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SONAR Targetspace for USNIC ACIDZ-score WebGraph NB WebGraph
Targetspace hs 106 102
Targetspace hs pval0.103524229074890.14123006833713
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description⇓ Function No All Z_score hyperg
SHO1 YER118C Transmembrane osmosensor, participates in activation of both the Cdc42p- and MAP... transmembrane osmosensor 3 17   0
ARR1 YPR199C Transcriptional activator of the bZIP family, required for transcription of gene...   3 2   0
GCN4 YEL009C Transcriptional activator of amino acid biosynthetic genes in response to amino ... transcriptional activator of amino acid biosynthetic genes 4 40   0
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 4 59   0
TEC1 YBR083W Transcription factor required for full Ty1 epxression, Ty1-mediated gene activat... TEA/ATTS DNA-binding domain family transcription factor 3 17   0.225
PEP12 YOR036W Target membrane receptor (t-SNARE) for vesicular intermediates traveling between... c-terminal TMD|integral membrane protein 3 33   0.1085
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which cataly... NAD-dependent isocitrate dehydrogenase 4 15 -1.2002 0.0489
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p), a complex that regulates g...   5 16   0.014
SDP1 YIL113W Stress-inducible dual-specificity MAP kinase phosphatase, negatively regulates S...   3 1   0
STE11 YLR362W Signal transducing MEK kinase involved in pheromone response and pseudohyphal/in...   4 70   0.0003
HKR1 YDR420W Serine/threonine rich cell surface protein that contains an EF hand motif; invol... contains EF hand motif|type I transmembrane protein 3 25   0.0002
YPK1 YKL126W Serine/threonine protein kinase required for receptor-mediated endocytosis; invo... 76.5 kDa serine/threonine protein kinase|similarity to protein kinase C, is 90% identical to Ypk2p 4 40   0
IRE1 YHR079C Serine-threonine kinase and endoribonuclease; transmembrane protein that initiat... endoribonuclease|serine-threonine kinase|transmembrane protein 3 49 -12.2788 0.0898
STE5 YDR103W Scaffold protein that, in response to pheromone, shuttles from the nucleus to th...   3 26   0
HLR1 YDR528W Protein involved in regulation of cell wall composition and integrity and respon...   4 7   0
PTP2 YOR208W Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 8 28   0
PTP3 YER075C Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 3 13   0
VAC8 YEL013W Phosphorylated vacuolar membrane protein that interacts with Atg13p, required fo...   3 13   0.2198
YPD1 YDL235C Phosphorelay intermediate protein, phosphorylated by the plasma membrane sensor ... two-component phosphorelay intermediate 3 5   0
PDR17 YNL264C Phosphatidylinositol transfer protein (PITP), downregulates Plb1p-mediated turno... Pdr16p homolog|Sec14p homolog 3 11   0.0019
RSC9 YML127W One of 15 subunits of the -Remodel the Structure of Chromatin- (RSC) complex; DN...   3 13   0.0021
MSB2 YGR014W Mucin family member at the head of the Cdc42p- and MAP kinase-dependent filament... integral membrane protein (putative) 6 20   0
FUS3 YBL016W Mitogen-activated protein kinase involved in mating pheromone response; activate... CDC28/cdc2 related protein kinase 6 32   0
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways... MAP kinase 6 26   0
ACP1 YKL192C Mitochondrial matrix acyl carrier protein, involved in biosynthesis of octanoate... acyl carrier protein 3 4   0
OAC1 YKL120W Mitochondrial inner membrane transporter, transports oxaloacetate, sulfate, and ... oxaloacetate transport protein 3 12   0
GUT2 YIL155C Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by bot... glycerol-3-phosphate dehydrogenase 4 10   0
PBS2 YJL128C MAP kinase kinase that plays a pivotal role in the osmosensing signal-transducti... MAP kinase kinase (MEK)|may act as a scaffolding protein for Sho1p, Ste11p, and Hog1p 3 38   0
CYC8 YBR112C General transcriptional co-repressor, acts together with Tup1p; also acts as par...   4 24   0.0308
TUP1 YCR084C General repressor of transcription, forms complex with Cyc8p, involved in the es...   4 16   0
STE4 YOR212W G protein beta subunit, forms a dimer with Ste18p to activate the mating signali... G protein beta subunit|coupled to mating factor receptor 4 42   0
SGD1 YLR336C Essential nuclear protein with a possible role in the osmoregulatory glycerol re...   6 4   0
MSG5 YNL053W Dual-specificity protein phosphatase required for maintenance of a low level of ... protein tyrosine phosphatase 3 14   0.0005
SSK1 YLR006C Cytoplasmic response regulator, part of a two-component signal transducer that m... two-component signal transducer that with Sln1p regulates osmosensing MAP kinase cascade(suppressor of sensor kinase) 3 23   0
GTR2 YGR163W Cytoplasmic GTP binding protein, negative regulator of the Ran/Tc4 GTPase cycle ... similar to Gtr1|small GTPase (putative) 4 16   0
CDC10 YCR002C Component of the septin ring of the mother-bud neck that is required for cytokin... septin 3 14   0.0017
SLM4 YBR077C Component of the EGO complex, which is involved in the regulation of microautoph...   3 10   0.0001
SKO1 YNL167C Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family that for...   4 15   0
ARR3 YPR201W Arsenite transporter of the plasma membrane, required for resistance to arsenic ...   3 7   0
  YPR045C     4 14   0

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