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SONAR Targetspace for SPHONDINZ-score WebGraph NB WebGraph
Targetspace hs 124 335
Targetspace hs pval0.0915032679738560.15437788018433
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:36
Sym Orf Description Function No All Z_score hyperg
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition; structurally an... DNA helicase 9 93   0.0681
HST3 YOR025W Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved alo...   7 74   0.0007
NPT1 YOR209C Nicotinate phosphoribosyltransferase, acts in the salvage pathway of NAD+ biosyn... nicotinate phosphoribosyltransferase 6 142   0.0001
PIF1 YML061C DNA helicase involved in telomere formation and elongation; acts as a catalytic ... 5--3- DNA helicase 6 104   0.1635
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on... compass (complex proteins associated with Set1p) component 6 74   0.0224
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length... DNA binding protein 6 71   0.1502
APN1 YKL114C Major apurinic/apyrimidinic endonuclease, 3--repair diesterase involved in repai... major apurinic/apyrimidinic endonuclease/3--repair diesterase 5 62   0.1552
CDC2 YDL102W Catalytic subunit of DNA polymerase delta; required for chromosomal DNA replicat... DNA polymerase III catalytic (delta) subunit 5 90   0.0504
SEN1 YLR430W Nuclear protein, putative helicase required for processing of tRNAs, rRNAs, and ... nuclear-localized tRNA splicing complex component 5 16   0
SIR3 YLR442C Silencing protein that interacts with Sir2p and Sir4p, and histone H3 and H4 tai... silencing regulator at HML, HMR, and telomeres 5 54   0.188
POL30 YBR088C Proliferating cell nuclear antigen (PCNA), functions as the sliding clamp for DN... Proliferating Cell Nuclear Antigen (PCNA) 5 78   0.0005
SPP1 YPL138C Subunit of COMPASS (Set1C), a complex which methylates histone H3 on lysine 4 an... compass (complex proteins associated with Set1p) component 4 35   0.1445
MEC3 YLR288C DNA damage and meiotic pachytene checkpoint protein; subunit of a heterotrimeric...   4 71   0.0009
TOA2 YKL058W TFIIA small subunit; involved in transcriptional activation, acts as antirepress... beta|transcription factor IIA subunit 4 11   0.0007
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p), cleaves single-stranded DNA duri... UV endonuclease 4 97   0.008
CDC6 YJL194W Essential ATP-binding protein required for DNA replication, component of the pre... pre-initiation complex component 4 64   0.0001
ORC5 YNL261W Subunit of the origin recognition complex, which directs DNA replication by bind... ATP-binding site (putative)|origin recognition complex fifth largest subunit 4 41   0.0005
ISW1 YBR245C Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodelin... ATPase component of a four subunit chromatin remodeling complex 4 96   0.1698
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 ... compass (complex proteins associated with Set1p) component 4 41   0.0105
RMI1 YPL024W Involved in response to DNA damage; null mutants have increased rates of recombi...   4 44   0.0017
URA7 YBL039C Major CTP synthase isozyme (see also URA8), catalyzes the ATP-dependent transfer... CTP synthase 4 24   0
NUP60 YAR002W Subunit of the nuclear pore complex (NPC), functions to anchor Nup2p to the NPC ... nuclear pore complex subunit 4 97   0
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex; deletion phenot...   4 59   0.1869
ARG2 YJL071W Acetylglutamate synthase (glutamate N-acetyltransferase), mitochondrial enzyme t... acetylglutamate synthase 4 22   0
POL2 YNL262W Catalytic subunit of DNA polymerase epsilon, one of the major chromosomal DNA re... DNA polymerase II 4 46   0
EXO1 YOR033C 5--3- exonuclease and flap-endonuclease involved in recombination, double-strand... exonuclease 3 63   0.0034
NTG2 YOL043C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision... endonuclease III DNA base excision repair N-glycosylase 3 23   0
CAC2 YML102W Component of the chromatin assembly complex (with Rlf2p and Msi1p) that assemble... chromatin assembly factor-I (CAF-I) p60 subunit 3 45   0.0064
SNT1 YCR033W Subunit of the Set3C deacetylase complex; putative DNA-binding protein   3 47   0
CDC54 YPR019W Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-...   3 23   0
DSK2 YMR276W Nuclear-enriched ubiquitin-like polyubiquitin-binding protein, required for spin... ubiquitin-like protein 3 22   0.0108
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn1p; pro... ATP-binding cassette (ABC) family 3 18   0
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation as the recruit... Telomere elongation protein 3 30   0.1929
SPT10 YJL127C Putative histone acetylase, required for transcriptional regulation at core prom... transcriptional regulator 3 31   0.0211
UMP1 YBR173C Short-lived chaperone required for correct maturation of the 20S proteasome; deg... 20S proteasome maturation factor 3 24   0.0372
CSE2 YNR010W Component of the Med9/10 module, which is a subcomplex within the RNA polymerase... RNA polymerase II mediator subcomplex component 3 42   0.0002

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