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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:37
Sym Orf Description Function No All Z_score hyperg
SLX8 YER116C Protein containing a RING finger domain that forms a complex with Hex3p; mutant ...   4 121   0
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex; deletion phenot...   3 59   0.2392
MUS81 YDR386W Helix-hairpin-helix protein, involved in DNA repair and replication fork stabili...   3 72   0
SAE2 YGL175C Protein with a role in accurate meiotic and mitotic double-strand break repair; ...   2 33   0.28
  YLL033W     2 19   0.0705
ERG2 YMR202W C-8 sterol isomerase, catalyzes the isomerization of the delta-8 double bond to ... C-8 sterol isomerase 2 109   0
SAP155 YFR040W Protein that forms a complex with the Sit4p protein phosphatase and is required ...   2 29   0
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor (GEF or GDP-release factor); i... adenylate cyclase regulatory protein 2 36   0.277
CDC2 YDL102W Catalytic subunit of DNA polymerase delta; required for chromosomal DNA replicat... DNA polymerase III catalytic (delta) subunit 2 90   0.0028
CDC6 YJL194W Essential ATP-binding protein required for DNA replication, component of the pre... pre-initiation complex component 2 64   0
ORC6 YHR118C Subunit of the origin recognition complex, which directs DNA replication by bind... ORC 50 kDa subunit 2 34   0.0108
CKB1 YGL019W Beta regulatory subunit of casein kinase 2, a Ser/Thr protein kinase with roles ... protein kinase CK2 beta subunit 2 28   0.2683
PXL1 YKR090W LIM domain-containing protein that localizes to sites of polarized growth, requi...   2 4   0.1236
UPC2 YDR213W Sterol regulatory element binding protein, induces transcription of sterol trans... zinc finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type 2 24   0
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton o... rho GTPase activating protein (GAP) 2 22   0.2351
MSB1 YOR188W Protein involved in positive regulation of both 1,3-beta-glucan synthesis and th...   2 11   0.1078
RHO2 YNL090W Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, involv... GTP-binding protein|rho subfamily 2 26   0.1895
HYM1 YKL189W Component of the RAM signaling network that is involved in regulation of Ace2p a...   2 24   0.0904
CBK1 YNL161W Serine/threonine protein kinase that regulates cell morphogenesis pathways; invo... serine/threonine protein kinase 2 41   0.1429
MOT2 YER068W Component of the CCR4-NOT transcription regulatory complex, which represses tran... zinc finger protein (putative) 2 72   0.1703
NHX1 YDR456W Endosomal Na+/H+ exchanger, required for intracellular sequestration of Na+; req... Na+/H+ exchanger 2 61   0.0793
DHH1 YDL160C Cytoplasmic DExD/H-box helicase, stimulates mRNA decapping, coordinates distinct...   2 46   0.0456
MMS4 YBR098W Subunit of the structure-specific Mms4p-Mus81p endonuclease that cleaves branche...   2 54   0
NOT5 YPR072W Subunit of the CCR4-NOT complex, which is a global transcriptional regulator wit... NOT complex member, a global negative regulator of transcription 2 27   0.0046
TOK1 YJL093C Outward-rectifier potassium channel of the plasma membrane with two pore domains... outward-rectifier potassium channel 2 7   0.2053
TRK2 YKR050W Component of the Trk1p-Trk2p potassium transport system low affinity potassium transport|membrane protein 2 21   0.0208
RRN3 YKL125W Protein required for transcription of rDNA by RNA polymerase I; transcription fa... DNA independent RNA polymerase I transcription factor 2 6   0.0831
RPA135 YPR010C RNA polymerase I subunit A135 RNA polymerase I subunit 2 6   0.0831
RTT107 YHR154W Protein that interacts with Mms22p and is implicated in Mms22-dependent DNA repa...   1 94   0
THP2 YHR167W Subunit of the THO complex, which connects transcription elongation and mitotic ...   1 23   0.1013
PTH1 YHR189W One of two (see also PTH2) mitochondrially-localized peptidyl-tRNA hydrolases; d...   1 4   0.3795
STB5 YHR178W Activator of multidrug resistance genes, forms a heterodimer with Pdr1p; contain...   1 24   0.2681
PBP1 YGR178C Protein interacting with poly(A)-binding protein Pab1p; likely involved in contr...   1 8   0.3115
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex; associates with core polymera... RNA polymerase II holoenzyme/mediator subunit 1 25   0.0156
PRI1 YIR008C Subunit of DNA primase, which is required for DNA synthesis and double-strand br... DNA primase p48 polypeptide 1 13   0.3823
RMD8 YFR048W Cytosolic protein required for sporulation   1 5   0.3627
SAD1 YFR005C Conserved zinc-finger domain protein involved in pre-mRNA splicing, required for...   1 4   0.2649

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