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SONAR Targetspace for ONONETINZ-score WebGraph NB WebGraph
Targetspace hs 142 93
Targetspace hs pval0.162412993039440.25879396984925
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:39
Sym Orf Description Function No All Z_score hyperg
SYS1 YJL004C Integral membrane protein of the Golgi required for targeting of the Arf-like GT...   11 41   0
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in v... GTPase activating protein (GAP) 11 67 -2.1094 0
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   10 30   0.0244
ARL3 YPL051W GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to...   10 42 -5.4227 0
TLG2 YOL018C Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fus... tSNARE that affects a late Golgi compartment 10 128   0
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic; regulates potassiu... ADP-ribosylation factor-like protein 1 9 141   0
VPS17 YOR132W Subunit of the membrane-associated retromer complex essential for endosome-to-Go...   8 21   0.0076
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 8 56   0.0034
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   8 12   0.0002
PKR1 YMR123W Protein of unknown function; overproduction confers resistance to Pichia farinos...   7 32   0
SKY1 YMR216C SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabo...   7 97   0.0005
SWA2 YDR320C Auxilin-like protein involved in vesicular transport; clathrin-binding protein r... auxilin-like protein 6 24   0
RER1 YCL001W Protein involved in retention of membrane proteins, including Sec12p, in the ER;...   6 73   0.0322
CNB1 YKL190W Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulate... calcineurin regulatory B subunit|type 2B protein phosphatase 6 81 -1.9289 0
MVP1 YMR004W Protein required for sorting proteins to the vacuole; overproduction of Mvp1p su...   6 16   0
DCR2 YLR361C Putative phosphoesterase that functions as a dosage-dependent positive regulator...   6 19   0
CBK1 YNL161W Serine/threonine protein kinase that regulates cell morphogenesis pathways; invo... serine/threonine protein kinase 6 41   0.0001
CDC50 YCR094W Endosomal protein that regulates cell polarity; similar to Ynr048wp and Lem3p   6 41   0
  YPR084W     5 4   0.0009
  ETG9627     5 5   0
PEP8 YJL053W Vacuolar protein sorting protein that forms part of the multimeric membrane-asso... vacuolar protein similar to mouse gene H<beta>58 5 27   0
OPI3 YJR073C Phospholipid methyltransferase (methylene-fatty-acyl-phospholipid synthase), cat... unsaturated phospholipid N-methyltransferase 5 126   0
SUR1 YPL057C Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synth... integral membrane protein 5 40   0.0055
INP53 YOR109W Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein w... inositol polyphosphate 5-phosphatase 5 77   0.0123
VAM10 YOR068C Protein involved in vacuole morphogenesis; acts at an early step of homotypic va... Required for normal tethering of vacuoles prior to fusion. 5 18   0.1199
SEC28 YIL076W Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein tr... epsilon-COP coatomer subunit 5 19   0
PIK1 YNL267W Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosp... phosphatidylinositol 4-kinase 5 108   0.0004
SEC27 YGL137W Essential beta--coat protein of the COPI coatomer, involved in ER-to-Golgi and G... yeast coatomer beta--subunit 5 14   0
TFP1 YDL185W Vacuolar ATPase V1 domain subunit A containing the catalytic nucleotide binding ... protein with three regions (ABC) that are spliced to yield the extein AC and the intein B; AC is a 69K vacuolar (H+)-ATPase, and B is a 50K site-specfic endonuclease named VDE (PI-SceI) that is homologous to HO. Cleavage is meiosis-specific and induces ge|site-specific endonuclease VDE (PI-SceI)|vacuolar ATPase V1 domain subunit A (69 kDa) 5 65 -0.7052 0.0393
GMH1 YKR030W Golgi membrane protein of unknown function, interacts with Gea1p and Gea2p; requ...   5 5   0.0933
GSG1 YDR108W Subunit of TRAPP (transport protein particle), a multi-subunit complex involved ...   5 97   0
COG7 YGL005C Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   5 20   0
VPS5 YOR069W Nexin-1 homolog required for localizing membrane proteins from a prevacuolar/lat... simialr to sorting nexin I 5 26 -1.9082 0.0022
COG5 YNL051W Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   5 89   0
COG6 YNL041C Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   5 57   0
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   5 23   0
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5... function unknown 5 110   0.0639
VPS30 YPL120W Protein that forms a membrane-associated complex with Apg14p that is essential f...   5 25   0.1879
MAK3 YPR051W Catalytic subunit of N-terminal acetyltransferase of the NatC type; required for... N-acetyltransferase 5 20   0.0005

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