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SONAR Targetspace for EPIANDROSTERONEZ-score WebGraph NB WebGraph
Targetspace hs 297 217
Targetspace hs pval0.314960629921260.22794117647059
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:34
Sym Orf Description Function No All Z_score hyperg
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   16 54   NAN
  YKL161C     15 5   0.0086
  YKL037W     14 12   0
OPI1 YHL020C Transcriptional regulator of a variety of genes; phosphorylation by protein kina...   14 22   0
KAR1 YNL188W Essential protein involved in karyogamy during mating and in spindle pole body d...   14 16   0
SWF1 YDR126W Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on a...   12 48   0.0002
PCL2 YDL127W G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to... G1 cyclin 12 19   0
MOB1 YIL106W Component of the mitotic exit network; associates with and is required for the a...   12 22   0
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 11 145 -3.0908 NAN
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation...   10 31 -3.4566 0.1159
CDC34 YDR054C Ubiquitin-conjugating enzyme or E2; together with Skp1p, Rbx1p, Cdc53p, and an F... ubiquitin-conjugating enzyme 10 58   0
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase, component of the cAMP-dependent prot... high affinity cAMP phosphodiesterase 10 62   0.1415
CNB1 YKL190W Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulate... calcineurin regulatory B subunit|type 2B protein phosphatase 10 81 -6.1739 0
SSD1 YDR293C Protein with a role in maintenance of cellular integrity, interacts with compone...   10 72   0.0658
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation...   10 10   0.1342
RPI1 YIL119C Putative transcriptional regulator; overexpression suppresses the heat shock sen... ras inhibitor 10 9   0.0011
PCL1 YNL289W Pho85 cyclin of the Pcl1,2-like subfamily, involved in entry into the mitotic ce... G1 cyclin|associates with PHO85 10 25   0.1213
MID2 YLR332W O-glycosylated plasma membrane protein that acts as a sensor for cell wall integ...   10 46   0.0018
CDC15 YAR019C Protein kinase of the Mitotic Exit Network that is localized to the spindle pole... protein kinase domain 10 66   0.0017
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of the ER membrane, catalyzes th... dolichol phosphate mannose synthase 10 8   0
SIW14 YNL032W Tyrosine phosphatase that plays a role in actin filament organization and endocy... tyrosine phosphatase 10 16   0
RIM101 YHL027W Transcriptional repressor involved in the response to pH; required for alkaline ...   9 65   0.1095
BUD6 YLR319C Actin- and formin-interacting protein, involved in actin cable nucleation and po...   9 36   0
PKR1 YMR123W Protein of unknown function; overproduction confers resistance to Pichia farinos...   9 32   0
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that functions to modulate Rhop1 activi...   9 26   0.1085
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p), a membrane-associated co...   8 24   0
GGA2 YHR108W Golgi-localized protein with homology to gamma-adaptin, interacts with and regul... ARF-binding protein 8 20   0
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely... rho GTPase 8 8   0.0206
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   8 12   0.0002
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II tran... TFIID subunit 8 116   0.0361
MKK1 YOR231W Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... MAP kinase kinase (MEK) 8 26 -3.1753 0.1064
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage, interacts...   7 25   0.1324
HOS2 YGL194C Histone deacetylase required for gene activation via specific deacetylation of l...   7 74   0
KRE11 YGR166W Protein involved in biosynthesis of cell wall beta-glucans; subunit of the TRAPP...   7 62   0

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