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SONAR Targetspace for EQUILINZ-score WebGraph NB WebGraph
Targetspace hs 136 94
Targetspace hs pval0.0459290187891440.24937655860349
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:39
Sym Orf Description Function No All Z_score hyperg
MDR1 YGR100W Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p, Ypt31... GTPase activating protein (GAP) for Ypt6 14 13   0
GDI1 YER136W GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by r... GDP dissociation inhibitor 14 25   0
GYP6 YJL044C GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved... GTPase activating protein (GAP) for Ypt6 14 13   0
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleot...   14 10 -10.0703 0
YIP3 YNL044W Protein localized to COPII vesicles, proposed to be involved in ER to Golgi tran...   14 43   NAN
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network; forms heterod...   9 14 -7.8313 0
ACO1 YLR304C Aconitase, required for the tricarboxylic acid (TCA) cycle and also independentl... aconitase 7 28   0
SGM1 YJR134C Protein of unknown function, required for wild-type growth rate on galactose and...   7 8   0.0082
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5...   7 12   0
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5... hydrophilic protein that is peripherally associated with the late Golgi and forms a stable complex with Vps52p and Vps54p 7 18   0.0001
YIP1 YGR172C Integral membrane protein required for the biogenesis of ER-derived COPII transp...   7 28   0.0001
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   7 45   NAN
YIP4 YGL198W Protein that interacts with Rab GTPases; computational analysis of large-scale p...   7 26   0
YOP1 YPR028W Membrane protein that interacts with Yip1p to mediate membrane traffic; overexpr...   7 17   0
VAM6 YDL077C Vacuolar protein that plays a critical role in the tethering steps of vacuolar m...   7 39   0.0834
VPS33 YLR396C ATP-binding protein that is a subunit of the homotypic vacuole fusion and vacuol...   7 35   0
MRS6 YOR370C Rab escort protein, forms a complex with the Ras-like small GTPase Ypt1p that is... rab geranylgeranyltransferase regulatory subunit 7 22   0
MSB4 YOL112W GTPase-activating protein of the Ras superfamily that acts primarily on Sec4p, l...   7 11   0
YIF1 YNL263C Integral membrane protein required for the fusion of ER-derived COPII transport ...   7 39   0
VPS54 YDR027C Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5...   6 22   0
ZUO1 YGR285C Cytosolic ribosome-associated chaperone that acts, together with Ssz1p and the S... zuotin, Z-DNA binding protein (putative) 6 50   0
COG6 YNL041C Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   6 31   0
YEF3 YLR249W Translational elongation factor, stimulates the binding of aminoacyl-tRNA (AA-tR... Translation elongation factor 3 (EF-3) 5 94   0
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p, involved in nuclear transport GTPase activating protein (GAP) for Gsp1p 5 27   0
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family, redundant in function and nearly iden... chaperonin 4 144   0.1769
RIX7 YLL034C Putative ATPase of the AAA family, required for export of pre-ribosomal large su...   4 60   0
SYG1 YIL047C Plasma membrane protein of unknown function; truncation and overexpression suppr... plasma membrane protein 3 5   0
LSM2 YBL026W Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either L... snRNA-associated protein, Sm class 3 101   0
YPT6 YLR262C GTPase, Ras-like GTP binding protein involved in the secretory pathway, required... similar to the human GTPase, Rab6 3 35 -9.7101 0
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases with similarity to ...   2 57   0
CBF2 YGR140W Essential kinetochore protein, component of the CBF3 multisubunit complex that b... centromere binding factor CBF3 110 kDa subunit 2 39   0.2006
MPS1 YDL028C Dual-specificity kinase required for spindle pole body (SPB) duplication and spi...   2 70   0.2734
RGA2 YDR379W GTPase-activating protein for the polarity-establishment protein Cdc42p; implica... Rho-GTPase Activating Protein 2 25   0.0285
PBS2 YJL128C MAP kinase kinase that plays a pivotal role in the osmosensing signal-transducti... MAP kinase kinase (MEK)|may act as a scaffolding protein for Sho1p, Ste11p, and Hog1p 2 38   0
MSB3 YNL293W GTPase-activating protein for Sec4p and several other Rab GTPases, regulates exo... GTPase activating protein (GAP) for Ypt6 2 27   0
TRX2 YGR209C Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells... EC 1.8.4.8|thioredoxin 2 24   0
TPN1 YGL186C Plasma membrane pyridoxine (vitamin B6) transporter; member of the purine-cytosi... plasma membrane pyridoxine transport protein 1 1   0
PCL10 YGL134W Pho85p cyclin; recruits, activates, and targets Pho85p cyclin-dependent protein ...   1 25   0
MDS3 YGL197W Protein with an N-terminal kelch-like domain, putative negative regulator of ear...   1 21   0.0484

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