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SONAR Targetspace for CHOLESTAN-3beta,5alpha,6beta-TZ-score WebGraph NB WebGraph
Targetspace hs 152 0
Targetspace hs pval0.00400801603206411
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:30
Sym Orf Description Function No All Z_score hyperg
GYP6 YJL044C GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved... GTPase activating protein (GAP) for Ypt6 6 13   0
GDI1 YER136W GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by r... GDP dissociation inhibitor 6 25   0
YIP3 YNL044W Protein localized to COPII vesicles, proposed to be involved in ER to Golgi tran...   5 43   0
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network; forms heterod...   5 14 -2.9371 0
YIP1 YGR172C Integral membrane protein required for the biogenesis of ER-derived COPII transp...   3 28   0.0657
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5... hydrophilic protein that is peripherally associated with the late Golgi and forms a stable complex with Vps52p and Vps54p 3 18   0.0632
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   3 45   0
YIP4 YGL198W Protein that interacts with Rab GTPases; computational analysis of large-scale p...   3 26   0
MRS6 YOR370C Rab escort protein, forms a complex with the Ras-like small GTPase Ypt1p that is... rab geranylgeranyltransferase regulatory subunit 3 22   0.0025
YOP1 YPR028W Membrane protein that interacts with Yip1p to mediate membrane traffic; overexpr...   3 17   0
YIF1 YNL263C Integral membrane protein required for the fusion of ER-derived COPII transport ...   2 39   0
MDR1 YGR100W Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p, Ypt31... GTPase activating protein (GAP) for Ypt6 2 13   0
CDC50 YCR094W Endosomal protein that regulates cell polarity; similar to Ynr048wp and Lem3p   2 5   0
MSB4 YOL112W GTPase-activating protein of the Ras superfamily that acts primarily on Sec4p, l...   2 11   0
VPS54 YDR027C Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5...   2 22   0
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5...   2 12   0.0322
DRS2 YAL026C Integral membrane Ca(2+)-ATPase involved in aminophospholipid translocation; req... P-type ATPase, potential aminophospholipid translocase 2 29 -6.7823 0.2288
SGM1 YJR134C Protein of unknown function, required for wild-type growth rate on galactose and...   2 8   0.2703
COG6 YNL041C Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   2 31   0
LEM3 YNL323W Membrane protein of the plasma membrane and ER, involved in translocation of pho... membrane glycoprotein 1 14   0
  YNL321W     1 5   0
INO1 YJL153C Inositol 1-phosphate synthase, involved in synthesis of inositol phosphates and ... L-myo-inositol-1-phosphate synthase 1 2   0
MHP1 YJL042W Microtubule-associated protein involved in assembly and stabilization of microtu... microtubule-associated protein (MAP) (putative) 1 10   0.002
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p, involved in nuclear transport GTPase activating protein (GAP) for Gsp1p 1 27   0.0293
TIF34 YMR146C Subunit of the core complex of translation initiation factor 3(eIF3), which is e... translation initiation factor eIF3 p39 subunit 1 52   0
ZUO1 YGR285C Cytosolic ribosome-associated chaperone that acts, together with Ssz1p and the S... zuotin, Z-DNA binding protein (putative) 1 50   0.0841
VPS33 YLR396C ATP-binding protein that is a subunit of the homotypic vacuole fusion and vacuol...   1 35   0.14
VAM6 YDL077C Vacuolar protein that plays a critical role in the tethering steps of vacuolar m...   1 39   0.0499
ACO1 YLR304C Aconitase, required for the tricarboxylic acid (TCA) cycle and also independentl... aconitase 1 28   0
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleot...   1 10 -13.2386 0

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