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SONAR Targetspace for IBUPROFENZ-score WebGraph NB WebGraph
Targetspace hs 135 0
Targetspace hs pval0.357723577235771
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
SIC1 YLR079W Inhibitor of Cdc28-Clb kinase complexes that controls G1/S phase transition, pre...   12 45   0.0081
PTC2 YER089C Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress ... protein phosphatase type 2C 11 15   0
ADA2 YDR448W Transcription coactivator, component of the ADA and SAGA transcriptional adaptor... transcription factor 9 108   0
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex, a histone... Ada/Gcn5 protein complex member|transcription factor 9 49   0
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton o... rho GTPase activating protein (GAP) 9 21   0
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex, involved in maintaining ... histone acetyltransferase SAGA complex member|transcription factor 9 52   0
IRE1 YHR079C Serine-threonine kinase and endoribonuclease; transmembrane protein that initiat... endoribonuclease|serine-threonine kinase|transmembrane protein 8 95 -7.3277 0.111
GRR1 YJR090C F-box protein component of the SCF ubiquitin-ligase complex, required for Cln1p ...   8 42   0.0955
MLF3 YNL074C Serine-rich protein of unknown function; overproduction suppresses the growth in...   8 16   0
GCN5 YGR252W Histone acetyltransferase, acetylates lysine 14 on histone H3; catalytic subunit... histone acetyltransferase 7 119 -1.9506 0.1559
RGA1 YOR127W GTPase-activating protein for the polarity-establishment protein Cdc42p; implica... rho GTPase activating protein (GAP) 7 24   0
RET1 YOR207C Second-largest subunit of RNA polymerase III, which is responsible for the trans...   7 52   0.0656
CDC48 YDL126C ATPase in ER, nuclear membrane and cytosol with homology to mammalian p97; in a ...   7 104   0
TOK1 YJL093C Outward-rectifier potassium channel of the plasma membrane with two pore domains... outward-rectifier potassium channel 6 3   0.0006
KAR2 YJL034W ATPase involved in protein import into the ER, also acts as a chaperone to media... HSP70 family|mammalian BiP (GRP78 or HSPA5) homolog 6 58   0
NHA1 YLR138W Na+/H+ antiporter involved in sodium and potassium efflux through the plasma mem...   6 8   0
PTP2 YOR208W Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 6 13   0
RCK2 YLR248W Protein kinase involved in the response to oxidative and osmotic stress; identif...   6 48   0
  YLR257W     6 18   0
NPR1 YNL183C Protein kinase that stabilizes several plasma membrane amino acid transporters b... protein kinase homolog 6 39 -12.2832 0
SMP1 YBR182C Putative transcription factor involved in regulating the response to osmotic str...   6 11   0
ATG19 YOL082W Protein involved in the cytoplasm-to-vacuole targeting pathway and in autophagy,... Receptor for biosynthetic cytoplasm to vacuole targeting 6 40   0
SKO1 YNL167C Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family that for...   6 16   0
FPS1 YLL043W Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) fa... glycerol channel protein 6 13   0
FAR1 YJL157C Cyclin-dependent kinase inhibitor that mediates cell cycle arrest in response to... Cdc28p kinase inhibitor 6 37   0
LST8 YNL006W Protein required for the transport of amino acid permease Gap1p from the Golgi t...   6 38   0
STE20 YHL007C Signal transducing kinase of the PAK (p21-activated kinase) family, involved in ...   6 117   0
TPO3 YPR156C Polyamine transport protein specific for spermine; localizes to the plasma membr...   6 5   0
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   6 34   0
SCH9 YHR205W Protein kinase that regulates signal transduction activity and G1 progression, c... cAMP-dependent protein kinase homolog|suppressor of cdc25ts 5 25   0
ISA2 YPR067W Protein required for maturation of mitochondrial and cytosolic Fe/S proteins, lo...   5 15   0.0007
SAS10 YDL153C Component of the small (ribosomal) subunit (SSU) processosome required for pre-1... U3 snoRNP protein 5 51   0
RTG3 YBL103C Basic helix-loop-helix-leucine zipper (bHLH/Zip) transcription factor that forms... phosphoprotein 5 24   0
CRM1 YGR218W Major karyopherin, involved in export of proteins, RNAs, and ribosomal subunits ... chromosome region maintenance protein 5 111   0
  YML045W-A     4 16   0
  YMR046C     4 7   0
SIP5 YMR140W Protein of unknown function; interacts with both the Reg1p/Glc7p phosphatase and...   4 30   0
  YMR184W     4 19   0
  YLR410W-A     4 7   0
  YPR091C     4 17   0

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