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SONAR Targetspace for LANOSTEROLZ-score WebGraph NB WebGraph
Targetspace hs 222 0
Targetspace hs pval0.883458646616541
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   2 12   0.2715
MAF1 YDR005C Negative regulator of RNA polymerase III; component of several signaling pathway...   2 50   0.1925
SEC18 YBR080C ATPase required for the release of Sec17p during the -priming- step in homotypic... ATPase|NSF|protein involved in protein transport between ER and Golgi 2 33   0.279
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 2 56   0
ERV14 YGL054C Protein localized to COPII-coated vesicles, involved in vesicle formation and in... 14 kDa protein found on ER-derived vesicles 1 76   0
ZRT1 YGL255W High-affinity zinc transporter of the plasma membrane, responsible for the major...   1 7   0.1914
RPL2A YFR031C-A Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and ... ribosomal protein L2A (L5A) (rp8) (YL6) 1 9   0
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway, along with Nam7p an...   1 20   0.0031
BST1 YFL025C GPI inositol deacylase of the ER that negatively regulates COPII vesicle formati...   1 41   0
RIM15 YFL033C Glucose-repressible protein kinase involved in signal transduction during cell p... trehalose-associated protein kinase related to S. pombe cek1+ 1 20   0.0036
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline... clathrin assembly complex beta adaptin component (putative) 1 10   0
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   1 23   0
GEF1 YJR040W Chloride channel localized to late- or post-Golgi vesicles, involved in iron met... transport protein involved in intracellular iron metabolism (putative) 1 10   0
TEF4 YKL081W Translation elongation factor EF-1 gamma translation elongation factor EF-1gamma 1 15   0.0931
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   1 30   0.0229
  YJL123C     1 30   0.3804
RAD4 YER162C Protein that recognizes and binds damaged DNA (with Rad23p) during nucleotide ex...   1 17   0.3771
  YIL039W     1 65   0
SEC28 YIL076W Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein tr... epsilon-COP coatomer subunit 1 19   0
SBH1 YER087C-B Beta subunit of the Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p); involv... Sbh2p homolog 1 11   0
  ETG51154     1 1   0
MAK31 YCR020C-A Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; required...   1 5   0
USO1 YDL058W Essential protein involved in intracellular protein transport, coiled-coil prote... integrin analogue gene 1 21   0.3447
RER1 YCL001W Protein involved in retention of membrane proteins, including Sec12p, in the ER;...   1 73   0.0001
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3); functions in... clathrin associated protein complex medium subunit 1 15   0
RPP0 YLR340W Conserved ribosomal protein P0 similar to rat P0, human P0, and E. coli L10e; sh... ribosomal protein P0 (A0) (L10E) 1 1   0
MOT2 YER068W Component of the CCR4-NOT transcription regulatory complex, which represses tran... zinc finger protein (putative) 1 72   0.0864
SFT2 YBL102W Non-essential tetra-spanning membrane protein found mostly in the late Golgi, ca...   1 8   0
GET3 YDL100C ATPase, subunit of the GET complex; required for the retrieval of HDEL proteins ...   1 110   0
RPL35A YDL191W Protein component of the large (60S) ribosomal subunit, identical to Rpl35Bp and... ribosomal protein L35A 1 13   0.1837
SEC20 YDR498C Membrane glycoprotein v-SNARE involved in retrograde transport from the Golgi to... v-SNARE 1 9   0.3677
  YEL043W     1 4   0
VMA8 YEL051W Subunit D of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-... V1 catalytic sector D subunit|vacuolar H-ATPase 1 7   0.3338
TLG1 YDR468C Essential t-SNARE that forms a complex with Tlg2p and Vti1p and mediates fusion ... tSNARE that affects a late Golgi compartment 1 6   0.2526
  YDR266C     1 6   0.0312
  YDR107C     1 5   0.0045
ENT5 YDR153C Protein containing an N-terminal epsin-like domain involved in clathrin recruitm...   1 8   0.0256
SLY1 YDR189W Hydrophilic protein involved in vesicle trafficking between the ER and Golgi; SM... t-SNARE-interacting protein that functions in ER-to-Golgi traffic 1 38   0.0446
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in tr... v-SNARE 1 14   0.0058
IRS4 YKR019C Protein involved in regulation of phosphatidylinositol 4,5-bisphosphate concentr...   1 10   0.0945

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