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SONAR Targetspace for METHYL DEOXYCHOLATEZ-score WebGraph NB WebGraph
Targetspace hs 232 91
Targetspace hs pval0.043750.26196473551637
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:39
Sym Orf Description Function No All Z_score hyperg
PCL2 YDL127W G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to... G1 cyclin 22 19   0
PTP2 YOR208W Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 19 28   0
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   18 71 0.4517 0.0077
PCL1 YNL289W Pho85 cyclin of the Pcl1,2-like subfamily, involved in entry into the mitotic ce... G1 cyclin|associates with PHO85 17 25   0.0025
MID2 YLR332W O-glycosylated plasma membrane protein that acts as a sensor for cell wall integ...   16 46   0.0525
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase, component of the cAMP-dependent prot... high affinity cAMP phosphodiesterase 16 62   0.023
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p), a membrane-associated co...   14 24   0
CNB1 YKL190W Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulate... calcineurin regulatory B subunit|type 2B protein phosphatase 14 81 -0.6591 0
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   13 54   0
HKR1 YDR420W Serine/threonine rich cell surface protein that contains an EF hand motif; invol... contains EF hand motif|type I transmembrane protein 13 25   0
YPK2 YMR104C Protein kinase with similarityto serine/threonine protein kinase Ypk1p; function... protein kinase 12 12   0
LAS21 YJL062W Integral plasma membrane protein involved in the synthesis of the glycosylphosph... major facilitator superfamily (putative)|membrane protein (putative) 12 74   0
CCW12 YLR110C Cell wall protein, mutants are defective in mating and agglutination, expression... cell wall mannoprotein 12 115   0.0001
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely... rho GTPase 12 8   0.0002
PKH2 YOL100W Serine/threonine protein kinase involved in sphingolipid-mediated signaling path...   11 19   0
CHS7 YHR142W Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p...   11 45 -5.7931 0
SBE2 YDR351W Protein involved in the transport of cell wall components from the Golgi to the ...   11 7   0.1345
POG1 YIL122W Putative transcriptional activator that promotes recovery from pheromone induced... transcription factor (putative) 10 7   0
PKH1 YDR490C Serine/threonine protein kinase involved in sphingolipid-mediated signaling path...   10 22   0
MYO2 YOR326W One of two type V myosins, involved in polarized distribution of mitochondria; r... class V myosin 10 104   0
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway involved in m...   10 49   0.011
SWF1 YDR126W Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on a...   10 48   0
MTL1 YGR023W Protein with both structural and functional similarity to Mid2p, which is a plas... acts in concert with Mid2p to transduce cell wall stress signals 10 11   0
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, requ... scaffold protein 10 41 -2.2091 NAN
  YKL161C     10 5   0.1116
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of the ER membrane, catalyzes th... dolichol phosphate mannose synthase 9 8   0
MOB1 YIL106W Component of the mitotic exit network; associates with and is required for the a...   9 22   0
YPK1 YKL126W Serine/threonine protein kinase required for receptor-mediated endocytosis; invo... 76.5 kDa serine/threonine protein kinase|similarity to protein kinase C, is 90% identical to Ypk2p 9 40   0
OPI1 YHL020C Transcriptional regulator of a variety of genes; phosphorylation by protein kina...   9 22   0
MKK1 YOR231W Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... MAP kinase kinase (MEK) 9 26 -5.3082 0.1292
CHS6 YJL099W Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p...   8 54   NAN
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member involved in genome ... high mobility group (HMG) family 8 60   0.0052
KAR1 YNL188W Essential protein involved in karyogamy during mating and in spindle pole body d...   8 16   0.0215
CDC34 YDR054C Ubiquitin-conjugating enzyme or E2; together with Skp1p, Rbx1p, Cdc53p, and an F... ubiquitin-conjugating enzyme 8 58   0.0001
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that functions to modulate Rhop1 activi...   8 26   0.0819
  YKL037W     7 12   0.0347
SGD1 YLR336C Essential nuclear protein with a possible role in the osmoregulatory glycerol re...   6 4   0
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways... MAP kinase 6 26   0
CDC53 YDL132W Cullin, structural protein of SCF complexes (which also contain Skp1p, Cdc34p, a...   6 24   0

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