Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for TESTOSTERONE PROPIONATEZ-score WebGraph NB WebGraph
Targetspace hs 323 122
Targetspace hs pval0.56074766355140.24626865671642
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:31
Sym Orf Description Function No All Z_score hyperg
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 47 145 -3.7336 NAN
MYO2 YOR326W One of two type V myosins, involved in polarized distribution of mitochondria; r... class V myosin 40 104   0
GAS1 YMR307W Beta-1.3-glucanosyltransferase, required for cell wall assembly; localizes to th... cell surface glycoprotein 115-120 kDa 37 111 -0.7790 0
PCL1 YNL289W Pho85 cyclin of the Pcl1,2-like subfamily, involved in entry into the mitotic ce... G1 cyclin|associates with PHO85 36 25   0
PCL2 YDL127W G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to... G1 cyclin 34 19   0
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   34 54   NAN
RVS167 YDR388W Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) involved in reg... cytoskeletal protein (putative) 32 108 -1.0428 NAN
CCW12 YLR110C Cell wall protein, mutants are defective in mating and agglutination, expression... cell wall mannoprotein 31 115   0
ARP2 YDL029W Essential component of the Arp2/3 complex, which is a highly conserved actin nuc... actin related protein 30 99   NAN
ARC40 YBR234C Essential subunit of the ARP2/3 complex, which is required for the motility and ...   29 44   NAN
CNB1 YKL190W Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulate... calcineurin regulatory B subunit|type 2B protein phosphatase 27 81 -2.0598 0
CHS5 YLR330W Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p...   27 107 -8.7177 NAN
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alt... 1,3-beta-D-glucan synthase 24 126 -7.2724 0
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 24 140 -3.2511 0
UBP3 YER151C Ubiquitin-specific protease that interacts with Bre5p to co-regulate anterograde... ubiquitin-specific protease 23 99   0.107
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase, component of the cAMP-dependent prot... high affinity cAMP phosphodiesterase 23 62   0.0001
RVS161 YCR009C Amphiphysin-like lipid raft protein; subunit of a complex (Rvs161p-Rvs167p) that...   22 140   0
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   22 71 -9.6089 0.0003
TPM1 YNL079C Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments... tropomyosin I 22 46   0.0058
MID2 YLR332W O-glycosylated plasma membrane protein that acts as a sensor for cell wall integ...   21 46   0.1066
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, requ... scaffold protein 21 41 -6.1139 NAN
YUR1 YJL139C Mannosyltransferase of the KTR1 family, involved in protein N-glycosylation; loc... mannosyltransferase 20 29   0
  YKL037W     20 12   0
CHS6 YJL099W Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p...   20 54   NAN
  YKL161C     20 5   0.0001
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that functions to modulate Rhop1 activi...   20 26   0.0044
KAR1 YNL188W Essential protein involved in karyogamy during mating and in spindle pole body d...   20 16   0
SWF1 YDR126W Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on a...   20 48   0.0284
CHS3 YBR023C Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to c... chitin synthase 3 19 93 -6.1060 NAN
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely... rho GTPase 19 8   0
OPI1 YHL020C Transcriptional regulator of a variety of genes; phosphorylation by protein kina...   19 22   0

Service provided by the Mike Tyers Laboratory