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SONAR Targetspace for CHOLESTAN-3beta,5alpha,6beta-TZ-score WebGraph NB WebGraph
Targetspace hs 152 0
Targetspace hs pval0.00400801603206411
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   6 12   0.0049
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in v... GTPase activating protein (GAP) 5 67 -1.5552 0
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 4 56   0
  ETG9627     4 5   0
COG1 YGL223C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   3 26   0.0204
EMP70 YLR083C Protein whose 24kDa cleavage product is found in endosome-enriched membrane frac...   3 7   0.2319
USO1 YDL058W Essential protein involved in intracellular protein transport, coiled-coil prote... integrin analogue gene 3 21   0.0221
MAK31 YCR020C-A Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; required...   3 5   0
RER1 YCL001W Protein involved in retention of membrane proteins, including Sec12p, in the ER;...   3 73   0.0019
GAP1 YKR039W General amino acid permease; localization to the plasma membrane is regulated by... general amino acid permease 3 41   0
  YMR010W     3 4   0
SBH1 YER087C-B Beta subunit of the Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p); involv... Sbh2p homolog 3 11   0
ENT4 YLL038C Protein of unknown function, contains an N-terminal epsin-like domain   3 4   0.208
  YEL043W     3 4   0
ENT5 YDR153C Protein containing an N-terminal epsin-like domain involved in clathrin recruitm...   3 8   0.1301
SEC20 YDR498C Membrane glycoprotein v-SNARE involved in retrograde transport from the Golgi to... v-SNARE 3 9   0.1012
NUP2 YLR335W Protein involved in nucleocytoplasmic transport, binds to either the nucleoplasm... nucleoporin 3 27   0
  YDR107C     3 5   0.0447
VPS41 YDR080W Vacuolar membrane protein that is a subunit of the homotypic vacuole fusion and ...   3 14   0.2218
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in tr... v-SNARE 3 14   0.0538
TEF4 YKL081W Translation elongation factor EF-1 gamma translation elongation factor EF-1gamma 3 15   0.223
SFT2 YBL102W Non-essential tetra-spanning membrane protein found mostly in the late Golgi, ca...   3 8   0
OXR1 YPL196W Protein of unknown function required for normal levels of resistance to oxidativ...   3 2   0.0904
NTO1 YPR031W Component of the histone acetyltransferase complex HAT complex component 3 10   0.0001
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane, converts p... phosphatidylserine decarboxylase 3 45   0.0619
MRL1 YPR079W Membrane protein with similarity to mammalian mannose-6-phosphate receptors, pos...   3 3   0.0757
VPS74 YDR372C Non-essential protein of unknown function involved in vacuolar protein sorting; ...   3 47   0.1835
TVP15 YDR100W Integral membrane protein localized to late Golgi vesicles along with the v-SNAR... integral membrane protein 3 3   0
ATG20 YDL113C Protein required for transport of aminopeptidase I (Lap4p) through the cytoplasm... PX domain-containing protein that binds Apg17 and Cvt13, and is required for import of precursor Ape1. 3 6   0
GGA1 YDR358W Golgi-localized protein with homology to gamma-adaptin, interacts with and regul... ARF-binding protein 3 15   0
DSS4 YPR017C Nucleotide release factor functioning in the post-Golgi secretory pathway, requi... GDP dissociation factor for Sec4p 3 14   0.0751
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   3 30   0.1228
YIP1 YGR172C Integral membrane protein required for the biogenesis of ER-derived COPII transp...   3 22   0.0657
INO4 YOL108C Transcription factor required for derepression of inositol-choline-regulated gen... basic helix-loop-helix (bHLH) protein 3 10   0
  YDR266C     3 6   0
  YOR112W     3 6   0.1947
VPS30 YPL120W Protein that forms a membrane-associated complex with Apg14p that is essential f...   3 25   0.1668
  YPL105C     3 2   0
MVP1 YMR004W Protein required for sorting proteins to the vacuole; overproduction of Mvp1p su...   3 16   0
RIM15 YFL033C Glucose-repressible protein kinase involved in signal transduction during cell p... trehalose-associated protein kinase related to S. pombe cek1+ 2 20   0.0145

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