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SONAR Targetspace for BENZTROPINEZ-score WebGraph NB WebGraph
Targetspace hs 286 0
Targetspace hs pval0.0266393442622951
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
RLM1 YPL089C MADS-box transcription factor, component of the protein kinase C-mediated MAP ki...   11 15   0.0524
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 10 39   0
MSG5 YNL053W Dual-specificity protein phosphatase required for maintenance of a low level of ... protein tyrosine phosphatase 10 16   0
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   10 26 -1.3533 0.14
MKK1 YOR231W Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... MAP kinase kinase (MEK) 10 38   0.1393
PAF1 YBR279W RNA polymerase II-associated protein, defines a large complex that is biochemica...   10 51 -1.9248 0
MKK2 YPL140C Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... protein kinase 9 33   0
BCK1 YJL095W Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinas... MEKK 9 143 -3.0468 0
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for... MAP kinase 9 21   0
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   9 34   0
SLT2 YHR030C Serine/threonine MAP kinase involved in regulating the maintenance of cell wall ...   7 98 -7.9698 0
STE20 YHL007C Signal transducing kinase of the PAK (p21-activated kinase) family, involved in ...   7 117   0
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 6 24 -0.0061 0
KIC1 YHR102W Protein kinase of the PAK/Ste20 kinase family, required for cell integrity possi...   5 22   0
SKG3 YLR187W Protein of unknown function; green fluorescent protein (GFP)-fusion protein loca...   5 16   0
SWI6 YLR182W Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1... transcription factor 5 36   0.1742
EBS1 YDR206W Protein of unknown function, contains a putative RNA recognition motif, deletion...   5 16   0
PDC6 YGR087C Minor isoform of pyruvate decarboxylase, key enzyme in alcoholic fermentation, d... pyruvate decarboxylase isozyme 5 9   0
ROM1 YGR070W GDP/GTP exchange protein (GEP) for Rho1p; mutations are synthetically lethal wit...   5 5   0
SIR3 YLR442C Silencing protein that interacts with Sir2p and Sir4p, and histone H3 and H4 tai... silencing regulator at HML, HMR, and telomeres 5 56   0.188
PRS2 YER099C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, his... ribose-phosphate pyrophosphokinase 5 10   0
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide ... Hsp70 family 5 16   0.1056
GAL7 YBR018C Galactose-1-phosphate uridyl transferase, synthesizes glucose-1-phosphate and UD... galactose-1-phosphate uridyl transferase 5 9   0
PRS3 YHL011C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, his... ribose-phosphate pyrophosphokinase 5 20   0
MPM1 YJL066C Mitochondrial membrane protein of unknown function, contains no hydrophobic stre...   5 11   0
FOL2 YGR267C GTP-cyclohydrolase I, catalyzes the first step in the folic acid biosynthetic pa... GTP-cyclohydrolase I 5 25   0
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 5 25 -6.3522 NAN
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54); contains...   5 23   0
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which cataly... isocitrate dehydrogenase 1 alpha-4-beta-4 subunit 5 17   0
DIG1 YPL049C Regulatory protein of unknown function, constitutively-expressed, involved in th... MAP kinase-associated protein 5 54   0
MSF1 YPR047W Mitochondrial phenylalanyl-tRNA synthetase alpha subunit, active as a monomer, u... phenylalanyl-tRNA synthetase alpha subunit 5 6   0
PTP3 YER075C Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 5 8   0
QCR2 YPR191W Subunit 2 of the ubiquinol cytochrome-c reductase complex, which is a component ... 40 kDa ubiquinol cytochrome-c reductase core protein 2 5 24   0
PRS4 YBL068W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, his... ribose-phosphate pyrophosphokinase 5 6   0
GCN3 YKR026C Alpha subunit of the translation initiation factor eIF2B, the guanine-nucleotide... eIF2B 34 kDa alpha subunit 5 52 -1.3278 0
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p; not func...   5 44   0
  YPL077C     5 22   0.0114
USE1 YGL098W Essential SNARE protein localized to the ER, involved in retrograde traffic from...   5 19   0
SOG2 YOR353C Protein required for cell morphogenesis and cell separation after mitosis   5 10   0
MKT1 YNL085W Protein that forms a complex with Pbp1p that may mediate posttranscriptional reg... retroviral protease signature protein 5 36   0.0748

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