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SONAR Targetspace for CHAULMOOGRIC ACIDZ-score WebGraph NB WebGraph
Targetspace hs 325 137
Targetspace hs pval0.0394190871369290.14645308924485
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:30
Sym Orf Description Function No All Z_score hyperg
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 45 145 -1.7925 NAN
GAS1 YMR307W Beta-1.3-glucanosyltransferase, required for cell wall assembly; localizes to th... cell surface glycoprotein 115-120 kDa 27 111 1.2980 0
CNB1 YKL190W Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulate... calcineurin regulatory B subunit|type 2B protein phosphatase 24 81 -8.7105 0
RVS167 YDR388W Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) involved in reg... cytoskeletal protein (putative) 23 108 -1.3264 0
RUD3 YOR216C Golgi matrix protein involved in the structural organization of the cis-Golgi; i...   22 100   NAN
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   22 54   NAN
MYO2 YOR326W One of two type V myosins, involved in polarized distribution of mitochondria; r... class V myosin 22 104   0
PCL2 YDL127W G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to... G1 cyclin 21 19   0
PCL1 YNL289W Pho85 cyclin of the Pcl1,2-like subfamily, involved in entry into the mitotic ce... G1 cyclin|associates with PHO85 20 25   0.0001
ARP2 YDL029W Essential component of the Arp2/3 complex, which is a highly conserved actin nuc... actin related protein 20 99   NAN
ARC40 YBR234C Essential subunit of the ARP2/3 complex, which is required for the motility and ...   19 44   NAN
CHS5 YLR330W Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p...   19 107 -8.6550 NAN
OPI3 YJR073C Phospholipid methyltransferase (methylene-fatty-acyl-phospholipid synthase), cat... unsaturated phospholipid N-methyltransferase 18 126   NAN
SSD1 YDR293C Protein with a role in maintenance of cellular integrity, interacts with compone...   18 72   0
CCW12 YLR110C Cell wall protein, mutants are defective in mating and agglutination, expression... cell wall mannoprotein 18 115   0
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alt... 1,3-beta-D-glucan synthase 18 126 -2.7704 0
HOC1 YJR075W Alpha-1,6-mannosyltransferase involved in cell wall mannan biosynthesis; subunit... mannosyltransferase (putative) 17 64 -1.0137 0.116
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic; regulates potassiu... ADP-ribosylation factor-like protein 1 17 141   0
SWF1 YDR126W Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on a...   17 48   0.0071
ROT2 YBR229C Glucosidase II catalytic subunit required for normal cell wall synthesis; mutati... glucosidase II 17 92 0.2547 0.0839
KRE11 YGR166W Protein involved in biosynthesis of cell wall beta-glucans; subunit of the TRAPP...   17 62   0
RVS161 YCR009C Amphiphysin-like lipid raft protein; subunit of a complex (Rvs161p-Rvs167p) that...   17 140   0
VPS8 YAL002W Membrane-associated hydrophilic protein that interacts with the small GTPase, Vp... membrane-associated hydrophilic protein which contains a C-terminal cysteine-rich region that conforms to the H2 variant of the RING finger Zn2+ binding motif 16 38   0.0073
SYS1 YJL004C Integral membrane protein of the Golgi required for targeting of the Arf-like GT...   16 41   0
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regul...   16 93 -2.0877 0.1186
OPI1 YHL020C Transcriptional regulator of a variety of genes; phosphorylation by protein kina...   15 22   0
KAR1 YNL188W Essential protein involved in karyogamy during mating and in spindle pole body d...   15 16   0
  YKL161C     15 5   0.0086
UBP3 YER151C Ubiquitin-specific protease that interacts with Bre5p to co-regulate anterograde... ubiquitin-specific protease 15 99   0.012
  YKL037W     15 12   0

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