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SONAR Targetspace for 5,7-DIHYDROXYISOFLAVONEZ-score WebGraph NB WebGraph
Targetspace hs 284 280
Targetspace hs pval0.143835616438360.070512820512821
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:39
Sym Orf Description Function No All Z_score hyperg
DCR2 YLR361C Putative phosphoesterase that functions as a dosage-dependent positive regulator...   9 19   0
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding and autopha... vesicle coat component 8 14   0
SEC23 YPR181C GTPase-activating protein; component of the Sec23p-Sec24p heterodimeric complex ... GTPase activating protein (GAP) 8 30   0
SEC13 YLR208W Component of both the Nup84 nuclear pore sub-complex and of the COPII complex (S... nuclear pore complex subunit|protein involved in release of transport vesicles from the ER 7 25   0
SEC12 YNR026C Guanine nucleotide exchange factor (GEF); glycosylated integral membrane protein... guanine nucleotide exchange factor for Sar1p 7 27   0
KAR9 YPL269W Karyogamy protein required for correct positioning of the mitotic spindle and fo...   7 82   0
SIL1 YOL031C Nucleotide exchange factor for the endoplasmic reticulum (ER) lumenal Hsp70 chap... Nucleotide exchange factor 6 52   0
QRI8 YMR022W Ubiquitin conjugating enzyme, involved in the ER-associated protein degradation ... ubiquitin-conjugating enzyme 6 69   0.1014
SEC27 YGL137W Essential beta--coat protein of the COPI coatomer, involved in ER-to-Golgi and G... yeast coatomer beta--subunit 6 14   0
GET3 YDL100C ATPase, subunit of the GET complex; required for the retrieval of HDEL proteins ...   6 110   0.0029
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   6 30   0.1691
HEM1 YDR232W 5-aminolevulinate synthase, catalyzes the first step in the heme biosynthetic pa... 5-aminolevulinate synthase 6 10   0
SSD1 YDR293C Protein with a role in maintenance of cellular integrity, interacts with compone...   5 72   0.1435
HRD1 YOL013C Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradati...   5 61   0.0283
BBC1 YJL020C Protein possibly involved in assembly of actin patches; interacts with an actin ...   5 28   0.18
EST2 YLR318W Reverse transcriptase subunit of the telomerase holoenzyme, essential for telome... telomerase reverse transcriptase 5 39   0.1494
URM1 YIL008W Ubiquitin-like protein with only weak sequence similarity to ubiquitin; depends ... ubiquitin-like protein 5 56   0
PIK1 YNL267W Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosp... phosphatidylinositol 4-kinase 5 108   0.0004
UBA4 YHR111W Protein that activates Urm1p before its conjugation to proteins (urmylation); on...   5 43   0
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in v... GTPase activating protein (GAP) 5 67 0.4138 0
RET3 YPL010W Zeta subunit of the coatomer complex (COPI), which coats Golgi-derived transport... vesicle coat component 5 2   0
SEC6 YIL068C Essential 88kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec1... exocyst complex component 4 43   0.1797
ADE3 YGR204W Cytoplasmic trifunctional enzyme C1-tetrahydrofolate synthase, involved in singl... C1-tetrahydrofolate synthase 4 10   0
ZAP1 YJL056C Zinc-regulated transcription factor, binds to zinc-responsive promoter elements ...   4 30   0
RER1 YCL001W Protein involved in retention of membrane proteins, including Sec12p, in the ER;...   4 73   0.0061
  YIL039W     4 65   0
ERD2 YBL040C Integral membrane protein that binds to the HDEL motif in proteins destined for ... HDEL receptor 4 8   0.0067
COS8 YHL048W Nuclear membrane protein, member of the DUP380 subfamily of conserved, often sub...   4 4   0
ERV29 YGR284C Protein localized to COPII-coated vesicles, involved in vesicle formation and in... ER-Golgi transport vesicle protein 4 24   0.0185
CDC50 YCR094W Endosomal protein that regulates cell polarity; similar to Ynr048wp and Lem3p   4 41   0
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis; interacts and functio... transcription factor 4 76   0
BUD6 YLR319C Actin- and formin-interacting protein, involved in actin cable nucleation and po...   4 36   0.0027
KAR2 YJL034W ATPase involved in protein import into the ER, also acts as a chaperone to media... HSP70 family|mammalian BiP (GRP78 or HSPA5) homolog 4 20   0
MKC7 YDR144C GPI-anchored aspartyl protease (yapsin) involved in protein processing; shares f... aspartyl protease|related to Yap3p|yapsin 2 4 12   0
GSG1 YDR108W Subunit of TRAPP (transport protein particle), a multi-subunit complex involved ...   4 97   0
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which cataly... NAD-dependent isocitrate dehydrogenase 4 15 -4.7476 0.0489
SEC24 YIL109C Component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat; ... vesicle coat component 4 11   0.1347
SYS1 YJL004C Integral membrane protein of the Golgi required for targeting of the Arf-like GT...   4 41   0
  YKL206C     4 3   0

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