Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   6 12   0.0049
VPS17 YOR132W Subunit of the membrane-associated retromer complex essential for endosome-to-Go...   4 21   0.1825
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane, converts p... phosphatidylserine decarboxylase 3 45   0.0619
SBH1 YER087C-B Beta subunit of the Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p); involv... Sbh2p homolog 3 11   0
INO4 YOL108C Transcription factor required for derepression of inositol-choline-regulated gen... basic helix-loop-helix (bHLH) protein 3 10   0
  YPL105C     3 2   0
SEC20 YDR498C Membrane glycoprotein v-SNARE involved in retrograde transport from the Golgi to... v-SNARE 3 9   0.1012
  YOR112W     3 6   0.1947
RSN1 YMR266W Membrane protein of unknown function; overexpression suppresses NaCl sensitivity...   3 10   0.1388
PKR1 YMR123W Protein of unknown function; overproduction confers resistance to Pichia farinos...   3 32   0
SFT2 YBL102W Non-essential tetra-spanning membrane protein found mostly in the late Golgi, ca...   3 8   0
TEF4 YKL081W Translation elongation factor EF-1 gamma translation elongation factor EF-1gamma 3 15   0.223
GMH1 YKR030W Golgi membrane protein of unknown function, interacts with Gea1p and Gea2p; requ...   3 5   0.0261
ENT4 YLL038C Protein of unknown function, contains an N-terminal epsin-like domain   3 4   0.208
  YMR010W     3 4   0
IMH1 YLR309C Protein involved in vesicular transport, mediates transport between an endosomal...   3 4   0
EMP70 YLR083C Protein whose 24kDa cleavage product is found in endosome-enriched membrane frac...   3 7   0.2319
  YEL043W     3 4   0
  ETG9627     3 5   0
ATG20 YDL113C Protein required for transport of aminopeptidase I (Lap4p) through the cytoplasm... PX domain-containing protein that binds Apg17 and Cvt13, and is required for import of precursor Ape1. 3 6   0
VPS41 YDR080W Vacuolar membrane protein that is a subunit of the homotypic vacuole fusion and ...   3 14   0.2218
OXR1 YPL196W Protein of unknown function required for normal levels of resistance to oxidativ...   3 2   0.0904
TVP15 YDR100W Integral membrane protein localized to late Golgi vesicles along with the v-SNAR... integral membrane protein 3 3   0
YIP1 YGR172C Integral membrane protein required for the biogenesis of ER-derived COPII transp...   3 22   0.0657
MAK31 YCR020C-A Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; required...   3 5   0
  YDR107C     3 5   0.0447
NTO1 YPR031W Component of the histone acetyltransferase complex HAT complex component 3 10   0.0001
  YPR084W     3 4   0.0001
  YDR266C     3 6   0
DSS4 YPR017C Nucleotide release factor functioning in the post-Golgi secretory pathway, requi... GDP dissociation factor for Sec4p 3 14   0.0751
RAV2 YDR202C Subunit of RAVE (Rav1p, Rav2p, Skp1p), a complex that associates with the V1 dom...   3 7   0.0535
MRL1 YPR079W Membrane protein with similarity to mammalian mannose-6-phosphate receptors, pos...   3 3   0.0757
ENT5 YDR153C Protein containing an N-terminal epsin-like domain involved in clathrin recruitm...   3 8   0.1301
SEC28 YIL076W Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein tr... epsilon-COP coatomer subunit 2 19   0
SEC18 YBR080C ATPase required for the release of Sec17p during the -priming- step in homotypic... ATPase|NSF|protein involved in protein transport between ER and Golgi 2 33   0.279
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline... clathrin assembly complex beta adaptin component (putative) 2 10   0
RPL2A YFR031C-A Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and ... ribosomal protein L2A (L5A) (rp8) (YL6) 2 9   0
RIM15 YFL033C Glucose-repressible protein kinase involved in signal transduction during cell p... trehalose-associated protein kinase related to S. pombe cek1+ 2 20   0.0145
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3); functions in... clathrin associated protein complex medium subunit 2 15   0
TLG1 YDR468C Essential t-SNARE that forms a complex with Tlg2p and Vti1p and mediates fusion ... tSNARE that affects a late Golgi compartment 2 6   0.0438

Service provided by the Mike Tyers Laboratory