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SONAR Targetspace for ETHOPROPAZINE HYDROCHLORIDEZ-score WebGraph NB WebGraph
Targetspace hs 84 0
Targetspace hs pval0.3361
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:38
Sym Orf Description Function No All Z_score hyperg
BUD14 YAR014C Protein involved in bud-site selection, Bud14p-Glc7p complex functions as a cort...   5 74   0.0001
VMA6 YLR447C Subunit D of the five-subunit V0 integral membrane domain of vacuolar H+-ATPase ... vacuolar ATPase V0 domain subunit d (36 kDa)|vacuolar H(+) ATPase 36 kDa subunit (D subunit of VO sector) 4 32   0.0046
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex, which is involved in regulati...   3 57 -25.6121 0
TKL1 YPR074C Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate an... transketolase 1 3 18   0.0504
PRK1 YIL095W Protein serine/threonine kinase; regulates the organization and function of the ... serine/threonine protein kinase 3 94   0.0257
TIF3 YPR163C Translation initiation factor eIF-4B, has RNA annealing activity; contains an RN... translation initiation factor eIF-4B 3 17 -2.4187 0
  YOL087C     3 21   0
STE24 YJR117W Highly conserved zinc metalloprotease that functions in two steps of a-factor ma... zinc metallo-protease 3 7   0.0796
SSN8 YNL025C Cyclin-like component of the RNA polymerase II holoenzyme, involved in phosphory... C-type cyclin|associates with the Ssn3p cyclin-dependent kinase 3 50   0.0025
VMA13 YPR036W Subunit H of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-... vacuolar H(+) ATPase V1 sector 54 kDa subunit 3 28   0.164
FAS2 YPL231W Alpha subunit of fatty acid synthetase, which catalyzes the synthesis of long-ch... fatty acid synthase alpha subunit 3 27   0
YDJ1 YNL064C Protein chaperone involved in regulation of the HSP90 and HSP70 functions; invol... heat shock protein|yeast dnaJ homolog (nuclear envelope protein) 3 56   0.0026
YSH1 YLR277C Putative endonuclease, subunit of the mRNA cleavage and polyadenylation specific... cleavage factor II (CF II) component|polyadenylation factor I (PF I) 3 42   0
SEM1 YDR363W-A Component of the lid subcomplex of the regulatory subunit of the 26S proteasome;...   3 58   0
RBG1 YAL036C Member of the DRG family of GTP-binding proteins; interacts with translating rib...   3 24   0
CBR1 YIL043C Microsomal cytochrome b reductase, not essential for viability; also detected in... cytochrome b reductase 3 27   0.1524
RHO1 YPR165W GTP-binding protein of the rho subfamily of Ras-like proteins, involved in estab... GTP-binding protein|rho subfamily 3 47   0.0398
VPH1 YOR270C Subunit of vacuolar-ATPase V0 domain, one of two isoforms (Vph1p and Stv1p); Vph... V0 sector subunit|essential for vacuolar acidification and vacuolar H-ATPase activity|vacuolar ATPase V0 domain subunit a (100 kDa)|vacuolar H-ATPase 3 43 -5.9663 0.1963
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family involved in mRNA e... RNA helicase 3 24   0
FLC2 YAL053W Putative protein of unknown function; green fluorescent protein (GFP)-fusion pro...   3 7   0.0315
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p, involved in negative reg... Glc7p regulatory subunit 3 34   0.1046
RPP0 YLR340W Conserved ribosomal protein P0 similar to rat P0, human P0, and E. coli L10e; sh... ribosomal protein P0 (A0) (L10E) 3 124   0
FIN1 YDR130C Spindle pole body-related intermediate filament protein, forms cell cycle-specif...   3 96   0
RPL24A YGL031C Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to ... ribosomal protein L24A (rp29) (YL21) (L30A) 2 68   0.0668
UFD4 YKL010C Ubiquitin-protein ligase (E3) that interacts with Rpt4p and Rpt6p, two subunits ... ubiquitin ligase e3 2 33   0.0201
SCD6 YPR129W Protein containing an Lsm domain, may bind RNA and have a role in RNA processing...   2 43   0.0138
RPL28 YGL103W Ribosomal protein L29 of the large (60S) ribosomal subunit, has similarity to E.... ribosomal protein L28 (L29) (rp44) (YL24) 2 113   0
CDC42 YLR229C Small rho-like GTPase, essential for establishment and maintenance of cell polar... Rho subfamily of Ras-like proteins 2 46   0.0007
RPN7 YPR108W Essential, non-ATPase regulatory subunit of the 26S proteasome, similar to anoth... proteasome regulatory particle subunit 2 59   0
MSN5 YDR335W Karyopherin involved in nuclear import and export; shown to be responsible for n...   2 57 -1.9699 0.1528
ERP2 YAL007C Protein that forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; memb... p24 protein involved in membrane trafficking 2 32   0
LCB2 YDR062W Component of serine palmitoyltransferase, responsible along with Lcb1p for the f... serine palmitoyltransferase component 2 22   0.087
  YGL059W     2 94   0
PTP1 YDL230W Phosphotyrosine-specific protein phosphatase that dephosphorylates a broad range... phosphotyrosine-specific protein phosphatase 2 12   0
TRS20 YBR254C One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-...   2 23   0
  YAR009C     2 9   0
FUS3 YBL016W Mitogen-activated protein kinase involved in mating pheromone response; activate... CDC28/cdc2 related protein kinase 2 129   0.0063
FTH1 YBR207W Putative high affinity iron transporter involved in transport of intravacuolar s...   2 10   0

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