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SONAR Targetspace for LANOSTEROLZ-score WebGraph NB WebGraph
Targetspace hs 222 0
Targetspace hs pval0.883458646616541
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:37
Sym Orf Description Function No All Z_score hyperg
NOP2 YNL061W Probable RNA m(5)C methyltransferase, essential for processing and maturation of... 90 kDa protein homologous to a human proliferation-associated nucleolar protein, p120 3 145   0
KRR1 YCL059C Essential nucleolar protein required for the synthesis of 18S rRNA and for the a...   3 140   0
GDI1 YER136W GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by r... GDP dissociation inhibitor 2 37   0
RAD4 YER162C Protein that recognizes and binds damaged DNA (with Rad23p) during nucleotide ex...   2 147   0.2197
  YDL133W     2 126   0
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric arginine dimethylating methyltransfer... arginine methyltransferase|mono- and asymmetrically dimethylating enzyme 2 63   0.1033
MUD1 YBR119W U1 snRNP A protein, homolog of human U1-A; involved in nuclear mRNA splicing U1 snRNP A protein 2 109   0.1551
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 2 91   0
QCR6 YFR033C Subunit 6 of the ubiquinol cytochrome-c reductase complex, which is a component ... ubiquinol cytochrome C oxidoreductase subunit 6 (17 kDa) 2 60   0
GYP6 YJL044C GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved... GTPase activating protein (GAP) for Ypt6 2 107   0.0684
SDS22 YKL193C Conserved nuclear regulatory subunit of Glc7p type 1 protein serine-threonine ph... Glc7p regulatory subunit 2 95   0
SYG1 YIL047C Plasma membrane protein of unknown function; truncation and overexpression suppr... plasma membrane protein 2 46   0
YIP1 YGR172C Integral membrane protein required for the biogenesis of ER-derived COPII transp...   2 48   0.1947
  YGR071C     2 54   0.1316
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   2 94   0
RPC53 YDL150W RNA polymerase III subunit C53 RNA polymerase III subunit 2 82   0
ESC8 YOL017W Protein involved in telomeric and mating-type locus silencing, interacts with Si...   2 51   0
SAN1 YDR143C Ubiquitin-protein ligase, involved in the proteasome-dependent degradation of ab...   2 86   0.1028
USO1 YDL058W Essential protein involved in intracellular protein transport, coiled-coil prote... integrin analogue gene 2 79   0.1078
OYE3 YPL171C Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), ho... NADPH dehydrogenase 2 47   0
RRP8 YDR083W Nucleolar protein involved in rRNA processing, pre-rRNA cleavage at site A2; als... nucleolar protein required for efficient processing of pre-rRNA at site A2; methyltransferase homolog 2 121   0.0029
LCP5 YER127W Essential protein involved in maturation of 18S rRNA; depletion leads to inhibit...   2 76   0
URB1 YKL014C Nucleolar protein required for the normal accumulation of 25S and 5.8S rRNAs, as...   2 97   0
NOC2 YOR206W Protein that forms a nucleolar complex with Mak21p that binds to 90S and 66S pre...   2 120   0
YTM1 YOR272W Constituent of 66S pre-ribosomal particles, required for maturation of the large... microtubule-associated protein 2 94   0
NMD5 YJR132W Karyopherin, a carrier protein involved in nuclear import of proteins; importin ... Upf1p interacting protein|importin beta homolog Kap119p 2 75   0
RPL24B YGR148C Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to ... ribosomal protein L24B (rp29) (YL21) (L30B) 2 40   0
RSA3 YLR221C Protein with a likely role in ribosomal maturation, required for accumulation of...   2 82   0.0051
CCA1 YER168C ATP (CTP):tRNA-specific tRNA nucleotidyltransferase; different forms targeted to... tRNA nucleotidyltransferase (tRNA CCA-pyrophosphorylase) 2 16   0
TEC1 YBR083W Transcription factor required for full Ty1 epxression, Ty1-mediated gene activat... TEA/ATTS DNA-binding domain family transcription factor 2 72   0.2701
UGA4 YDL210W Permease that serves as a gamma-aminobutyrate (GABA) transport protein involved ... GABA-specific transport protein 1 24   0
RPL7B YPL198W Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl7... ribosomal protein L7B (L6B) (rp11) (YL8) 1 105   0
MSL5 YLR116W Component of the commitment complex, which defines the first step in the splicin...   1 31   0
RPL1A YPL220W N-terminally acetylated protein component of the large (60S) ribosomal subunit, ... ribosomal protein L1A, forms part of the 60S ribosomal subunit 1 98   0
SPB1 YCL054W AdoMet-dependent methyltransferase involved in rRNA processing and 60S ribosomal... AdoMet-dependent rRNA methyltransferase 1 38   0
NRG2 YBR066C Transcriptional repressor that mediates glucose repression and negatively regula... NRG1 homolog 1 24   0
PRP6 YBR055C Splicing factor, component of the U4/U6-U5 snRNP complex RNA splicing factor 1 145   0

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