Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for DEHYDROABIETAMIDEZ-score WebGraph NB WebGraph
Targetspace hs 196 288
Targetspace hs pval0.0525210084033610.24009900990099
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:37
Sym Orf Description Function No All Z_score hyperg
ROM1 YGR070W GDP/GTP exchange protein (GEP) for Rho1p; mutations are synthetically lethal wit...   2 31   0.018
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that functions to modulate Rhop1 activi...   2 37   0.0004
ACK1 YDL203C Hypothetical protein a TRP/SEL-1 domain containing protein 2 53   0
  YBR141C     1 116   0
PTA1 YAL043C Subunit of holo-CPF, a multiprotein complex and functional homolog of mammalian ... cleavage factor II (CF II) component|polyadenylation factor I (PF I) 1 127   0.0054
TSC10 YBR265W 3-ketosphinganine reductase, catalyzes the second step in phytosphingosine synth... 3-ketosphinganine reductase 1 25   0
ATS1 YAL020C Protein with a potential role in regulatory interactions between microtubules an...   1 106   0.1337
PKH1 YDR490C Serine/threonine protein kinase involved in sphingolipid-mediated signaling path...   1 52   0
RGA2 YDR379W GTPase-activating protein for the polarity-establishment protein Cdc42p; implica... Rho-GTPase Activating Protein 1 43   0.2106
GGA1 YDR358W Golgi-localized protein with homology to gamma-adaptin, interacts with and regul... ARF-binding protein 1 72   0.0405
PSK2 YOL045W One of two (see also PSK1) PAS domain containing S/T protein kinases; regulates ... PAS kinase 1 120   0.3333
PDR3 YBL005W Transcriptional activator of the pleiotropic drug resistance network, regulates ...   1 45   0
LRG1 YDL240W Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signalin... similar to LIM-domain proteins and to rho/rac GTPase-activating family of proteins 1 46   0.0516
NDE2 YDL085W Mitochondrial external NADH dehydrogenase, catalyzes the oxidation of cytosolic ... Type II NAD(P)H:quinone oxidoreductase 1 31   0
WSC2 YNL283C Partially redundant sensor-transducer of the stress-activated PKC1-MPK1 signalin... contains novel cysteine motif|integral membrane protein (putative)|similar to SLG1 (WSC1), WSC3 and WSC4 1 39   0
NUP85 YJR042W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), required for... nuclear pore complex subunit 1 43   0
PDR1 YGL013C Zinc cluster protein that is a master regulator involved in recruiting other zin... zinc finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type 1 101   0.2106
PHM8 YER037W Protein of unknown function, expression is induced by low phosphate levels and b...   1 27   0
HSF1 YGL073W Trimeric heat shock transcription factor, activates multiple genes in response t... heat shock transcription factor 1 48   0.0659
AVO1 YOL078W Component of a membrane-bound complex containing the Tor2p kinase and other prot...   1 36   0.1726
MDJ2 YNL328C Constituent of the mitochondrial import motor associated with the presequence tr... chaperonin 1 19   0
STB1 YNL309W Protein with a role in regulation of MBF-specific transcription at Start, phosph...   1 68   0.0533
CDC33 YOL139C Cytoplasmic mRNA cap binding protein; the eIF4E-cap complex is responsible for m... mRNA cap binding protein eIF-4E 1 107   0.3776
PFY1 YOR122C Profilin, actin- and phosphatidylinositol 4,5-bisphosphate-binding protein, play... profilin 1 35   0.3089
BSP1 YPR171W Adapter that links synaptojanins Inp2p and Inp53p to the cortical actin cytoskel...   1 75   0.1726
ERI1 YPL096C-A Endoplasmic reticulum membrane protein that binds to and inhibits GTP-bound Ras2...   1 48   0
MKK1 YOR231W Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... MAP kinase kinase (MEK) 1 96 -3.1144 0.0002
FAR11 YNL127W Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway ...   1 104   0.0694
  YNL010W     1 56   0
SDA1 YGR245C Highly conserved nuclear protein required for actin cytoskeleton organization an...   1 93   0.1155
MRPL9 YGR220C Mitochondrial ribosomal protein of the large subunit   1 58   0
GPI1 YGR216C Membrane protein involved in the synthesis of N-acetylglucosaminyl phosphatidyli...   1 57   0.1917
RPI1 YIL119C Putative transcriptional regulator; overexpression suppresses the heat shock sen... ras inhibitor 1 46   0.1288
LCB3 YJL134W Long-chain base-1-phosphate phosphatase, regulates ceramide and long-chain base ... dihydrosphingosine-1-phosphate phophatase 1 71 -0.9320 0.2039
DNF3 YMR162C Non-essential P-type ATPase involved in aminophospholipid translocation, localiz... Potential aminophospholipid translocase 1 16   0
DPH5 YLR172C Methyltransferase required for synthesis of diphthamide, which is a modified his...   1 102   0
STR2 YJR130C Cystathionine gamma-synthase, converts cysteine into cystathionine cystathionine gamma-synthase 1 51   0.0197

Service provided by the Mike Tyers Laboratory