Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for ETHOPROPAZINE HYDROCHLORIDEZ-score WebGraph NB WebGraph
Targetspace hs 84 0
Targetspace hs pval0.3361
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
CLN3 YAL040C G1 cyclin involved in cell cycle progression; activates Cdc28p kinase to promote... G1 cyclin 4 71   0.0101
CMP2 YML057W Calcineurin A; one isoform (the other is CNA1) of the catalytic subunit of calci... calcineurin subunit A 4 11   0.0474
PXL1 YKR090W LIM domain-containing protein that localizes to sites of polarized growth, requi...   4 4   0.0048
RPL20B YOR312C Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl2... ribosomal protein L20B (L18B) 4 10   0.0009
HBT1 YDL223C Substrate of the Hub1p ubiquitin-like protein that localizes to the shmoo tip (m...   3 6   0.1444
SWE1 YJL187C Protein kinase that regulates the G2/M transition by inhibition of Cdc28p kinase... tyrosine kinase 3 59 -3.0369 0.0734
DOC1 YGL240W Processivity factor required for the ubiquitination activity of the anaphase pro...   3 36 -7.0820 0.0526
SLA1 YBL007C Cytoskeletal protein binding protein required for assembly of the cortical actin... cytoskeletal protein binding protein 3 52   0.0006
RPA34 YJL148W RNA polymerase I subunit A34.5   3 41   0
MSB1 YOR188W Protein involved in positive regulation of both 1,3-beta-glucan synthesis and th...   3 11   0.0221
RPA49 YNL248C RNA polymerase I subunit A49 RNA polymerase A 49 kDa alpha subunit 3 44 -1.6396 0.2124
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit; nearly identical to Rps2... ribosomal protein S21B (S26B) (YS25) 2 10   0.2678
IMP2- YIL154C Transcriptional activator involved in maintenance of ion homeostasis and protect... transcription factor 2 13   0.0003
MTR2 YKL186C mRNA transport regulator, essential nuclear protein; Mex67p and Mtr2p form a mRN... mRNA transport regulator 2 12   0.0344
  YJL046W     2 7   0.0034
CRH1 YGR189C Putative glycosidase of the cell wall, may have a role in cell wall architecture cell wall protein 2 4   0.0002
KAP120 YPL125W Karyopherin with a role in the assembly or export of 60S ribosomal subunits karyopherin 2 17   0.0014
CPR1 YDR155C Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis... cyclophilin|peptidyl-prolyl cis-trans isomerase (PPIase) 2 16   0.0047
  YGL081W     2 9   0.0119
  YGL196W     2 3   0.0013
TDP1 YBR223C Tyrosyl-DNA Phosphodiesterase I, hydrolyzes 3--phosphotyrosyl bonds to generate ...   2 29   0.0284
NUC1 YJL208C Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activit... nuclease 2 4   0.0862
DFG16 YOR030W Probable multiple transmembrane protein, involved in invasive growth upon nitrog...   2 21   0.0005
FKS3 YMR306W Protein of unknown function, has similarity to 1,3-beta-D-glucan synthase cataly...   2 3   0.0054
PFA4 YOL003C Palmitoyltransferase with autoacylation activity; member of a family of putative... palmitoyltransferase 2 7   0.2632
APL2 YKL135C Beta-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; b... beta-adaptin|clathrin associated protein complex large subunit 2 19   0
WSC3 YOL105C Partially redundant sensor-transducer of the stress-activated PKC1-MPK1 signalin... contains novel cysteine motif|integral membrane protein (putative)|similar to SLG1 (WSC1), WSC2 and WSC4 2 13   0.0013
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs; high-copy suppressor of g...   2 13   0.0016
QRI5 YLR204W Mitochondrial protein of unknown function   2 10   0.1144
HIT1 YJR055W Protein of unknown function, required for growth at high temperature   2 11   0.2831
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal... RNA helicase (putative) 2 10   0.0132
RRP6 YOR001W Exonuclease component of the nuclear exosome; contributes to the quality-control...   2 61 -1.0967 0.1552
  YLR021W     2 15   0.0711
LRG1 YDL240W Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signalin... similar to LIM-domain proteins and to rho/rac GTPase-activating family of proteins 2 19   0.0013
CWH43 YCR017C Putative sensor/transporter protein involved in cell wall biogenesis; contains 1...   2 48   0.0036
FEN1 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis; acts on fatty acids ...   2 21   0.1355
GIC1 YHR061C Protein of unknown function involved in initiation of budding and cellular polar...   2 37   0.2833
RDH54 YBR073W DNA-dependent ATPase, stimulates strand exchange by modifying the topology of do... helicase (putative)|similar to RAD54 2 19   0.2197
CDC39 YCR093W Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA l... transcriptional regulator 2 23   0.0018
RPO21 YDL140C RNA polymerase II largest subunit B220, part of central core; phosphorylation of... RNA polymerase II core subunit 2 63   0.0005

Service provided by the Mike Tyers Laboratory