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SONAR Targetspace for IBUPROFENZ-score WebGraph NB WebGraph
Targetspace hs 135 0
Targetspace hs pval0.357723577235771
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:38
Sym Orf Description Function No All Z_score hyperg
ERG1 YGR175C Squalene epoxidase, catalyzes the epoxidation of squalene to 2,3-oxidosqualene; ... squalene monooxygenase 12 36   0
MLF3 YNL074C Serine-rich protein of unknown function; overproduction suppresses the growth in...   12 26   0
SSP120 YLR250W Protein of unknown function; green fluorescent protein (GFP)-fusion protein loca...   8 11   0
  YHR045W     8 22   0
ERP5 YHR110W Protein with similarity to Emp24p and Erv25p, member of the p24 family involved ... p24 protein involved in membrane trafficking 8 45   0
SPC2 YML055W Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyz... signal peptidase complex subunit|similar to mammalian protein SPC25 8 99   0.0129
  YLR064W     8 34   0
GPI17 YDR434W Transmembrane protein subunit of the glycosylphosphatidylinositol transamidase c... GPI transamidase component, human PIG-S homologue 8 24   0.0072
YSY6 YBR162W-A Protein whose expression suppresses a secretory pathway mutation in E. coli; has...   7 29   0
VHS2 YIL135C Cytoplasmic protein of unknown function; identified as a high-copy suppressor of...   7 43   0
SEC23 YPR181C GTPase-activating protein; component of the Sec23p-Sec24p heterodimeric complex ... GTPase activating protein (GAP) 7 82   0
  YBR238C     7 123   0
  YBR138C     7 10   0
ATG19 YOL082W Protein involved in the cytoplasm-to-vacuole targeting pathway and in autophagy,... Receptor for biosynthetic cytoplasm to vacuole targeting 6 44   0
SEC6 YIL068C Essential 88kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec1... exocyst complex component 6 58   0.1635
MSN4 YKL062W Transcriptional activator related to Msn2p; activated in stress conditions, whic... zinc finger protein 6 64   0
RCK2 YLR248W Protein kinase involved in the response to oxidative and osmotic stress; identif...   6 68   0
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex, involved in maintaining ... histone acetyltransferase SAGA complex member|transcription factor 6 89   0
SKO1 YNL167C Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family that for...   6 38   0
STE11 YLR362W Signal transducing MEK kinase involved in pheromone response and pseudohyphal/in...   6 114   0
GIC2 YDR309C Protein of unknown function involved in initiation of budding and cellular polar...   6 76   0.0008
MSB2 YGR014W Mucin family member at the head of the Cdc42p- and MAP kinase-dependent filament... integral membrane protein (putative) 6 46   0
GTR2 YGR163W Cytoplasmic GTP binding protein, negative regulator of the Ran/Tc4 GTPase cycle ... similar to Gtr1|small GTPase (putative) 6 37   0
TOK1 YJL093C Outward-rectifier potassium channel of the plasma membrane with two pore domains... outward-rectifier potassium channel 6 25   0.0006
ATF2 YGR177C Alcohol acetyltransferase, may play a role in steroid detoxification; forms vola... alcohol acetyltransferase 6 29   0.0037
STE4 YOR212W G protein beta subunit, forms a dimer with Ste18p to activate the mating signali... G protein beta subunit|coupled to mating factor receptor 5 69   0
ISA2 YPR067W Protein required for maturation of mitochondrial and cytosolic Fe/S proteins, lo...   5 18   0.0007
RGA2 YDR379W GTPase-activating protein for the polarity-establishment protein Cdc42p; implica... Rho-GTPase Activating Protein 5 43   0
  YLR257W     5 20   0
SEC12 YNR026C Guanine nucleotide exchange factor (GEF); glycosylated integral membrane protein... guanine nucleotide exchange factor for Sar1p 5 51   0.0017
BUD2 YKL092C GTPase activating factor for Rsr1p/Bud1p required for both axial and bipolar bud... GTPase activating protein (GAP) for Rsr1p/Bud1p 5 19   0
NPR1 YNL183C Protein kinase that stabilizes several plasma membrane amino acid transporters b... protein kinase homolog 5 59 -12.2832 0
ATG11 YPR049C Peripheral membrane protein required for delivery of aminopeptidase I (Lap4p) to... Oligomeric, coiled-coil, peripheral membrane protein required for stable binding of precursor API to its target membrane. 5 76   0
HEM1 YDR232W 5-aminolevulinate synthase, catalyzes the first step in the heme biosynthetic pa... 5-aminolevulinate synthase 5 13   0
NHA1 YLR138W Na+/H+ antiporter involved in sodium and potassium efflux through the plasma mem...   5 26   0
SAS10 YDL153C Component of the small (ribosomal) subunit (SSU) processosome required for pre-1... U3 snoRNP protein 5 56   0
GCN4 YEL009C Transcriptional activator of amino acid biosynthetic genes in response to amino ... transcriptional activator of amino acid biosynthetic genes 5 94   0
PTP2 YOR208W Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 5 51   0.0001

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