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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:38
Sym Orf Description Function No All Z_score hyperg
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 13 24 -21.5699 0
SLT2 YHR030C Serine/threonine MAP kinase involved in regulating the maintenance of cell wall ...   12 98 -17.2492 0
SWI6 YLR182W Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1... transcription factor 12 36   0.0081
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   10 26 -21.1938 0.14
RLM1 YPL089C MADS-box transcription factor, component of the protein kinase C-mediated MAP ki...   10 15   0.0832
MSG5 YNL053W Dual-specificity protein phosphatase required for maintenance of a low level of ... protein tyrosine phosphatase 10 16   0
MKK1 YOR231W Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... MAP kinase kinase (MEK) 10 38   0.1393
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 10 39   0
MKK2 YPL140C Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... protein kinase 10 33   0
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for... MAP kinase 10 21   0
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 10 25 -12.4320 NAN
BCK1 YJL095W Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinas... MEKK 10 143 -11.4308 0
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   10 34   0
PAF1 YBR279W RNA polymerase II-associated protein, defines a large complex that is biochemica...   10 51 -1.6289 0
SDP1 YIL113W Stress-inducible dual-specificity MAP kinase phosphatase, negatively regulates S...   7 5   0
TOR2 YKL203C PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha...   7 89   0.0002
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase), catalyzes the rapid exchange of o... inorganic pyrophosphatase 7 41   0
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54); contains...   7 23   0
EGD2 YHR193C Alpha subunit of the heteromeric nascent polypeptide-associated complex (NAC) in... GAL4 enhancer protein|nascent-polypeptide-associated complex human alpha NAC subunit homolog 6 33   0
KIN2 YLR096W Serine/threonine protein kinase involved in regulation of exocytosis; localizes ...   6 109   0
ADA2 YDR448W Transcription coactivator, component of the ADA and SAGA transcriptional adaptor... transcription factor 6 108   0.0003
  YPL077C     6 22   0.0026
TOR1 YJR066W PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha... phosphatidylinositol kinase homolog 6 104   0.0097
KIC1 YHR102W Protein kinase of the PAK/Ste20 kinase family, required for cell integrity possi...   5 22   0
LYS12 YIL094C Homo-isocitrate dehydrogenase, an NAD-linked mitochondrial enzyme required for t... homo-isocitrate dehydrogenase 5 51   0
OYE2 YHR179W Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), ho... NAPDH dehydrogenase (old yellow enzyme), isoform 2 5 25   0
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide ... Hsp70 family 5 16   0.1056
PRS1 YKL181W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, his... ribose-phosphate pyrophosphokinase 5 25   0
TIF2 YJL138C Translation initiation factor eIF4A, identical to Tif1p; DEA(D/H)-box RNA helica... translation initiation factor eIF4A subunit 5 73   0
MPM1 YJL066C Mitochondrial membrane protein of unknown function, contains no hydrophobic stre...   5 11   0
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerat... 6-phosphogluconate dehydrogenase 5 29   0
PRE3 YJL001W 20S proteasome beta-type subunit, responsible for cleavage after acidic residues... 20S proteasome subunit 5 39   0
  YFR038W     5 7   0.0188
PRS3 YHL011C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, his... ribose-phosphate pyrophosphokinase 5 20   0
MTW1 YAL034W-A Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p...   5 50   0
LEO1 YOR123C Component of the Paf1 complex, which associates with RNA polymerase II and is in...   5 38   0
CTR9 YOL145C Component of the Paf1p complex, which is a large complex that binds to and modul...   5 49   0.1862
RTF1 YGL244W Subunit of the RNA polymerase II-associated Paf1 complex; directly or indirectly... nuclear protein 5 36   0.0954

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