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SONAR Targetspace for BENZTROPINEZ-score WebGraph NB WebGraph
Targetspace hs 286 0
Targetspace hs pval0.0266393442622951
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:34
Sym Orf Description Function No All Z_score hyperg
MID2 YLR332W O-glycosylated plasma membrane protein that acts as a sensor for cell wall integ...   12 147   0.0079
PIR1 YKL164C O-glycosylated protein required for cell wall stability; attached to the cell wa...   12 36   0
HPT1 YDR399W Dimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation ... hypoxanthine guanine phosphoribosyltransferase 11 119   0
SDP1 YIL113W Stress-inducible dual-specificity MAP kinase phosphatase, negatively regulates S...   10 13   0
LST4 YKL176C Protein possibly involved in a post-Golgi secretory pathway; required for the tr...   10 128   0
  YKL161C     10 35   0.1116
MKK2 YPL140C Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... protein kinase 9 66   0
MSG5 YNL053W Dual-specificity protein phosphatase required for maintenance of a low level of ... protein tyrosine phosphatase 9 60   0
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 9 95   0
  YKL037W     9 16   0.0048
BUD6 YLR319C Actin- and formin-interacting protein, involved in actin cable nucleation and po...   9 86   0
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for... MAP kinase 8 36   0
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage, interacts...   8 75   0.0883
MKK1 YOR231W Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... MAP kinase kinase (MEK) 8 96   0.1064
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton o... rho GTPase activating protein (GAP) 8 84   0
KAR1 YNL188W Essential protein involved in karyogamy during mating and in spindle pole body d...   8 23   0.0215
PCL2 YDL127W G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to... G1 cyclin 7 36   0.0136
PTP2 YOR208W Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 7 51   0
PMA2 YPL036W Plasma membrane H+-ATPase, isoform of Pma1p, involved in pumping protons out of ... plasma membrane ATPase 7 114   0
UBP14 YBR058C Ubiquitin-specific protease that specifically disassembles unanchored ubiquitin ... ubiquitin-specific protease 7 148   0.0061
GSH1 YJL101C Gamma glutamylcysteine synthetase, catalyzes the first step in the gamma-glutamy... gamma-glutamylcysteine synthetase 6 150   0
MSC2 YDR205W Member of the cation diffusion facilitator family, localizes to the endoplasmic ...   6 24   0
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation...   6 31   0.091
PGM1 YKL127W Phosphoglucomutase, minor isoform; catalyzes the conversion from glucose-1-phosp... phosphoglucomutase minor isoform 6 47   0.1144
RPI1 YIL119C Putative transcriptional regulator; overexpression suppresses the heat shock sen... ras inhibitor 6 46   0.0643
KRE11 YGR166W Protein involved in biosynthesis of cell wall beta-glucans; subunit of the TRAPP...   6 139   0
  YDR348C     6 31   0
ZDS1 YMR273C Protein that interacts with silencing proteins at the telomere, involved in tran...   6 128   0.1704
CWH43 YCR017C Putative sensor/transporter protein involved in cell wall biogenesis; contains 1...   6 77   0.0879
FOL2 YGR267C GTP-cyclohydrolase I, catalyzes the first step in the folic acid biosynthetic pa... GTP-cyclohydrolase I 5 26   0
ERG7 YHR072W Lanosterol synthase, an essential enzyme that catalyzes the cyclization of squal... 2,3-oxidosqualene-lanosterol cyclase 5 30   0
GPI11 YDR302W ER membrane protein involved in a late step of glycosylphosphatidylinositol (GPI...   5 2   0
TAF10 YDR167W Subunit (145 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II tra... TFIID subunit 5 89   0
PRS2 YER099C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, his... ribose-phosphate pyrophosphokinase 5 15   0

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