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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:38
Sym Orf Description Function No All Z_score hyperg
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 21 145 -18.4600 NAN
PTC1 YDL006W Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by ...   14 64   0.1178
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alt... 1,3-beta-D-glucan synthase 13 126 -12.5151 0
ROT2 YBR229C Glucosidase II catalytic subunit required for normal cell wall synthesis; mutati... glucosidase II 12 92 -0.5413 0.1064
SIW14 YNL032W Tyrosine phosphatase that plays a role in actin filament organization and endocy... tyrosine phosphatase 12 16   0
RIM101 YHL027W Transcriptional repressor involved in the response to pH; required for alkaline ...   12 65   0.1269
KRE11 YGR166W Protein involved in biosynthesis of cell wall beta-glucans; subunit of the TRAPP...   12 62   0
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   11 54   0
OPI3 YJR073C Phospholipid methyltransferase (methylene-fatty-acyl-phospholipid synthase), cat... unsaturated phospholipid N-methyltransferase 11 126   NAN
CCW12 YLR110C Cell wall protein, mutants are defective in mating and agglutination, expression... cell wall mannoprotein 11 115   0.0004
FPS1 YLL043W Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) fa... glycerol channel protein 11 28   0.0028
RVS167 YDR388W Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) involved in reg... cytoskeletal protein (putative) 10 108 -9.6581 0
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation...   10 10   0.1342
RPI1 YIL119C Putative transcriptional regulator; overexpression suppresses the heat shock sen... ras inhibitor 10 9   0.0011
CNB1 YKL190W Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulate... calcineurin regulatory B subunit|type 2B protein phosphatase 10 81 -39.8870 0
  YKL037W     10 12   0.0015
  YKL161C     10 5   0.1116
MID2 YLR332W O-glycosylated plasma membrane protein that acts as a sensor for cell wall integ...   9 46   0.0007
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation...   9 31 -35.7790 0.1429
KAR1 YNL188W Essential protein involved in karyogamy during mating and in spindle pole body d...   9 16   0.0083
MYO2 YOR326W One of two type V myosins, involved in polarized distribution of mitochondria; r... class V myosin 9 104   0
CHS5 YLR330W Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p...   8 107 -43.9367 0
SYS1 YJL004C Integral membrane protein of the Golgi required for targeting of the Arf-like GT...   8 41   0
IRA2 YOL081W GTPase-activating protein that negatively regulates RAS by converting it from th... GTPase activating protein|highly homologous to Ira1p|neurofibromin homolog 8 32   0
MKK1 YOR231W Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... MAP kinase kinase (MEK) 8 26 -1.9218 0.1064
ROT1 YMR200W Protein that may be involved in cell wall function; mutations in rot1 cause cell... membrane protein (putative) 8 27   0
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that functions to modulate Rhop1 activi...   8 26   0.0819
KEL1 YHR158C Protein required for proper cell fusion and cell morphology; functions in a comp...   7 24   0
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase; identified as a high-copy number suppre... type 2C protein phosphatase 7 4   0.123
CDC15 YAR019C Protein kinase of the Mitotic Exit Network that is localized to the spindle pole... protein kinase domain 7 66   0.0377
SEC66 YBR171W Non-essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with... glycoprotein complexed with Sec62p and Sec63p in the Sec63 complex, an integral endoplasmic reticulum membrane protein complex required for translocation of presecretory proteins 7 109 -0.1558 NAN
CHS6 YJL099W Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p...   7 54   NAN
MOB1 YIL106W Component of the mitotic exit network; associates with and is required for the a...   7 22   0
PTC3 YBL056W Type 2C protein phosphatase; dephosphorylates Hog1p (see also Ptc2p) to limit ma... protein phosphatase type 2C 7 11   0
GAS1 YMR307W Beta-1.3-glucanosyltransferase, required for cell wall assembly; localizes to th... cell surface glycoprotein 115-120 kDa 7 111 -7.7605 0
ARL3 YPL051W GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to...   6 42 -29.0224 0
PKH1 YDR490C Serine/threonine protein kinase involved in sphingolipid-mediated signaling path...   6 22   0
SET3 YKR029C Defining member of the SET3 histone deacetylase complex which is a meiosis-speci...   6 90   0

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