Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for BENZTROPINEZ-score WebGraph NB WebGraph
Targetspace hs 286 0
Targetspace hs pval0.0266393442622951
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
  YKL161C     10 5   0.1116
RPI1 YIL119C Putative transcriptional regulator; overexpression suppresses the heat shock sen... ras inhibitor 10 9   0.0011
  YKL037W     9 12   0.0048
SIW14 YNL032W Tyrosine phosphatase that plays a role in actin filament organization and endocy... tyrosine phosphatase 9 16   0
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, requ... scaffold protein 8 41 -7.2555 NAN
IKI3 YLR384C Subunit of RNA polymerase II elongator histone acetyltransferase complex, involv...   8 80 -0.0651 0
FPS1 YLL043W Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) fa... glycerol channel protein 8 28   0.0002
KAR1 YNL188W Essential protein involved in karyogamy during mating and in spindle pole body d...   8 16   0.0215
PKC1 YBL105C Protein serine/threonine kinase essential for cell wall remodeling during growth...   8 102   0.0764
MID2 YLR332W O-glycosylated plasma membrane protein that acts as a sensor for cell wall integ...   7 46   0.0001
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   7 54   0
MYO2 YOR326W One of two type V myosins, involved in polarized distribution of mitochondria; r... class V myosin 7 104   0
ROT1 YMR200W Protein that may be involved in cell wall function; mutations in rot1 cause cell... membrane protein (putative) 7 27   0
PCL2 YDL127W G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to... G1 cyclin 7 19   0.0136
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase; identified as a high-copy number suppre... type 2C protein phosphatase 6 4   0.091
ELP4 YPL101W Elongator protein, part of the HAP subcomplex of Elongator, which is a six-subun... RNA polymerase II Elongator protein subunit 6 80   0
MKK2 YPL140C Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... protein kinase 6 7   0
KRE11 YGR166W Protein involved in biosynthesis of cell wall beta-glucans; subunit of the TRAPP...   6 62   0
URM1 YIL008W Ubiquitin-like protein with only weak sequence similarity to ubiquitin; depends ... ubiquitin-like protein 6 56   0
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation...   6 10   0.091
CYK3 YDL117W SH3-domain protein located in the mother-bud neck and the cytokinetic actin ring...   6 34   0.0454
PTC2 YER089C Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress ... protein phosphatase type 2C 6 28   0
RGD1 YBR260C GTPase-activating protein (RhoGAP) for Rho3p and Rho4p, possibly involved in con... GTPase activating protein (GAP) (putative) 5 22   0.0075
ERG7 YHR072W Lanosterol synthase, an essential enzyme that catalyzes the cyclization of squal... 2,3-oxidosqualene-lanosterol cyclase 5 5   0
GPI1 YGR216C Membrane protein involved in the synthesis of N-acetylglucosaminyl phosphatidyli...   5 4   0
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that functions to modulate Rhop1 activi...   5 26   0.0151
GPI16 YHR188C Transmembrane protein subunit of the glycosylphosphatidylinositol transamidase c... GPI transamidase component, human PIG-T homologue 5 3   0
RPC10 YHR143W-A RNA polymerase subunit, found in RNA polymerase complexes I, II, and III RNA polymerase II subunit 5 15   0
NCP1 YHR042W NADP-cytochrome P450 reductase; involved in ergosterol biosynthesis; associated ... NADP-cytochrome P450 reductase 5 11   0
RIM101 YHL027W Transcriptional repressor involved in the response to pH; required for alkaline ...   5 65   0.0168
YPS7 YDR349C Putative GPI-anchored aspartic protease, located in the cytoplasm and endoplasmi... GPI-anchored aspartic protease 5 5   0
SWI5 YDR146C Transcription factor that activates transcription of genes expressed in G1 phase... transcriptional activator 5 43   0.0114
  ETG5598     5 1   0
PTC3 YBL056W Type 2C protein phosphatase; dephosphorylates Hog1p (see also Ptc2p) to limit ma... protein phosphatase type 2C 5 11   0
ECM33 YBR078W GPI-anchored protein of unknown function, has a possible role in apical bud grow...   5 9   0.0067
ALG7 YBR243C UDP-N-acetyl-glucosamine-1-P transferase, transfers Glc-Nac-P from UDP-GlcNac to... UDP-N-acetyl-glucosamine-1-P transferase (GPT) 5 10   0
GPI11 YDR302W ER membrane protein involved in a late step of glycosylphosphatidylinositol (GPI...   5 2   0
TAF10 YDR167W Subunit (145 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II tra... TFIID subunit 5 10   0
SYP1 YCR030C Protein with a potential role in actin cytoskeletal organization; overexpression...   5 9   0
TPM1 YNL079C Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments... tropomyosin I 5 46   0

Service provided by the Mike Tyers Laboratory