MRS5 YBR091C Essential protein of the inner mitochondrial membrane, peripherally localized; c...   4 6   0
NGR1 YBR212W RNA binding protein that negatively regulates growth rate; interacts with the 3-... glucose-repressible RNA binding protein 4 4   0

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