Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for USNIC ACIDZ-score WebGraph NB WebGraph
Targetspace hs 106 102
Targetspace hs pval0.103524229074890.14123006833713
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
PTP2 YOR208W Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 8 28   0
FUS3 YBL016W Mitogen-activated protein kinase involved in mating pheromone response; activate... CDC28/cdc2 related protein kinase 6 32   0
SGD1 YLR336C Essential nuclear protein with a possible role in the osmoregulatory glycerol re...   6 4   0
MSB2 YGR014W Mucin family member at the head of the Cdc42p- and MAP kinase-dependent filament... integral membrane protein (putative) 6 20   0
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways... MAP kinase 6 26   0
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p), a complex that regulates g...   5 16   0.014
HLR1 YDR528W Protein involved in regulation of cell wall composition and integrity and respon...   4 7   0
TUP1 YCR084C General repressor of transcription, forms complex with Cyc8p, involved in the es...   4 16   0
GTR2 YGR163W Cytoplasmic GTP binding protein, negative regulator of the Ran/Tc4 GTPase cycle ... similar to Gtr1|small GTPase (putative) 4 16   0
GCN4 YEL009C Transcriptional activator of amino acid biosynthetic genes in response to amino ... transcriptional activator of amino acid biosynthetic genes 4 40   0
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 4 59   0
STE4 YOR212W G protein beta subunit, forms a dimer with Ste18p to activate the mating signali... G protein beta subunit|coupled to mating factor receptor 4 42   0
  YPR045C     4 14   0
GUT2 YIL155C Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by bot... glycerol-3-phosphate dehydrogenase 4 10   0
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which cataly... NAD-dependent isocitrate dehydrogenase 4 15 -1.2002 0.0489
STE11 YLR362W Signal transducing MEK kinase involved in pheromone response and pseudohyphal/in...   4 70   0.0003
SKO1 YNL167C Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family that for...   4 15   0
CYC8 YBR112C General transcriptional co-repressor, acts together with Tup1p; also acts as par...   4 24   0.0308
YPK1 YKL126W Serine/threonine protein kinase required for receptor-mediated endocytosis; invo... 76.5 kDa serine/threonine protein kinase|similarity to protein kinase C, is 90% identical to Ypk2p 4 40   0
PBS2 YJL128C MAP kinase kinase that plays a pivotal role in the osmosensing signal-transducti... MAP kinase kinase (MEK)|may act as a scaffolding protein for Sho1p, Ste11p, and Hog1p 3 38   0
STE5 YDR103W Scaffold protein that, in response to pheromone, shuttles from the nucleus to th...   3 26   0
CDC10 YCR002C Component of the septin ring of the mother-bud neck that is required for cytokin... septin 3 14   0.0017
OAC1 YKL120W Mitochondrial inner membrane transporter, transports oxaloacetate, sulfate, and ... oxaloacetate transport protein 3 12   0
TEC1 YBR083W Transcription factor required for full Ty1 epxression, Ty1-mediated gene activat... TEA/ATTS DNA-binding domain family transcription factor 3 17   0.225
HKR1 YDR420W Serine/threonine rich cell surface protein that contains an EF hand motif; invol... contains EF hand motif|type I transmembrane protein 3 25   0.0002
VAC8 YEL013W Phosphorylated vacuolar membrane protein that interacts with Atg13p, required fo...   3 13   0.2198
PEP12 YOR036W Target membrane receptor (t-SNARE) for vesicular intermediates traveling between... c-terminal TMD|integral membrane protein 3 33   0.1085
SSK1 YLR006C Cytoplasmic response regulator, part of a two-component signal transducer that m... two-component signal transducer that with Sln1p regulates osmosensing MAP kinase cascade(suppressor of sensor kinase) 3 23   0
ARR3 YPR201W Arsenite transporter of the plasma membrane, required for resistance to arsenic ...   3 7   0
PDR17 YNL264C Phosphatidylinositol transfer protein (PITP), downregulates Plb1p-mediated turno... Pdr16p homolog|Sec14p homolog 3 11   0.0019
PTP3 YER075C Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 3 13   0
IRE1 YHR079C Serine-threonine kinase and endoribonuclease; transmembrane protein that initiat... endoribonuclease|serine-threonine kinase|transmembrane protein 3 49 -12.2788 0.0898
YPD1 YDL235C Phosphorelay intermediate protein, phosphorylated by the plasma membrane sensor ... two-component phosphorelay intermediate 3 5   0
RSC9 YML127W One of 15 subunits of the -Remodel the Structure of Chromatin- (RSC) complex; DN...   3 13   0.0021
SLM4 YBR077C Component of the EGO complex, which is involved in the regulation of microautoph...   3 10   0.0001
SHO1 YER118C Transmembrane osmosensor, participates in activation of both the Cdc42p- and MAP... transmembrane osmosensor 3 17   0
MSG5 YNL053W Dual-specificity protein phosphatase required for maintenance of a low level of ... protein tyrosine phosphatase 3 14   0.0005
ACP1 YKL192C Mitochondrial matrix acyl carrier protein, involved in biosynthesis of octanoate... acyl carrier protein 3 4   0
SDP1 YIL113W Stress-inducible dual-specificity MAP kinase phosphatase, negatively regulates S...   3 1   0
ARR1 YPR199C Transcriptional activator of the bZIP family, required for transcription of gene...   3 2   0

Service provided by the Mike Tyers Laboratory