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SONAR Targetspace for AVOCADENEZ-score WebGraph NB WebGraph
Targetspace hs 72 0
Targetspace hs pval0.789285714285711
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding and autopha... vesicle coat component 8 14   0
SEC13 YLR208W Component of both the Nup84 nuclear pore sub-complex and of the COPII complex (S... nuclear pore complex subunit|protein involved in release of transport vesicles from the ER 7 25   0
SEC12 YNR026C Guanine nucleotide exchange factor (GEF); glycosylated integral membrane protein... guanine nucleotide exchange factor for Sar1p 7 27   0
UFE1 YOR075W t-SNARE required for ER membrane fusion and vesicular traffic, integral membrane... t-SNARE (ER) 4 18   0.0007
SIL1 YOL031C Nucleotide exchange factor for the endoplasmic reticulum (ER) lumenal Hsp70 chap... Nucleotide exchange factor 4 52   0
  YBR138C     4 1   0
SEC31 YDL195W Essential phosphoprotein component (p150) of the COPII coat of secretory pathway... COPII coat of secretory pathway vesicles component (p150) 4 9   0
DER1 YBR201W Endoplasmic reticulum membrane protein, required for ER-associated protein degra...   4 20   0.1431
ERD2 YBL040C Integral membrane protein that binds to the HDEL motif in proteins destined for ... HDEL receptor 4 8   0.0067
SAR1 YPL218W GTPase, GTP-binding protein of the ARF family, component of COPII coat of vesicl... ARF family|GTP-binding protein 4 14   0
KAR2 YJL034W ATPase involved in protein import into the ER, also acts as a chaperone to media... HSP70 family|mammalian BiP (GRP78 or HSPA5) homolog 4 20   0
  YKL206C     4 3   0
SEC6 YIL068C Essential 88kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec1... exocyst complex component 4 43   0.1797
COS8 YHL048W Nuclear membrane protein, member of the DUP380 subfamily of conserved, often sub...   4 4   0
MKC7 YDR144C GPI-anchored aspartyl protease (yapsin) involved in protein processing; shares f... aspartyl protease|related to Yap3p|yapsin 2 4 12   0
ERV29 YGR284C Protein localized to COPII-coated vesicles, involved in vesicle formation and in... ER-Golgi transport vesicle protein 4 24   0.0185
SEC24 YIL109C Component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat; ... vesicle coat component 4 11   0.1347
ARV1 YLR242C Protein required for normal intracellular sterol distribution and for sphingolip... Protein involved in sterol distribution 3 20   0.0988
QRI8 YMR022W Ubiquitin conjugating enzyme, involved in the ER-associated protein degradation ... ubiquitin-conjugating enzyme 3 69   0.0142
SEC17 YBL050W Peripheral membrane protein required for vesicular transport between ER and Golg...   3 11   0
ERJ5 YFR041C Endoplasmic reticulum protein that may function as a cochaperone, as suggested b...   3 8   0
HRD1 YOL013C Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradati...   3 61   0.1744
HEM1 YDR232W 5-aminolevulinate synthase, catalyzes the first step in the heme biosynthetic pa... 5-aminolevulinate synthase 3 10   0
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase, associates with transcriptionally active...   2 60   0.2442
ZAP1 YJL056C Zinc-regulated transcription factor, binds to zinc-responsive promoter elements ...   2 30   0
HXT8 YJL214W Protein of unknown function with similarity to hexose transporter family members... hexose permease 2 13   0
TIR3 YIL011W Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins... cell wall mannoprotein 2 3   0
DNL4 YOR005C DNA ligase required for nonhomologous end-joining (NHEJ), forms stable heterodim... ATP dependent DNA ligase 2 15   0.0596
NTG2 YOL043C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision... endonuclease III DNA base excision repair N-glycosylase 2 23   0.0003
RIM11 YMR139W Protein kinase required for signal transduction during entry into meiosis; promo...   2 10   0.0844
UBX4 YMR067C UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48...   2 37   0.004
HSF1 YGL073W Trimeric heat shock transcription factor, activates multiple genes in response t... heat shock transcription factor 2 32   0.0022
ERG6 YML008C Delta(24)-sterol C-methyltransferase, converts zymosterol to fecosterol in the e...   2 47   0
REV1 YOR346W Deoxycytidyl transferase, forms a complex with the subunits of DNA polymerase ze... deoxycytidyl transferase 2 32   0.0059
DIE2 YGR227W Dolichyl-phosphoglucose-dependent glucosyltransferase of the ER, functions in th... glucosyltransferase 2 48   0.2163
CYS3 YAL012W Cystathionine gamma-lyase, catalyzes one of the two reactions involved in the tr... cystathionine gamma-lyase 2 61   0
TRM2 YKR056W tRNA methyltransferase, 5-methylates the uridine residue at position 54 of tRNAs... tRNA methyltransferase 2 6   0.1154
YBP2 YGL060W Protein with a role in resistance to oxidative stress; has similarity to Ybp1p, ...   2 9   0.2417
NTG1 YAL015C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision... DNA glycosylase 2 23   0.0755
BUL1 YMR275C Ubiquitin-binding component of the Rsp5p E3-ubiquitin ligase complex, functional...   2 25   0.0055

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