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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:35
Sym Orf Description Function No All Z_score hyperg
STI1 YOR027W Hsp90 cochaperone, interacts with the Ssa group of the cytosolic Hsp70 chaperone... heat shock protein also induced by canavanine and entry into stationary phase 4 46   0.063
BUB1 YGR188C Protein kinase that forms a complex with Mad1p and Bub3p that is crucial in the ...   4 23   0
BUD14 YAR014C Protein involved in bud-site selection, Bud14p-Glc7p complex functions as a cort...   4 74   0.0016
SUP35 YDR172W Translation termination factor eRF3; altered protein conformation creates the [P... translation termination factor eRF3 4 72   0
CIN8 YEL061C Kinesin motor protein involved in mitotic spindle assembly and chromosome segreg...   4 18 -42.0623 0
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isome... cyclophilin 40|peptidyl-prolyl cis-trans isomerase (PPIase) 4 28   0.1407
YPT7 YML001W GTPase; GTP-binding protein of the rab family; required for homotypic fusion eve... GTP-binding protein|rab family 4 33   0.0143
KEL1 YHR158C Protein required for proper cell fusion and cell morphology; functions in a comp...   3 36   0.0005
PEP7 YDR323C Multivalent adaptor protein that facilitates vesicle-mediated vacuolar protein s... three zinc fingers; cysteine rich regions of amino acids are essential for function 3 14   0.2333
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding ... replication factor C subunit 4|similar to human RFC 40 kDa subunit 3 34   0.0355
SAK1 YER129W Upstream kinase for the SNF1 complex; partially redundant function with Elm1p an...   3 27   0
MRPS5 YBR251W Mitochondrial ribosomal protein of the small subunit ribosomal protein S5 (putative) 3 59   0
SRP72 YPL210C Core component of the signal recognition particle (SRP) ribonucleoprotein (RNP) ... signal recognition particle component 3 20   0.0001
CNS1 YBR155W TPR-containing co-chaperone; binds both Hsp82p (Hsp90) and Ssa1p (Hsp70) and sti...   3 31   0
  YMR124W     3 19   0.0023
GYL1 YMR192W Putative GTPase activating protein (GAP) that may have a role in polarized exocy...   3 18   0
CKB1 YGL019W Beta regulatory subunit of casein kinase 2, a Ser/Thr protein kinase with roles ... protein kinase CK2 beta subunit 3 83   0.135
PEX11 YOL147C Peroxisomal membrane protein required for peroxisome proliferation and medium-ch... peroxin|peroxisomal membrane protein 3 12 -54.9372 0
CDC6 YJL194W Essential ATP-binding protein required for DNA replication, component of the pre... pre-initiation complex component 3 36   0
SGT1 YOR057W Probable cochaperone, regulates activity of Cyr1p (adenylyl cyclase); involved i...   3 27   0
SLX9 YGR081C Protein of unknown function; deletion mutant has synthetic fitness defect with a...   3 20   0
SAE2 YGL175C Protein with a role in accurate meiotic and mitotic double-strand break repair; ...   2 13   0.28
RFC5 YBR087W Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding ... replication factor C subunit 5|similar to human RFC 38 kDa subunit 2 37   0.2077
POL30 YBR088C Proliferating cell nuclear antigen (PCNA), functions as the sliding clamp for DN... Proliferating Cell Nuclear Antigen (PCNA) 2 61   0
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding ... replication factor C subunit 2|similar to human RFC 37 kDa subunit 2 39   0.0104
RPB3 YIL021W RNA polymerase II third largest subunit B44, part of central core; similar to pr... RNA polymerase II 45 kDa subunit 2 87   0.0047
MUK1 YPL070W Protein of unknown function, localized to the cytoplasm; computational analysis ...   2 36   0.2001
VPS16 YPL045W Subunit of the homotypic vacuole fusion and vacuole protein sorting (HOPS) compl...   2 25   0.083
VPS3 YDR495C Cytoplasmic protein required for the sorting and processing of soluble vacuolar ...   2 19   0.2824
HNT1 YDL125C Adenosine 5--monophosphoramidase; interacts physically and genetically with Kin2...   2 9   0
RCO1 YMR075W Nuclear protein of unknown function   2 32   0.0262
VPS8 YAL002W Membrane-associated hydrophilic protein that interacts with the small GTPase, Vp... membrane-associated hydrophilic protein which contains a C-terminal cysteine-rich region that conforms to the H2 variant of the RING finger Zn2+ binding motif 2 19   0.0027
MUS81 YDR386W Helix-hairpin-helix protein, involved in DNA repair and replication fork stabili...   2 39   0
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, essentia...   2 102   0
PEP3 YLR148W Vacuolar peripheral membrane protein that promotes vesicular docking/fusion reac... vacuolar membrane protein 2 33   0.0237

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