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SONAR Targetspace for IRIGINOL HEXAACEATATEZ-score WebGraph NB WebGraph
Targetspace hs 154 334
Targetspace hs pval0.0525210084033610.26835443037975
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:37
Sym Orf Description Function No All Z_score hyperg
QRI8 YMR022W Ubiquitin conjugating enzyme, involved in the ER-associated protein degradation ... ubiquitin-conjugating enzyme 8 69   0.1506
SEC12 YNR026C Guanine nucleotide exchange factor (GEF); glycosylated integral membrane protein... guanine nucleotide exchange factor for Sar1p 8 27   0
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding and autopha... vesicle coat component 8 14   0
SEC13 YLR208W Component of both the Nup84 nuclear pore sub-complex and of the COPII complex (S... nuclear pore complex subunit|protein involved in release of transport vesicles from the ER 8 25   0
MUS81 YDR386W Helix-hairpin-helix protein, involved in DNA repair and replication fork stabili...   7 72   0
SIL1 YOL031C Nucleotide exchange factor for the endoplasmic reticulum (ER) lumenal Hsp70 chap... Nucleotide exchange factor 6 52   0
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation via three independen... MAP kinase 6 81 2.9994 0.0099
ERG6 YML008C Delta(24)-sterol C-methyltransferase, converts zymosterol to fecosterol in the e...   5 47   0.0017
SIN4 YNL236W Subunit of the Mediator complex; interacts with the RNA polymerase II holoenzyme... RNA polymerase II holoenzyme/mediator subunit 5 59   0.0995
TUB3 YML124C Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which... alpha-tubulin 5 56 0.0866 0
BFA1 YJR053W Component of the GTPase-activating Bfa1p-Bub2p complex involved in multiple cell...   5 49   0.0865
SEC23 YPR181C GTPase-activating protein; component of the Sec23p-Sec24p heterodimeric complex ... GTPase activating protein (GAP) 5 30   0.0001
ERJ5 YFR041C Endoplasmic reticulum protein that may function as a cochaperone, as suggested b...   4 8   0
  YBR138C     4 1   0
UFE1 YOR075W t-SNARE required for ER membrane fusion and vesicular traffic, integral membrane... t-SNARE (ER) 4 18   0.0007
NOT3 YIL038C Subunit of the CCR4-NOT complex, which is a global transcriptional regulator wit... CCR4 transcriptional complex component 4 21   0.1981
SEC31 YDL195W Essential phosphoprotein component (p150) of the COPII coat of secretory pathway... COPII coat of secretory pathway vesicles component (p150) 4 9   0
DER1 YBR201W Endoplasmic reticulum membrane protein, required for ER-associated protein degra...   4 20   0.1431
EAF3 YPR023C Esa1p-associated factor, nonessential component of the NuA4 acetyltransferase co...   4 106   0.1604
ALG12 YNR030W Alpha-1,6-mannosyltransferase localized to the ER; responsible for the addition ... mannosyltransferase 4 49   0.0199
HRD1 YOL013C Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradati...   4 61   0.0794
MKC7 YDR144C GPI-anchored aspartyl protease (yapsin) involved in protein processing; shares f... aspartyl protease|related to Yap3p|yapsin 2 4 12   0
SEC17 YBL050W Peripheral membrane protein required for vesicular transport between ER and Golg...   4 11   0
ADE3 YGR204W Cytoplasmic trifunctional enzyme C1-tetrahydrofolate synthase, involved in singl... C1-tetrahydrofolate synthase 4 10   0
CLN3 YAL040C G1 cyclin involved in cell cycle progression; activates Cdc28p kinase to promote... G1 cyclin 4 71   0.0101
HAC1 YFL031W bZIP transcription factor (ATF/CREB1 homolog) that regulates the unfolded protei... bZIP (basic-leucine zipper) protein 4 50   0.0038
ERV29 YGR284C Protein localized to COPII-coated vesicles, involved in vesicle formation and in... ER-Golgi transport vesicle protein 4 24   0.0185
HEM1 YDR232W 5-aminolevulinate synthase, catalyzes the first step in the heme biosynthetic pa... 5-aminolevulinate synthase 4 10   0
  YKL206C     4 3   0
KAR2 YJL034W ATPase involved in protein import into the ER, also acts as a chaperone to media... HSP70 family|mammalian BiP (GRP78 or HSPA5) homolog 4 20   0
COS8 YHL048W Nuclear membrane protein, member of the DUP380 subfamily of conserved, often sub...   4 4   0
ERD2 YBL040C Integral membrane protein that binds to the HDEL motif in proteins destined for ... HDEL receptor 4 8   0.0067
SEC24 YIL109C Component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat; ... vesicle coat component 4 11   0.1347
KAR9 YPL269W Karyogamy protein required for correct positioning of the mitotic spindle and fo...   4 82   0
CSM1 YCR086W Nucleolar protein that forms a complex with Lrs4p which binds Mam1p at kinetocho...   4 123   0.0001
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide ... Hsp70 family 4 80   0.0648
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes, interact... histone acetyltransferase SAGA complex member|transcription factor 4 119 -0.5513 0

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