Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:35
Sym Orf Description Function No All Z_score hyperg
GSH1 YJL101C Gamma glutamylcysteine synthetase, catalyzes the first step in the gamma-glutamy... gamma-glutamylcysteine synthetase 11 150   0
SIW14 YNL032W Tyrosine phosphatase that plays a role in actin filament organization and endocy... tyrosine phosphatase 11 113   0
RPI1 YIL119C Putative transcriptional regulator; overexpression suppresses the heat shock sen... ras inhibitor 11 46   0.0003
LST4 YKL176C Protein possibly involved in a post-Golgi secretory pathway; required for the tr...   11 128   0
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation...   10 31   0.1342
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 10 95   0
CNA1 YLR433C Calcineurin A; one isoform (the other is CMP2) of the catalytic subunit of calci... calcineurin subunit A 9 49   0.0009
HPT1 YDR399W Dimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation ... hypoxanthine guanine phosphoribosyltransferase 8 119   0
CMK2 YOL016C Calmodulin-dependent protein kinase; may play a role in stress response, many CA... calmodulin-dependent protein kinase 8 90   0
MEH1 YKR007W Component of the EGO complex, which is involved in the regulation of microautoph...   8 131   0
ATG21 YPL100W Phosphatidylinositol 3,5-bisphosphate-binding protein required for maturation of...   8 76   0
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for... MAP kinase 8 36   0
MSG5 YNL053W Dual-specificity protein phosphatase required for maintenance of a low level of ... protein tyrosine phosphatase 7 60   0
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase; identified as a high-copy number suppre... type 2C protein phosphatase 7 74   0.123
MKK1 YOR231W Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... MAP kinase kinase (MEK) 7 96 -1.9218 0.0768
  YPL077C     7 26   0.0005
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase), catalyzes the rapid exchange of o... inorganic pyrophosphatase 7 70   0
PTC3 YBL056W Type 2C protein phosphatase; dephosphorylates Hog1p (see also Ptc2p) to limit ma... protein phosphatase type 2C 7 41   0
RLM1 YPL089C MADS-box transcription factor, component of the protein kinase C-mediated MAP ki...   7 47   0.1639
FOL2 YGR267C GTP-cyclohydrolase I, catalyzes the first step in the folic acid biosynthetic pa... GTP-cyclohydrolase I 6 26   0
SKO1 YNL167C Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family that for...   6 38   0
WSC2 YNL283C Partially redundant sensor-transducer of the stress-activated PKC1-MPK1 signalin... contains novel cysteine motif|integral membrane protein (putative)|similar to SLG1 (WSC1), WSC3 and WSC4 6 39   0
MCM1 YMR043W Transcription factor involved in cell-type-specific transcription and pheromone ... contains the 56 amino-acid MADS (MCM1, AG, DEFAm SRF)-box motif within its DNA binding domain, plays a central role in the formation of both repressor and activator complexes|transcription factor 6 39   0
PDR12 YPL058C Plasma membrane weak-acid-inducible ATP-binding cassette (ABC) transporter, requ... multidrug resistance transporter 6 70   0
VHS3 YOR054C Functionally redundant (see also SIS2) inhibitory subunit of Ppz1p, a PP1c-relat...   6 68   0
GAL7 YBR018C Galactose-1-phosphate uridyl transferase, synthesizes glucose-1-phosphate and UD... galactose-1-phosphate uridyl transferase 6 28   0
OCA1 YNL099C Putative protein tyrosine phosphatase, required for cell cycle arrest in respons...   6 107   0
  YDR049W     6 147   0
PRE3 YJL001W 20S proteasome beta-type subunit, responsible for cleavage after acidic residues... 20S proteasome subunit 5 60   0
MPM1 YJL066C Mitochondrial membrane protein of unknown function, contains no hydrophobic stre...   5 15   0
SDP1 YIL113W Stress-inducible dual-specificity MAP kinase phosphatase, negatively regulates S...   5 13   0
RPC10 YHR143W-A RNA polymerase subunit, found in RNA polymerase complexes I, II, and III RNA polymerase II subunit 5 51   0
BOR1 YNL275W Plasma membrane protein that binds HCO3-, I-, Br-, NO3- and Cl- ; putative boron... boron efflux transporter 5 18   0
NCP1 YHR042W NADP-cytochrome P450 reductase; involved in ergosterol biosynthesis; associated ... NADP-cytochrome P450 reductase 5 31   0
PRS3 YHL011C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, his... ribose-phosphate pyrophosphokinase 5 37   0

Service provided by the Mike Tyers Laboratory