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SONAR Targetspace for DICLOFENAC SODIUMZ-score WebGraph NB WebGraph
Targetspace hs 305 86
Targetspace hs pval0.167832167832170.34677419354839
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   6 12   0.0049
DCR2 YLR361C Putative phosphoesterase that functions as a dosage-dependent positive regulator...   5 19   0
RPL35A YDL191W Protein component of the large (60S) ribosomal subunit, identical to Rpl35Bp and... ribosomal protein L35A 4 13   0.1574
GUT2 YIL155C Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by bot... glycerol-3-phosphate dehydrogenase 4 10   0
SEC28 YIL076W Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein tr... epsilon-COP coatomer subunit 3 19   0
  YIL039W     3 65   0
INP51 YIL002C Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein w... phosphatidylinositol 4,5-bisphosphate 5-phosphatase 3 24   0.0002
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   3 30   0.1228
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway, along with Nam7p an...   3 20   0.034
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline... clathrin assembly complex beta adaptin component (putative) 3 10   0
GEF1 YJR040W Chloride channel localized to late- or post-Golgi vesicles, involved in iron met... transport protein involved in intracellular iron metabolism (putative) 3 10   0
ZRT1 YGL255W High-affinity zinc transporter of the plasma membrane, responsible for the major...   3 7   0.232
EMP70 YLR083C Protein whose 24kDa cleavage product is found in endosome-enriched membrane frac...   3 7   0.2319
MVP1 YMR004W Protein required for sorting proteins to the vacuole; overproduction of Mvp1p su...   3 16   0
ENT4 YLL038C Protein of unknown function, contains an N-terminal epsin-like domain   3 4   0.208
GMH1 YKR030W Golgi membrane protein of unknown function, interacts with Gea1p and Gea2p; requ...   3 5   0.0261
TEF4 YKL081W Translation elongation factor EF-1 gamma translation elongation factor EF-1gamma 3 15   0.223
IRS4 YKR019C Protein involved in regulation of phosphatidylinositol 4,5-bisphosphate concentr...   3 10   0.2222
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 3 56   0
  YMR010W     3 4   0
SRO9 YCL037C Cytoplasmic RNA-binding protein that associates with translating ribosomes; invo...   3 30   0.0065
MAK31 YCR020C-A Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; required...   3 5   0
RER1 YCL001W Protein involved in retention of membrane proteins, including Sec12p, in the ER;...   3 73   0.0019
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3); functions in... clathrin associated protein complex medium subunit 3 15   0
HST1 YOL068C NAD(+)-dependent histone deacetylase; essential subunit of the Sum1p/Rfm1p/Hst1p...   3 25   0
SFT2 YBL102W Non-essential tetra-spanning membrane protein found mostly in the late Golgi, ca...   3 8   0
SEC18 YBR080C ATPase required for the release of Sec17p during the -priming- step in homotypic... ATPase|NSF|protein involved in protein transport between ER and Golgi 3 33   0.2144
MAF1 YDR005C Negative regulator of RNA polymerase III; component of several signaling pathway...   3 50   0.064
VPS41 YDR080W Vacuolar membrane protein that is a subunit of the homotypic vacuole fusion and ...   3 14   0.2218
  YEL043W     3 4   0
SBH1 YER087C-B Beta subunit of the Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p); involv... Sbh2p homolog 3 11   0
SEC20 YDR498C Membrane glycoprotein v-SNARE involved in retrograde transport from the Golgi to... v-SNARE 3 9   0.1012
TLG1 YDR468C Essential t-SNARE that forms a complex with Tlg2p and Vti1p and mediates fusion ... tSNARE that affects a late Golgi compartment 3 6   0.0049
  YDR107C     3 5   0.0447
ENT5 YDR153C Protein containing an N-terminal epsin-like domain involved in clathrin recruitm...   3 8   0.1301
  YDR266C     3 6   0
BST1 YFL025C GPI inositol deacylase of the ER that negatively regulates COPII vesicle formati...   3 41   0
RET1 YOR207C Second-largest subunit of RNA polymerase III, which is responsible for the trans...   3 6   0.2021
DSS4 YPR017C Nucleotide release factor functioning in the post-Golgi secretory pathway, requi... GDP dissociation factor for Sec4p 3 14   0.0751
NTO1 YPR031W Component of the histone acetyltransferase complex HAT complex component 3 10   0.0001

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